2005 Cilt 24 Sayı 1-2-3-4

Permanent URI for this collectionhttps://hdl.handle.net/11452/13143

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    Alterations in some blood parameters after high level ethanol ıntake
    (Uludağ Üniversitesi, 2005-06-07) Yağcı, Artay; Yalçın, Murat; Uludağ Üniversitesi/Veteriner Fakültesi.
    The effects of high level ethanol intake on some blood parameters over a 50 days period were examined in 36 Sprague Dawley rats divided into 3 treatment groups: Ad libitum fed control group (n=12), sucrose group (n=12) fed with solution of sucrose so calorie intake equated with the ethanol group, and ethanol group (n=12) added ethanol (15 % v/v) in drinking water. Significant decreases (p<0.05) were noted in ethanol group’s white- and red-blood cell counts, haemoglobin concentration, erythrocyte diameter, erythrocyte sodium and potassium levels, while significant (p<0.05) increases were observed in their mean corpuscular volume and mean corpuscular haemoglobin levels. No changes were observed in hematocrit level. Results of this study suggest that high level ethanol intake in rats causes alterations in blood cells count and in erythrocyte diameter and in erythrocyte element composition and this negative effect of ethanol on blood parameters did not stem from the energy of ethanol.