Browsing by Author "Kutlay, Oya"

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Anti-emetic efficacy of tropisetron and metoclopramide
(Sage Publications, 1996) Yılmazlar, Aysun; Yılmazlar, Tuncay; Gürpınar, Ercan; Korun, Nusret; Kutlay, Oya; Uludağ Üniversitesi/Tıp Fakültesi/Anesteziyoloji Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Genel Cerrahi Anabilim Dalı.
Post-operative vomiting, especially in ambulatory surgical patients, remains a troublesome problem. This placebo-controlled, randomized, prospective double-blind trial was designed to evaluate the efficacy of two prophylactic antiemetic regimens on post-operative vomiting in 1-day thyroid surgery. Altogether 60 elective surgical patients were followed for 4 h post-operatively. All patients were American Society of Anesthesiologists physical status of I or II and aged between 22 and 60 years: group 1 was saline control; in groups 2 and 3, metoclopramide (0.2 mg/kg) or tropisetron (5 mg) was administered, respectively, as an intravenous single dose during induction. Patients were pre-medicated. A standardized anaesthetic technique consisting of thiopentone-succinylcholine for induction and fentanyl-nitrous oxide-halothane-pancuronium for maintenance of anaesthesia was used. A 'rescue' anti-emetic was provided in case of continued vomiting or at the patient's request. Anti-emetic inefficacy was defined as request for rescue anti-emetic and/or vomiting episode during the first 4 h post-operation. The number of patients vomiting was 12/20 (60%), 10/20 (50%) and 1/20 (5%) within the first 2 h post-operation in groups 1, 2 and 3, respectively (P > 0.05 for groups 1 and 2; P < 0.01 for groups 2 and 3; P < 0.001 for groups 1 and 3). In group 2, three patients required rescue medication during the first 2 h post-operation, but no significant difference was observed between groups 2 and 3 (P > 0.05). None of the cases in any of the groups needed any rescue medication during postoperative 2 - 4 h. It is concluded that tropisetron is a highly effective anti-emetic drug in the prophylaxis of postoperative vomiting.
Bedside percutaneous tracheostomy experience with 72 critically ill patients
(Lippincott Williams & Wilkins, 2000) Kahveci, Ferda Şöhret; Gören, Suna; Kutlay, Oya; Özcan, Berin; Korfalı, Gülsen; Uludağ Üniversitesi/Tıp Fakültesi/Anestezi ve Reanimasyon Anabilim Dalı.; 0000-0002-1190-6831; 0000-0003-4820-2288; AAI-3551-2021; AAG-9356-2021; 6602405968; 7006563257; 6602199747; 6603825848; 6701462594
Tracheostomy is necessary in intensive care unit (ICU) patients requiring prolonged mechanical ventilation. As an alternative to the standard surgical method, percutaneous techniques are available. Seventy-two patients were electively selected for percutaneous tracheostomy (PCT) in a nine-bed combined medical-surgical intensive care unit. PCT was performed at bedside with the Porter Percutaneous Tracheostomy Kit that uses the Griggs technique. The procedure time and early complications were recorded. The procedure was successful in all patients. The average duration of placement was 7.4 min. There were no tracheostomy-related deaths. Major bleeding occurred in three patients and required surgical intervention. In one patient, minor bleeding occurred at the stoma site that resolved with applied pressure. Wound infections were treated with local antiseptics in two patients. These findings suggest that PCT is a simple, quick and safe procedure.
Blood loss from diagnostic laboratory patient and anemia
(Galenos Yayincilik, 2010-12-01) Girgin, Nermin Kelebek; ÖZKAYA, GÜVEN; İŞÇİMEN, REMZİ; KELEBEK GİRGİN, NERMİN; İşçimen, Remzi; Hazıroğlu, Erkan; Hacıferat, Nedret; Özkaya, Güven; Yılmazlar, Tijen; Kutlay, Oya; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Anestezi ve Reanimasyon Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Biyoistatistik Anabilim Dalı.; 0000-0003-0297-846X; HKP-2533-2023; AAI-8104-2021; A-4421-2016; AAH-7250-2019
Objective: Anemia is very common problem in critically ill patients, and it has many deleterious effects of morbidity and mortality, decreased in oxygen carrying capacity. Phlebotomy is an important factor contributing to anemia and the need for transfusion. We aimed to evaluate the volumes of blood drawn for laboratory tests from critically ill patients, and effect on anemia and transfusion practices.Materials and Methods: The study was conducted on 60 critically ill patients. Data were recorded daily including volume of the withdrawn blood, hemoglobin (Hb), indication for transfusion, and number of units transfused. Acute Physiology and Chronic Health Evaluation (APACHE) II ve Sequential Organ Failure Assessment (SOFA) scores, the length of stay (LOS) in the intensive care unit (ICU).Results: Thirty six of the patients (60%) that transfused had significantly higher admitting APACHE II and SOFA scores (p<0.01, p<0.001). The average total volume drawn per patient was 13.05 mL for the 24-hour period except the first day in admission the ICU. The mean volume drawn the first day was detected as 27.90 mL. Total volumes drawn were significantly higher in patients that transfused at the end of second and third week (p<0.001, p < 0.001). The mean pretransfusion Hb level was 8.17 g/dL, and 44.5% of all transfusions were performed within the first week. The mean ICU LOS was longer in transfused patients (p<0.001) and mortality in the transfused patients also was significantly higher (p<0.05).Conclusion: Blood drawn and transfusion need increased with prolonged ICU stay. Additionally, patients' health condition affects the requirement of transfusion.
Comparison of different priming techniques on the onset time and intubating conditions of rocuronium
(Lippincott Williams & Wilkins, 2002-07) Yavaşçaoğlu, Belgin; Cebelli, V; Kelebek, Nermin; Uçkunkaya, Nesimi; Kutlay, Oya; Uludağ Üniversitesi/Tıp Fakültesi/Anesteziyoloji & Reanimasyon Anabilim Dalı.; AAI-7914-2021; AAG-9356-2021; 6602742300; 6507927878; 7801569062; 6701807296; 6602199747
Background and objective: The aim was to compare the effects of two different priming doses and priming intervals with the standard intubating dose of rocuronium on the onset time and intubation conditions. Methods: After induction of anaesthesia, 75 patients were randomly assigned to one of five groups. Patients in Group I received a priming dose of rocuronium 0.06 mg kg(-1) followed 2 min later by rocuronium 0.54 mg kg(-1), Group 2 received a priming dose of 0.10 mg kg(-1) followed 2 min later by a rocuronium injection of 0.50 mg kg(-1). Group 3 was given a priming dose of 0.06 mg kg(-1) followed 3 min later by administration 0.54 mg kg(-1) where Group 4 received a priming dose of 0.10 mg kg(-1) followed 3 min later by injection of 0.50 mg kg(-1). Group 5 received a placebo injection followed 3 min later by rocuronium 0.60 mg kg(-1). Results: Priming with a 3 min priming interval shortened the onset time of rocuronium irrespective of the dosage of (P < 0.001). Clinical duration of action was significantly longer after priming in Group 4 than in Group 5. Clinically acceptable intubation conditions were obtained in all patients. Conclusions: Priming with a 3 min priming interval was effective when rapid tracheal intubation with rocuronium was necessary. However, priming with rocuronium should be used carefully with special attention given to the possibility of hypoxia and aspiration of gastric contents in awake patients.
Comparison of esmolol to nitroglycerine in controlling hypotension during nasal surgery
(Aves, 2012-08-01) Güney, Ayla; Kaya, Fatma Nur; Yavaşcaoğlu, Belgin; Gurbet, Alp; Selmi, Nazan Has; Kaya, Şener; Kutlay, Oya; Güney, Ayla; KAYA, FATMA NUR; GURBET, ALP; YAVAŞCAOĞLU, BELGİN; Selmi, Nazan Has; Kaya, Şener; Kutlay, Oya; Uludağ Üniversitesi/Tıp Fakültesi/Anesteziyoloji ve Reanimasyon Anabilim Dalı.; 0000-0003-4820-2288; 0000-0002-6503-8232; EXO-4828-2022; HPG-2667-2023; AAG-9356-2021; A-7994-2018; FVA-4074-2022; CYU-8986-2022; FFP-7118-2022
Objective: The aim of this study was to compare esmolol to nitroglycerine in terms of effectiveness in controlling hypotension during nasal surgery.Materials and Methods: After approval by our institutional Ethics Committee, 40 patients were recruited and randomized into two drug groups: esmolol (Group E) and nitroglycerine (Group N). In group E, a bolus dose of 500 mu g/kg esmolol was administered over 30 sec followed by continuous administration at a dose of 25-300 mu g/kg/min to maintain systolic arterial pressure at 80 mmHg. In group N, nitroglycerine was administered at a dose of 0.5-2 mu g/kg/min.Results: During the hypotensive period, systolic arterial pressure, diastolic arterial pressure, mean arterial pressure, and heart rate were decreased 24%, 33%, 27% and 35%, respectively, in group E (p<0.001, p<0.001, p<0.001, p<0.001) and were decreased 30%, 33%, 34% and 23%, respectively, in group N (p<0.001, p<0.001, p<0.001, p<0.001). The decrease in heart rate was higher in group E during the hypotensive period (p=0.048). During the recovery period, diastolic arterial pressure and heart rate were decreased 9% and 18%, respectively, in group E (p=0.044, p<0.001). Systolic arterial pressure, diastolic arterial pressure, and mean arterial pressure were decreased 7%, 3% and 7%, respectively, in group N (p=0.049, p=0.451, p=0.045).Conclusion: Esmolol provides hemodynamic stability and good surgical field visibility and should be considered as an alternative to nitroglycerine.
Comparison of the efficacy of 2 mg versus 5 mg tropisetron in the management of post-operative nausea and vomiting
(Sage Publications, 2001) Kutlay, Özden; Yılmazlar, Aysun; Tokat, Oğuz; Kutlay, Oya; Yılmazlar, Tuncay; Türker, Gürkan; Uludağ Üniversitesi/Tıp Fakültesi/Anesteziyoloji Anabilim Dalı.; 0000-0002-3019-581X; AAG-9356-2021; AAI-6642-2021; 6701388235; 6603597913; 6602199747; 6701800362; 7003400116
A randomized, double-blind, placebo-controlled study was carried out to investigate the efficacy of 2 mg versus 5 mg tropisetron in the prevention of postoperative nausea and vomiting. Patients between 22 and 64 years old who were undergoing surgery under general anaesthesia and who had been classified according to the American Society of Anesthesiologists criteria with physical status I or II were included in this trial. Sixty female patients were recruited and divided into three groups (n = 20 in each group). Patients in group 1 received saline solution as control, whereas in groups 2 and 3, 2 mg or 5 mg tropisetron, respectively, was administered intravenously as a single dose during the induction of anaesthesia. The number of patients vomiting within the first 2 h following the operation was significantly less in groups 2 and 3 compared with that in group 1 (one of 20 for each of the groups 2 and 3 versus 12 of 20 in group 1). Three patients required rescue anti-emetic medication in each of the groups 2 and 3. In conclusion, 2 mg tropisetron appears to be equally as efficacious as 5 mg in preventing post-operative nausea and vomiting.
A comparison of the laryngeal mask airway and cuffed oropharyngeal airway during percutaneous dilatational tracheostomy
(Saudi Med Jarmed Forces Hospital, 2007-07) Girgin, Nermin Kelebek; Kahveci, Şöhret Ferda; Yavaşçaoǧlu, Belgin; Kutlay, Oya; Uludağ Üniversitesi/Tıp Fakültesi/Anesteziyoloji ve Reanimasyon Anabilim Dalı.; 0000-0003-4820-2288; AAI-7914-2021; AAH-7250-2019; AAG-9356-2021; 55663009300; 6602405968; 6602742300; 6602199747
Delayed pneumothorax and contralateral hydrothorax induced by a left subclavian central venous catheter: A case report
(Hospital Clinicas, Univ Sao Paulo, 2010-05) Girgin, Nermin Kelebek; Arıcı, Semih; Türker, Gürkan; Otlar, Banu; Hotaman, Leyla; Kutlay, Oya; Uludağ Üniversitesi/Tıp Fakültesi/Anesteziyoloji ve Reanimasyon Anabilim Dalı.; 0000-0002-3019-581X; AAH-7250-2019; AAI-6642-2021; 55663009300; 35800905700; 7003400116; 14627601000; 23481868500; 6602199747
Diallyl-Nor-Toksiferin' in anestezide kullanılışı
(Bursa Üniversitesi, 1975) Sağlam, Figen; Kutlay, Oya; Bursa Üniversitesi/Tıp Fakültesi/Anesteziyoloji ve Reanimasyon Anabilim Dalı.
Bu çalışmada yeni bir kürar, diallyl- bis- nor- toksiferin diklorid kullanılmıştır ve diğer kürarlarla kıyaslanmıştır. Ameliyat süresince rahat bir çalışma olanağı sağlaması ve ameliyat bittikten sonra yeterli solunumun sağlanabilmesi bakımından diğer kürarlardan üstün olduğu belirtilmiştir.
Diethylether ve methoxyflurane anestezisinin kan şeker düzeyine etkilerinin karşılaştırılması
(Bursa Üniversitesi, 1982) Ömür, Nedret; Kutlay, Oya; Bursa Üniversitesi/Tıp Fakültesi/Anesteziyoloji ve Reanimasyon Anabilim Dalı.
Bu çalışmada Diethylether ve Methoxyflurane’ ın kan şekeri düzeyine etkileri 20 olgu üzerinde araştırılmış ve sonuçlar karşılaştırılarak değerlendirilmiştir.
The effect of nursing-implemented sedation on the duration of mechanical ventilation in the ICU
(Ulusal Travma ve Acil Cerrahi Derneği, 2010-11-01) Yılmaz, Canan; Girgin, Nermin Kelebek; Özdemir, Nurdan; Kutlay, Oya; Uludağ Üniversitesi/Tıp Fakültesi/Anesteziyoloji ve Reanimasyon Anabilim Dalı.; 0000-0002-1510-0667; N-3608-2019; AAH-7250-2019; 56526391600; 55663009300; 57212543974; 6602199747
BACKGROUND We aimed to compare the effects of nursing-implemented sedation protocol and daily interruption of sedative infusion on the duration of mechanical ventilation. METHODS Fifty patients receiving mechanical ventilation and requiring sedation in the intensive care unit (ICU) were randomly selected to receive either daily interruption of sedative infusion (Group P, n=25) or nursing-implemented sedation protocol (Group N, n=25). In Group P, daily interruption of sedative infusions without any sedation protocol was performed by physicians. In Group N, nursing-implemented sedation protocol prepared by physicians was applied. In this group, if the ideal level of sedation was not achieved, information was given by nurses to physicians. Patients in each group were compared according to demographic variables, duration of mechanical ventilation and sedation, length of stay in the ICU, and mortality. RESULTS Demographic variables, length of stay in the ICU and mortality were similar between the two groups. In Group P, duration of sedation and mechanical ventilation were significantly shorter than in Group N. Light sedation was seen more frequently in Group P and deep sedation in Group N. CONCLUSION Daily interruption of sedative infusions provided shorter duration of sedation and mechanical ventilation than nursing-implemented sedation with protocol. Although nurse-implemented sedation protocol has been found acceptable, if the number of nurses is lacking, we believe the nurse-implemented sedation protocol should not be applied.
Efficacy of antiseptic-impregnated catheters on catheter colonization and catheter-related bloodstream infections in patients in an intensive care unit
(W. B. Saunders, 2006) Osma, Selcan; Kahveci, Ferda; Kaya, Fatma Nur; Akalın, Halis; Özakın, Cüneyt; Yılmaz, Emel; Kutlay, Oya; Uludağ Üniversitesi/Tıp Fakültesi/Mikrobiyoloji ve Enfeksiyon Hastalıkları Anabilim.; Uludağ Üniversitesi/Tıp Fakültesi/Anesteziyoloji Anabilim Dalı.; 0000-0003-4820-2288; AAI-8213-2021; AAG-9356-2021
This study was conducted to evaluate the impact of central venous catheters impregnated with chlorhexidine and silver sulphadiazine on the incidence of colonization and catheter-related bloodstream infection in critically ill patients. One hundred and thirty-three patients requiring central venous catheterization were chosen at random to receive either an antiseptic-impregnated triple-lumen catheter (N = 64) or a standard triple-lumen catheter (N = 69). The mean (SD) durations of catheterization for the antiseptic and standard catheters were 11.7 (5.8) days (median 10; range 3-29) and 8.9 (4.6) days (median 8.0; range 3-20), respectively (P = 0.006). Fourteen (21.9%) of the antiseptic catheters and 14 (20.3%) of the standard catheters had been colonized at the time of removal. (P = 0.834). Four cases (6.3%) of catheter-related bloodstream infection were associated with antiseptic catheters and one case (1.4%) was associated with a standard catheter (P = 0.195). The catheter colonization rates were 18.7/1000 catheter-days for the antiseptic catheter group and 22.6/1000 catheter-days for the standard catheter group (P = 0.640). The catheter-related bloodstream infection rates were 5.3/1000 catheter-days for the antiseptic catheter group and 1.6/1000 catheter-days for the standard catheter group (P = 0.452). In conclusion, our results indicate that the use of antiseptic-impregnated central venous catheters has no effect on the incidence of either catheter colonization or catheter-related bloodstream infection in critically ill patients.
Eklamsi tedavisinde diazepam'ın yeri
(Bursa Üniversitesi, 1979) Kutlay, Oya; Akgün, Tahsın; Özcan, Berrin; Bursa Üniversitesi/Tıp Fakültesi.
Eklamsi vakalarında sedasyonun çok etkili bir yeri olduğu bilinmektedir ve bu amaçla eşitli droglar kullanılmaktadır. Son yıllarda bazı çalışmacılar Diazepam 'ın bu konuda iyi sonuçlar verdiğini belirtmektedirler. Bu yazıda bir eklamsi vakasında kaynak önerileri dikkate alınarak Diazepam kullanılmış ve sonuç tartışılmıştır.
Endoscopic diagnosis of laryngeal injury following endotracheal intubation
(Taylor & Francis, 1999) Kahveci, Şöhret Ferda; Erişen, Levent; Özcan, Berin; Kutlay, Oya; Tezel, İlker; Uludağ Üniversitesi/Tıp Fakültesi/Anesteziyoloji ve Yoğun Bakım Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Kulak Burun Boğaz Anabilim Dalı.; 0000-0003-4820-2288; AAG-9356-2021; C-3960-2015; 6602405968; 6602590279; 6603825848; 6602199747; 7801465342
Laryngeal injury following endotracheal intubation occurs in many patients and intensive care physicians may remain unaware of the incidence of complications. This study evaluated the incidence of laryngeal injury in a group of patients who had intubation for > 4 days in an intensive care unit. In 14 patients, laryngeal injuries were evaluated by flexible and/or rigid endoscopes as soon as the patients were extubated or decannulated. In 64% of the patients, pathological signs, including ulceration, oedema, granulation and fibrosis, were determined by endoscopic examination. Postintubation injuries were very common. Endoscopic examination may be one of the best ways to diagnose these lesions because it allows early diagnosis and can be performed at the patients' bedside.
Evde mekanik ventilasyon uygulaması
(Uludağ Üniversitesi, 2005-05-25) Kaya, Fatma Nur; Kahveci, Ferda; Kutlay, Oya; Uludağ Üniversitesi/Tıp Fakültesi/Anesteziyoloji ve Reanimasyon Anabilim Dalı.
Evde mekanik ventilasyon uygulaması, tam veya kısmi ventilasyon desteği gereken, kliniği stabil, kronik solunum yetmezliği olan olguların tedavisinde kullanılmaktadır. Evde uzun süreli mekanik ventilasyon uygulanan olguyu sunduk. 86 yaşında erkek olgu, TUR-P operasyonunun ikinci gününde klinikte ani kardiyak arrest gelişmesi üzerine, kardiyopulmoner resüsitasyonu takiben yoğun bakım ünitesine (YBÜ) alındı (APACHE II Skoru:30, GKS:3). Olgu konjestif kalp yetmezliği ve kronik obstrüktif akciğer hastalığı hikayesine sahipti. Ventilatör desteğinden tamamen ayrılamadı. Ventilatöre bağımlı olgu için YBÜ’de sekizinci ayından sonra evde mekanik ventilasyon programı planlandı. Olgu eve gönderilmeden önce, tedavisinde gerekli spesifik ihtiyaçları ve olgunun bakımından sorumlu kişinin eğitimi sağlandı. Kronik obstrüktif akciğer hastalığı akut atağının tedavisi ve fizik muayene için YBÜ uzmanı tarafından düzenli ziyaretleri yapıldı. Olgu yirmi iki ay sonra öldü. Bu dönemde iki kez YBÜ desteği gerekli oldu.
Genel anestezi sırasında orta kulak basıncındaki değişiklik
(Bursa Üniversitesi, 1981) Kutlay, Oya; Tezel, İlker; Şahin, Şükran; Bursa Üniversitesi/Tıp Fakültesi/Anesteziyoloji ve Reanimasyon Anabilim Dalı.; Bursa Üniversitesi/Tıp Fakültesi/Kulak Burun Boğaz Anabilim Dalı.
Genel anestezi sırasında verilen N2 O'in vücudun içerisinde hava bulunan boşluklarında hızla gelişen belirgin bir genişlemeye neden olduğu bilinmektedir. Bu yazıda farklı yoğunluklarda verilen N2 O'in orta kulak basıncına etkisi araştırılmış ve tartışılmıştır.
Guillain-barre syndrome and human immunodeficiency virus
(Aves, 2014-04-01) Girgin, Nermin Kelebek; İsçimen, Remzi; Yılmaz, Emel; Kahveci, S. Ferda; Kutlay, Oya; KELEBEK GİRGİN, NERMİN; İŞÇİMEN, REMZİ; YILMAZ, EMEL; KAHVECİ, FERDA ŞÖHRET; Uludağ Üniversitesi/Tıp Fakültesi/Anesteziyoloji ve Reanimasyon Anabilim Dalı/Yoğun Bakım Ünitesi.; Uludağ Üniversitesi/Tıp Fakültesi/Enfeksiyon Hastalıkları ve Mikrobiyoloji Anabilim Dalı.; 0000-0003-4820-2288; AAG-9356-2021; AAH-7250-2019; HKP-2533-2023; AAI-8104-2021
Guillain-Barre syndrome (GBS) is an acute disease characterised by symmetrical muscle weakness, loss of sensation and reflex. There is usually a viral infection at the beginning of the disease. Here, we report a GBS case which did not respond to any treatment strategy at first and was diagnosed as Human Immunodeficiency Virus positive (HIV+) during the search for the aetiology. A 32-year-old male patient who presented to a medical centre with symptoms of gait disturbance and arm and leg numbness was found to have albuminocytologic dissociation upon cerebrospinal fluid examination. After the diagnosis of GBS, immunoglobulin G (IVIG) therapy (400 mg kg(-1) day-1 5 days) was started as a standard therapy. This therapy was repeated due to a lack of improvement of symptoms. During this therapy, the patient was sent to our clinic with symptoms of respiratory failure and tetraplegia. He was conscious, cooperative, haemodynamically stable and his arterial blood gas analyses were: pH: 7.28, PaO2 : 74.4 mmHg, PCO2 : 63.8 mmHg. He was intubated, mechanically ventilated and underwent plasmapheresis. After the investigation of aetiology, HIV(+), CD4/ CD8: 0.17, absolute CD4: 71 cells mL(-1) were detected and antiretroviral therapy was started. The patient died from multiple organ failure due to sepsis on day 35. In conclusion, HIV infection should be kept in mind in GBS patients, especially those not responding to routine treatment. As a result, not only could the patient receive early and adequate treatment, but also HIV infection transmission would be avoided.
Halotan ve ısofluran'ın kan glukoz düzeyine etkilerinin karşılaştırılması
(Uludağ Üniversitesi, 1993-07-22) Uçkunkaya, Nesimi; Kutlay, Oya; Uludağ Üniversitesi/Tıp Fakültesi/Anesteziyoloji ve Reanimasyon Anabilim Dalı.
Halolan ve Isofluran'm kan glukoz düzeyine etkilerini karşılaştırmak amacıyla, diyabet ile ilgili patolojisi olmayan ASA I grubunda 30 olgu 15'er kişilik iki gruba ayrılarak I. Gruba Halotan, II. Gruba Isofluran anestezisi verildi. İndiksiyondan önce, entübasyondan sonra, indüksiyon dan önce 30. ve 60. dakikalarda ve ayılma odasını terk etmeden önce kan örnekleri alınarak kan glukoz düzeyleri incelendi. Sonuçlarımıza göre, her iki grupta elde edilen kan şekeri ortalamaları kontrol değerlerine göre anlamlı derecede yüksek bulmuştur. Gruplararası karşılaşılaştırmada Isofluran grubunda bu değerlerin Halolan grubuna göre anlamlı derecede yüksek olduğu saptanmıştır (p < 0.05, p < 0.05, p < 0.001). Bu nedenle, diyabetik olgularda Halolan’ın Isofluran 'a göre daha uygun olduğu sonucuna varıldı.
Halothane ve ethrane anestezisinin kan şekeri düzeyine etkilerinin karşılaştırılması
(Bursa Üniversitesi, 1982) Ömür, Nedret; Kutlay, Oya; Bursa Üniversitesi/Tıp Fakültesi/Anesteziyoloji ve Reanimasyon Anabilim Dalı.
Bu çalışmada Halothane ve Ethrane'ın kan şekeri düzeyine etkileri 20 olgu üzerinde araştırılmış ve sonuçlar karşılaştırılarak değerlendirilmiştir.
Influences of alternate therapy protocol and continuous infectious disease consultation on antibiotic susceptibility in ICU
(Springer, 1999) Akalın, Halis; Kahveci, Ferda Şöhret; Özakın, Cüneyt; Helvacı, Safiye; Gedikoğlu, Suna; Kutlay, Oya; Töre, Okan; Uludağ Üniversitesi/Tıp Fakültesi/Mikrobiyoloji ve Enfeksiyon Hastalıkları Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Anesteziyoloji ve Reanimasyon Anabilim Dalı.; 0000-0003-4820-2288; 57207553671; 6602405968; 57200678942; 6602103491; 6603407548; 6602199747; 6505909596
In this study, the effects of alternate use of imipenem and cef-operazone/sulbactam(CFP/Sul) on antibiotic resistance in the intensive care unit (ICU) were investigated, Between 1 April 1993 and 1 April 1994, the infectious diseases consultant saw patients when required and there was no alternative therapy for antibiotics. For the following 2 years, the same consultant followed up each patient from admission to discharge by daily visits to the ICU and an alternative therapy protocol was initiated, The most common microorganisms were found to be Acinetobacter baumannii and Staphylococcus aureus, followed by Pseudomonas aeruginosa and Klebsiella pneumoniae, respectively, in the two periods. This study demonstrated that sensitivity rates of imipenem, ciprofloxacin and aminoglycosides were improved as a result of this protocol.