Browsing by Author "Ural, Zeynep"

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    Characteristics and survival results of peritoneal dialysis patients suffering from COVID-19 in Turkey: A multicenter national study
    (Karger, 2022-09-13) Gürsu, Meltem; Öztürk, Savaş; Arıcı, Mustafa; Şahin, İdris; Gökçay Bek, Sibel; Yılmaz, Mürvet; Koyuncu, Sümeyra; Karahisar Sıralı, Semahat; Ural, Zeynep; Dursun, Belda; Yüksel, Enver; Uzun, Sami; Sipahi, Savaş; Ahbap, Elbis; Artan, Ayşe Serra; Altunören, Orçun; Tunca, Onur; Ayar, Yavuz; Gök-Oğuz, Ebru; Yılmaz, Zülfükar; Kahvecioğlu, Serdar; Aşıcıoğlu, Ebru; Oruç, Ayşegül; Altıparmak, Mehmet Rıza; Aydın, Zeki; Huddam, Bülent; Dolarslan, Mürşide Esra; Azak, Alper; Bakirdoğen, Serkan; Yalçın, Ahmet Uğur; Karadağ, Serhat; Ulu, Memnune Sena; Güngör, Özkan; Arı Bakir, Elif; Odabas, Ali Riza; Seyahi, Nurhan; Yıldız, Alaattin; Ateş, Kenan; ORUÇ, AYŞEGÜL; Bursa Uludağ Üniversitesi/Tıp Fakültesi/İç Hastalıkları Anabilim Dalı/Nefroloji Anabilim Dalı.; 0000-0002-0342-9692 ; AAH-4002-2021
    Background: We aimed to study the characteristics of peritoneal dialysis (PD) patients with Coronavirus disease-19 (COVID-19), determine the short-term mortality and other medical complications, and delineate the factors associated with COVID-19 outcome.Methods: In this multicenter national study, we included PD patients with confirmed COVID-19 from 27 centers. The baseline demographic, clinical, laboratory, and radiological data and outcomes at the end of the first month were recorded.Results: We enrolled 142 COVID-19 patients (median age:52 years). 58.2% of patients had mild disease at diagnosis. Lung involvement was detected in 60.8% of patients. 83 (58.4%) patients were hospitalized, 31 (21.8%) patients were admitted to intensive care unit and 24 needed mechanical ventilation. 15 (10.5%) patients were switched to hemodialysis and hemodiafiltration was performed for four (2.8%) patients. Persisting pulmonary symptoms (n=27), lower respiratory system infection (n=12), rehospitalization for any reason (n=24), malnutrition (n=6), hypervolemia (n=13), peritonitis (n=7), ultrafiltration failure (n=7) and in PD modality change (n=8) were reported in survivors. 26 patients (18.31%) died in the first month of diagnosis. The non-survivor group was older, comorbidities were more prevalent. Fever, dyspnea, cough, serious-vital disease at presentation, bilateral pulmonary involvement, and pleural effusion were more frequent among non-survivors. Age (OR:1.102; 95%CI: 1.032-1.117; p: 0.004), moderate-severe clinical disease at presentation (OR:26.825; 95%CI: 4.578-157.172; p<0.001) and baseline CRP (OR:1.008; 95%CI; 1.000-1.016; p:0.040) were associated with first-month mortality in multivariate analysis.Conclusions: Early mortality rate and medical complications are quite high in PD patients with COVID-19. Age, clinical severity of COVID-19, and baseline CRP level are the independent parameters associated with mortality.
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    The longitudinal evolution of post-COVID-19 outcomes among hemodialysis patients in Turkey
    (Elsevier Science Inc, 2022-06-03) Ozturk, Savas; Turgutalp, Kenan; Arici, Mustafa; Gorgulu, Numan; Tonbul, Halil Zeki; Eren, Necmi; Gencer, Vedat; Ayli, Mehmet Deniz; Pembegul, Irem; Dolarslan, Murside Esra; Ural, Zeynep; Colak, Hulya; Ozler, Tuba Elif; Can, Ozgur; Demir, Mehmet Emin; Altunoren, Orcun; Huddam, Bulent; Onec, Kursad; Demirelli, Bulent; Aydin, Zeki; Altun, Eda; Alagoz, Selma; Ayar, Yavuz; Eser, Zeynep Ebru; Berktas, Bayram; Yilmaz, Zulfukar; Ates, Eser Uslu; Yuksel, Enver; Sahin, Gizem Kumru; Aktar, Merve; Cebeci, Egemen; Dursun, Belda; Kocak, Sibel Yucel; Yıldız, Abdülmecit; Kazan, Sinan; Gok, Mahmut; Sengul, Erkan; Tugcu, Murat; Ozturk, Ramazan; Kahvecioglu, Serdar; Kara, Ekrem; Kaya, Bulent; Sahin, Garip; Sakaci, Tamer; Sipahi, Savas; Kurultak, Ilhan; Durak, Beyza Algul; Altiparmak, Mehmet Riza; Ecder, Sabahat Alisir; Karadag, Serhat; Dincer, Mevlut Tamer; Ozer, Hakan; Bek, Sibel Gokcay; Ulu, Memnune Sena; Gungor, Ozkan; Bakir, Elif Ari; Odabas, Ali Riza; Seyahi, Nurhan; Yildiz, Alaattin; Ates, Kenan; YILDIZ, ABDULMECİT; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Nefroloji Anabilim Dalı.; HIG-9032-2022
    Introduction: Hemodialysis (HD) patients have increased risk for short-term adverse outcomes of COVID-19. However, complications and survival at the post-COVID-19 period have not been published extensively.Methods: We conducted a national, multicenter observational study that included adult maintenance HD patients recovered from confirmed COVID-19. A control HD group without COVID-19 was selected from patients in the same center. We investigated the characteristics and outcomes in the follow-up of HD patients and compare them with the non-COVID-19 group.Results: A total of 1223 patients (635 patients in COVID-19 group, 588 patients in non-COVID-19 group) from 47 centers were included in the study. The patients' baseline and HD characteristics were almost similar. The 28th-day mortality and mortality between 28th day and 90th day were higher in the COVID-19 group than non-COVID-19 group (19 [3.0%] patients vs. none [0%]; 15 [2.4%] patients vs. 4 [0.7%] patients, respectively). The presence of respiratory symptoms, rehospitalization, need for home oxygen therapy, lower respiratory tract infection, and arteriovenous (AV) fistula thrombosis was significantly higher in the COVID-19 group in both the first 28 days and between 28 and 90 days. In the multivariable analysis, age (odds ratio [OR] [95% CI]: 1.029 [1.004-1.056]), group (COVID-19 group vs. non-COVID-19 group) (OR [95% CI]: 7.258 [2.538-20.751]), and vascular access type (tunneled catheter/AV fistula) (OR [95% CI]: 2.512 [1.249-5.051]) were found as independent parameters related to 90-day mortality.Conclusion: In the post-COVID-19 period, maintenance HD patients who have had COVID-19 have increased rehospitalization, respiratory problems, vascular access problems, and high mortality compared with the non-COVID-19 HD patients.