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Item Body fat distribution has no effect on serum visfatin levels in healthy female subjects(Academic Press - Elsevier Science, 2010-03) Ersoy, Canan; Sadıkoğlu, Ganime; Orhan, Hasan; Güçlü, Metin; Sarandöl, Emre; Akgün, Meral Demirci; Özçakır, Alis; İmamoğlu, Şazi; Uludağ Üniversitesi/Tıp Fakültesi/İç Hastalıkları Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Aile Hekimliği Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Tıbbi Biyokimya Anabilim Dalı.; 0000-0002-2593-7196; 0000-0001-5588-2037; ABI-4847-2020; ABE-1716-2020; AAG-8209-2021; AAH-8861-2021; 6701485882; 22956348700; 36126806400; 15073842600; 55943324800; 36125941900; 9733230000; 6602297533Obesity is the presence of either abnormal absolute amount or relative proportion of body fat. Contrary to gluteal obesity, visceral obesity is associated with different metabolic alterations including insulin resistance (IR). A relatively new adipocytokine visfatin is shown to be expressed predominantly in visceral fat and exhibit insulin-mimicking effects in rodents. It is still unclear whether serum visfatin levels are associated with increased total or visceral fat mass in humans. The aim of our study was to investigate the relation between visfatin and obesity parameters namely body mass index (BMI) and waist circumference (WaC) and IR in healthy female subjects. Eighty one female subjects >= 20 years of age, having no diagnosis of glucose intolerance or diabetes, hypertension and dyslipidemia were chosen. The patients were divided into four groups according to their BMI and WaC values. Serum visfatin and HOMA-IR levels did not differ among groups. No correlation was detected between serum visfatin levels and obesity and metabolic parameters. In conclusion, we demonstrated that body fat distribution did not affect serum visfatin levels in healthy female subjects. Further studies are needed to clarify the exact factors influencing and determining serum visfatin levels and its clinical reflections.Item Mammography utilization among Turkish women(Asian Pacific Organization Cancer Prevention, 2010) Sadıkoğlu, Ganime; Özçakır, Alis; Doğan, Fatma Oflu; Gökgöz, Şehsuvar; Bilgel, Nazan Gönül; Uludağ Üniversitesi/Tıp Fakültesi/Aile Hekimliği Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Genel Cerrahi Anabilim Dalı.; 0000-0001-5588-2037; 0000-0002-4539-5849; AAG-8209-2021; 9733230000; 37080414800; 6603238737; 7801564702; 22956348700In Turkey, breast cancer is the leading type of cancer and cause of cancer-related deaths among women, but information is limited on mammography practices. The objectives of the present study were to identify associations between attitudes and knowledge about mammography and socio-demographic indicators and having a mammogram. The participants of this cross-sectional and descriptive study were 1,208 women who attended the primary health care unit serving as a training unit of the medical faculty or the outpatient clinic for breast diseases of the same medical faculty's hospital between October and December 2007. A printed questionnaire covering socio-demographic variables, family history of breast cancer, mammography practices, and attitudes and knowledge of mammography was filled out in face-to-face interviews with the authors. Women with previously diagnosed breast cancer were excluded from the study. We performed chi square and logistic regression analyses. We found that 12.7% of the women had no knowledge of mammography, and 57.3 % had never had a mammogram. Fifty point six percent of our study group reported that they had had a clinical breast examination at least once, and 51.1% were aware of breast self examination (BSE). Need factors such as age and health-system-related factors such as awareness of BSE and having CBE were found to be more important than the socio-economic factors in mammography use. Mammography was accepted by 92.3% as a useful screening method for early detection of breast cancer and as a necessity for women of 50 years and over by the 90.6% of the study group. We found a positive attitude towards mammography and its importance but limited usage.Publication To evaluate the differences of risk factors in patients with lower extremity venous disease(Saudi Medical Journal, 2007-08) Sadıkoğlu, Ganime; Özçakır, Aliş; Ercan, İlker; Özkaya, Güven; Sadıkoğlu, Yurtkuran M.; Uludağ Üniversitesi/Tıp Fakültesi/Aile Hekimliği Anabilim Dalı; Uludağ Üniversitesi/Tıp Fakültesi/Biyoistatistik Anabilim Dalı; Uludağ Üniversitesi/Tıp Fakültesi/Girişimsel Radyoloji Anabilim Dalı; 0000-0001-5588-2037; 0000-0002-2382-290X; 0000-0003-0297-846X; FTO-3267-2022; AAG-8209-2021; ABF-2367-2020; A-4421-2016; INO-2041-2023; 22956348700; 9733230000; 6603789069; 16316866500; 6602402845Objective: To determine whether there is a difference between risk factors in patients diagnosed to have clinically documented lower extremity venous disease after confirming the diagnosis radiologically by ultrasonographic and venographic evaluation. Methods: This study was performed from January 2002 to January 2005 in Bursa, the fourth biggest city of Turkey, situated in the west of the country in the Marmara Region. The study center is a private imaging center working in conjunction with the Department of Health, which performs diagnostic, and therapeutic vascular protocols in the region. Five hundred and fifty-three cases with clinically and radiologically documented diagnoses were evaluated with Multi-Variate Statistical Package 3.13 for the presence of pre-defined clusters of 14 different variables. Other statistical analyses were performed by the Statistical Package for Social Sciences, version 13.0. Results: Three different clusters were defined. The variables used to define the clusters were: age, gender, educational level, presence of smoking, amount of smoking (pack/per year), disease symptoms, presence of heart disease, and radiologically documented diagnosis. Conclusions: Chronic venous insufficiency and varicose veins are venous system diseases that are most commonly present in association with more than one concomitant risk factor.Item Turkish general practitioners and complementary/alternative medicine(Mary Ann Liebert, 2007-11) Mazıcıoğlu, M. Mümtaz; Özçakır, Aliş; Sadıkoğlu, Ganime; Bayram, Nuran; Bilgel, Nazan; Beyhan, Işık; Uludağ Üniversitesi/İktisadi ve İdari Bilimler Fakültesi/Ekonometri Bölümü.; Uludağ Üniversitesi/Tıp Fakültesi/Aile Hekimliği Anabilim Dalı.; 0000-0001-5492-184X; 0000-0001-5588-2037; 0000-0002-4539-5849; AAG-9068-2021; AAG-8209-2021; 9733230000; 22956348700; 13609585600; 7801564702; 23027059100Background: Complementary and alternative medicine (CAM) is in the spotlight of society. However, what is the position of physicians at this point? Objectives: To determine general practitioners' (GP) knowledge, attitudes, and approaches to CAM. Methods: All GPs (n = 521) practicing in Bursa Province, Turkey were surveyed by a questionnaire. Results: Responses from 49% of GPs were analyzed. Alltogether, most of our physicians (96.5%) had not received any education about CAM, wanted to learn more (74.4%), and their knowledge levels were low (60.8%). About half of them (51%) believed in the efficiency of CAM, whereas 38.0% did not. GPs desire more information about herbal medicine and acupuncture. Only 29% of GPs were using some type of CAM for themselves. Conclusions: GPs are aware of the subject's importance and want to learn more about CAM and improve their knowledge. It would be reasonable to provide training possibilities for GPs, primarily for the CAM types highly used by the population and most requested by the physicians.