Browsing by Author "Uluduz, Derya"

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    Cerebral venous sinus thrombosis as a rare complication of systemic lupus erythematosus: Subgroup analysis of the venost study
    (Elsevier, 2019-12-01) Duman, Taşkın; Demirci, Seden; Uluduz, Derya; Kozak, Hasan Hüseyin; Demir, Serkan; Mısılı, Cemile Handan; Küçükoğlu, Hayriye; Çınar, Nilgün; Domaç, Fusun Mayda; Öztürk, Şerefnur; Sungur, Mehmet Ali; Yayla, Vildan; Karahan, Ali Yavuz; Afşar, Nazire; Göksu, Eylem Özaydın; Aytaç, Emrah; Yeşilot, Nilufer; İnce, Birsen; Yalın, Osman ÖzgÜr; Oruç, Serdar; Şenol, Mehmet Güney; Yılmaz, Arda; Gökçe, Mustafa; Kuosbeci, Özge Yılmaz; Uzuner, Gülnür; Çaglayan, Hale Zeynep Batur; Açıkgöz, Mustafa; Kurucu, Hatice; Özdağ, Fatih; Ekmekçi, Hakan; Cabalar, Murat; Yürekli, Vedat Ali; Güneş, Taşkın; Genç, Hamit; Utku, Uygar; Şahin, Sevki; Tokuc, Firdevs Ezgi Ucan; Uzuner, Nevzat; BektaŞ, Hesna; Kablan, Yüksel; Göksel, Başak Karakurum; Milanlioğlu, Aysel; Örken, Dilek Necioğlu; Aluclu, Ufuk; Midi, İpek; Çolakoğlu, Sena; Tüfekçi, Ahmet; Bakar, Mustafa; Nazliel, Bijen; Taşçılar, Nida; Goksan, Baki; VENOST Study Grp; Tüfekçi, Ahmet; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Nöroloji Anabilim Dalı; JHK-8029-2023
    Aim: Systemic lupus erythematosus (SLE) is an unusual risk factor for cerebral venous sinus thrombosis (CVST). As few CVST patients with SLE have been reported, little is known regarding its frequency as an underlying etiology, clinical characteristics, or long-term outcome. We evaluated a large cohort of CVST patients with SLE in a multicenter study of cerebral venous thrombosis, the VENOST study, and their clinical characteristics. Material and Method: Among the 1144 CVST patients in the VENOST cohort, patients diagnosed with SLE were studied. Their demographic and clinical characteristics, etiological risk factors, venous involvement status, and outcomes were recorded. Results: In total, 15 (1.31%) of 1144 CVST patients had SLE. The mean age of these patients was 39.9 +/- 12.1 years and 13 (86.7%) were female. Presenting symptoms included headache (73.3%), visual field defects (40.0%), and altered consciousness (26.7%). The main sinuses involved were the transverse (60.0%), sagittal (40.0%), and sigmoid (20.0%) sinuses. Parenchymal involvement was not seen in 73.3% of the patients. On the modified Rankin scale, 92.9% of the patients scored 0-1 at the 1-month follow-up and 90.9% scored 0-1 at the 1-year follow-up. Conclusions: SLE was found in 1.31% of the CVST patients, most frequently in young women. Headache was the most common symptom and the CVST onset was chronic in the majority of cases. The patient outcomes were favorable. CVST should be suspected in SLE patients, even in those with isolated chronic headache symptoms with or without other neurological findings.
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    Gender differences in older adults with chronic migraine in Turkey
    (Wiley, 2015-05) Özge, Aynur; Uluduz, Derya; Selekler, Macit; Öztürk, Musa; Baykan, Betül; Çınar, Nilgün; Domaç, Füsun M.; İnan, Levent E.; Akyol, Ali; Bolay, Hayrunnisa; Uzuner, Gülnur T.; Erdemoğlu, Ali K.; Öksüz, Nevra; Temel, Gülhan O.; Zarifoğlu, Mehmet; Uludağ Üniversitesi/Tıp Fakültesi/Nöroloji Anabilim Dalı.; EHN-5825-2022; 6603411305
    Aim: Chronic migraine is a growing and disabling subtype of migraine with different risk factors and clinical features, even in older adults. We sought to define and differentiate clinical features of chronic migraine in older adults. We also aimed to compare major clinical features of chronic migraine in older adults with those in younger people of both sexes. Methods: We used electronic dataset (Turkish Headache Database) from 13 tertiary headache centers in Turkey. Electronic dataset included detailed headache-defining features according to ICHD-II criteria based on face-to-face interviews and examination by a headache specialist. Using statistical methods, clinical variables of chronic migraine in older adults were compared with those of younger adults. We included 915 patients with chronic migraine (mean age 43.80 +/- 13.95 years); 83.3% were females. In total, 301 patients (32.9%) with chronic migraine aged >50 years were compared with 614 patients aged <50 years. Results: There was no significant change in men with increasing age. However, duration of headache history, severity of attacks, previous histories of motion sickness and positive family history of headaches were significantly different in women with increasing age. Further sex-related differences have been shown in parameters such as attack duration, quality and associated nausea. Conclusion: Chronic migraine is an infrequent type of migraine and shows age-related changes in some phenotypic characteristics, such as severity of attacks, especially in women aged older than 50 years. Furthermore, positive family history of headaches and history of motion sickness increase the likelihood of developing chronic migraine in older women, indicating involvement of some gender-related, but as-yet unknown, genetic factors.