Browsing by Author "Öztürk, Savaş"

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Characteristics and survival data of patients with primary focal segmental segmental glomerulosclerosis: Tsn-goldmulti-center study
(Oxford Univ Press, 2023-06-01) Dheir, Hamad; Cebeci, Egemen; Karadağ, Serhat; Yıldız, Abdulmecit; Güller, Nurana; Altiparmak, Mehmet Riza; Eren, Necmi; Yilmaz, Zulfikar; Basturk, Taner; Sipahi, Savas; Sahin, Gulizar; Bakar, Betul; Okyay, Gulay Ulusal; Suleyman, Gultekin; Piskinpasa, Serhan Vahit; Dursun, Belda; Balal, Mustafa; Turgutalp, Kenan; Guzel, Fatma Betul; Kutlay, Sim; Tatar, Erhan; Elcioglu, Omer Celal; Karakan, Sebnem; Kayalar, Arzu Ozdemir; FarukAkcay, Omer; Yildirim, Tolga; Sahin, Idris; Sahin, Garip; Ogutmen, Melike Betul; Tokgoz, Bulent; Tunca, Onur; Gul, Cuma Bulent; Kurultak, Ilhan; Torun, Dilek; Ayar, Yavuz; Uzun, Sami; Yavuz, Mahmut; Oto, Ozgür Akın; Dinçer, Mevlüt Tamer; Ergül, Metin; Öztürk, Savaş; Türkmen, Aydın; YILDIZ, ABDULMECİT; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Nefroloji Anabilin Dalı.; HIG-9032-2022
Characteristics and survival results of peritoneal dialysis patients suffering from COVID-19 in Turkey: A multicenter national study
(Karger, 2022-09-13) Gürsu, Meltem; Öztürk, Savaş; Arıcı, Mustafa; Şahin, İdris; Gökçay Bek, Sibel; Yılmaz, Mürvet; Koyuncu, Sümeyra; Karahisar Sıralı, Semahat; Ural, Zeynep; Dursun, Belda; Yüksel, Enver; Uzun, Sami; Sipahi, Savaş; Ahbap, Elbis; Artan, Ayşe Serra; Altunören, Orçun; Tunca, Onur; Ayar, Yavuz; Gök-Oğuz, Ebru; Yılmaz, Zülfükar; Kahvecioğlu, Serdar; Aşıcıoğlu, Ebru; Oruç, Ayşegül; Altıparmak, Mehmet Rıza; Aydın, Zeki; Huddam, Bülent; Dolarslan, Mürşide Esra; Azak, Alper; Bakirdoğen, Serkan; Yalçın, Ahmet Uğur; Karadağ, Serhat; Ulu, Memnune Sena; Güngör, Özkan; Arı Bakir, Elif; Odabas, Ali Riza; Seyahi, Nurhan; Yıldız, Alaattin; Ateş, Kenan; ORUÇ, AYŞEGÜL; Bursa Uludağ Üniversitesi/Tıp Fakültesi/İç Hastalıkları Anabilim Dalı/Nefroloji Anabilim Dalı.; 0000-0002-0342-9692 ; AAH-4002-2021
Background: We aimed to study the characteristics of peritoneal dialysis (PD) patients with Coronavirus disease-19 (COVID-19), determine the short-term mortality and other medical complications, and delineate the factors associated with COVID-19 outcome.Methods: In this multicenter national study, we included PD patients with confirmed COVID-19 from 27 centers. The baseline demographic, clinical, laboratory, and radiological data and outcomes at the end of the first month were recorded.Results: We enrolled 142 COVID-19 patients (median age:52 years). 58.2% of patients had mild disease at diagnosis. Lung involvement was detected in 60.8% of patients. 83 (58.4%) patients were hospitalized, 31 (21.8%) patients were admitted to intensive care unit and 24 needed mechanical ventilation. 15 (10.5%) patients were switched to hemodialysis and hemodiafiltration was performed for four (2.8%) patients. Persisting pulmonary symptoms (n=27), lower respiratory system infection (n=12), rehospitalization for any reason (n=24), malnutrition (n=6), hypervolemia (n=13), peritonitis (n=7), ultrafiltration failure (n=7) and in PD modality change (n=8) were reported in survivors. 26 patients (18.31%) died in the first month of diagnosis. The non-survivor group was older, comorbidities were more prevalent. Fever, dyspnea, cough, serious-vital disease at presentation, bilateral pulmonary involvement, and pleural effusion were more frequent among non-survivors. Age (OR:1.102; 95%CI: 1.032-1.117; p: 0.004), moderate-severe clinical disease at presentation (OR:26.825; 95%CI: 4.578-157.172; p<0.001) and baseline CRP (OR:1.008; 95%CI; 1.000-1.016; p:0.040) were associated with first-month mortality in multivariate analysis.Conclusions: Early mortality rate and medical complications are quite high in PD patients with COVID-19. Age, clinical severity of COVID-19, and baseline CRP level are the independent parameters associated with mortality.
Characteristics of primary glomerular diseases patients with hematuria in Turkey: the data from TSN-GOLD Working Group
(Springer, 2020-10-27) Şumnu, Abdullah; Türkmen, Kültigin; Cebeci, Egemen; Türkmen, Aydın; Eren, Necmi; Seyahi, Nurhan; Oruç, Ayşegül; Dede, Fatih; Derici, Ülver; Baştürk, Taner; Şahin, Garip; Sipahioğlu, Murat; Şahin, Gülizar Manga; Tatar, Erhan; Dursun, Belda; Sipahi, Savaş; Yılmaz, Mürvet; Süleymanlar, Gültekin; Ulu, Sena; Güngör, Özkan; Kutlay, Sim; Bahçebaşı, Zerrin Bicik; Şahin, İdris; Kurultak, İlhan; Sevinç, Can; Yılmaz, Zülfikar; Kazancıoğlu, Rümeyza Turan; Çavdar, Caner; Candan, Ferhan; Aydın, Zeki; Oygar, Deren; Gül, Bülent; Altun, Bülent; Paydaş, Saime; Uzun, Sami; İstemihan, Zülal; Ergül, Metin; Dinçer, Mevlüt Tamer; Güllulü, Mustafa; Pişkinpaşa, Serhan; Akçay, Ömer Faruk; Ünsal, Abdulkadir; Koyuncu, Sümeyra; Gök, Mahmut; Öztürk, Savaş; ORUÇ, AYŞEGÜL; GÜLLÜLÜ, MUSTAFA; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Nefroloji Anabilim Dalı.; 0000-0002-0342-9692; AAH-4002-2021; CTG-8811-2022
Purpose Hematuria is one of the most common laboratory findings in nephrology practice. To date, there is no enough data regarding the clinical and histopathologic characteristics of primary glomerular disease (PGD) patients with hematuria in our country. Methods Data were obtained from national multicenter (47 centers) data entered into the Turkish Society of Nephrology Glomerular Diseases (TSN-GOLD) database between May 2009 and June 2019. The data of all PGD patients over the age of 16 years who were diagnosed with renal biopsy and had hematuria data were included in the study. Demographic characteristics, laboratory and biopsy findings were also recorded. Results Data of 3394 PGD patients were included in the study. While 1699 (50.1%) patients had hematuria, 1695 (49.9%) patients did not have hematuria. Patients with hematuria had statistically higher systolic blood pressure, serum blood urea nitrogen, creatinine, albumin, levels and urine pyuria. However, these patients had statistically lower age, body mass index, presence of hypertension and diabetes, eGFR, 24-h proteinuria, serum total, HDL and LDL cholesterol, and C3 levels when compared with patients without hematuria. Hematuria was present 609 of 1733 patients (35.8%) among the patients presenting with nephrotic syndrome, while it was presented in 1090 of 1661 (64.2%) patients in non-nephrotics (p < 0.001). Conclusion This is the first multicenter national report regarding the demographic and histopathologic data of PGD patients with or without hematuria. Hematuria, a feature of nephritic syndrome, was found at a higher than expected in the PGDs presenting with nephrotic syndrome in our national database.
Demographic and clinical characteristics of primary glomerular diseases in Turkey
(Springer, 2014-12-01) Öztürk, Savaş; Sumnu, Abdullah; Seyahi, Nurhan; Sipahioglu, Murat; Artan, Serra; Bicik, Zerrin; Kutlay, Sim; Keles, Mustafa; Oygar, Deren; Odabas, Ali Riza; Kayatas, Mansur; Dursun, Belda; Sayarlioglu, Hayriye; Trablus, Sinan; Taymez, Dilek Guven; Özdemir, Ali Abbas; Sahin, Gulizar Manga; Altun, Bulent; Azak, Alper; Altıntepe, Lutfullah; Suleymanlar, Gultekin; Koc, Mehmet; Selcuk, Yilmaz; Kazancıoğlu, Rumeyza; Erkoç, Reha; Gursu, Meltem; Küçük, Mehmet; Akçaoglu, Selma Alagöz; Yıldız, Abdulmecid; Ünal, Aydın; Akarsu, Özger; Ates, Kenan; Cankaya, Erdem; Türkmen, Aydın; Güllülü, Mustafa; GÜLLÜLÜ, MUSTAFA; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Nefroloji Anabilim Dalı.
The aim of our study was to delineate the demographic and clinical properties of primary glomerular diseases of adult population in our country in the light of global knowledge.All over the country, a total of 25 centers entered data between May 2009 and July 2012 to the database created by 'Glomerulonephritis Study Group' of Turkish Society of Nephrology. Demographic and clinical characteristics, specific diagnoses of glomerular diseases and biopsy findings recorded to the database were analyzed.Among the 1,274 patients, who had renal biopsy within the defined time period, 55 % were male and 45 % were female. The mean age was 40.8 +/- A 14.6 years. The most frequent indication for biopsy was nephrotic syndrome (57.8 %), followed by nephritic syndrome including rapidly progressive glomerulonephritis (16.6 %) and asymptomatic urinary abnormalities (10.8 %). The most frequent primary glomerular disease was membranous nephropathy (28.8 %), followed by focal segmental glomerulosclerosis (19.3 %) and IgA nephropathy (17.2 %).The presented study displayed important data about the epidemiology of primary glomerular diseases among adults in our country. The predominance of membranous nephropathy in contrast to other countries, in which the most frequent etiology is IgA nephropathy, seems to be due to differences in the indications for renal biopsy.
Demographic and clinical characteristics of rapidly progressive glomerulonephritis in Turkey
(Oxford Univ Press, 2020-06-01) Aydın, Zeki; Türkmen, Kultiğin; Dede, Fatih; Yaşar, Emre; Öztürk, Savaş; Tatar, Erhan; Şahin, Garip; Şahin, Gülizar Manga; Oto, Özgür Akın; Sumnu, Abdullah; Eroğlu, Eray; Dinçer, Mevlüt Tamer; Dursun, Belda; Eren, Necmi; Sevinç, Mustafa; Güzel, Fatma Betül; Yalın, Serkan Feyyaz; Kutlay, Sim; Apaydın, Süheyla; Berktaş, Hacı Bayram; Kazan, Sinan; Dheir, Hamad; Bora, Feyza; Baştürk, Taner; Şahin, İdris; Aydin, Mehmet; AYDIN, MEHMET AKİF; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Nefroloji Anabilim Dalı.; 0000-0002-5665-7402; AAJ-8220-2020
Demographic, clinical and laboratory characteristics of rapidly progressive glomerulonephritis in Turkey: Turkish Society of Nephrology-Glomerular Diseases (TSN-GOLD) Working Group
(Springer, 2020-09-29) Aydın, Zeki; Türkmen, Kültigin; Dede, Fatih; Yaşar, Emre; Öztürk, Savaş; Aydın, Mehmet; Tatar, Erhan; Şahin, Garip; Manga, Gülizar; Oto, Özgür; Şumnu, Abdullah; Eroğlu, Eray; Dinçer, Tamer; Dursun, Belda; Eren, Necmi; Sevinç, Mustafa; Güzel, Fatma Betül; Yalın, Serkan; Kutlay, Sim; Apaydın, Süheyla; Berktaş, Hacı Bayram; Kazan, Sinan; Dheir, Hamad; Bora, Feyza; Baştürk, Taner; Sahin, Idris; AYDIN, MEHMET AKİF; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Dahiliye Anabilim Dalı/Nefroloji Bilim Dalı.; 0000-0002-5665-7402; AAJ-8220-2020
Background In our study, diagnostic and demographic characteristics of patients diagnosed with RPGN by biopsy, clinical and laboratory findings in our country were investigated. Methods Data were obtained from the Turkish Society of Nephrology Glomerular Diseases (TSN-GOLD) Working Group database. Demographic characteristics, indications for biopsy, diagnosis of the glomerular diseases, comorbidities, laboratory and biopsy findings of all patients were recorded. According to their types, RPGN patients were classified as type 1 (anti-GBM related), type 2 (immuncomplex related) and type 3 (pauci-immune). Results Of 3875 patients, 200 patients with RPGN (mean age 47.9 +/- 16.7 years) were included in the study which constitutes 5.2% of the total glomerulonephritis database. Renal biopsy was performed in 147 (73.5%) patients due to nephritic syndrome. ANCA positivity was found in 121 (60.5%) patients. Type 1 RPGN was detected in 11 (5.5%), type 2 RPGN in 42 (21%) and type 3 RPGN in 147 (73.5%) patients. Median serum creatinine was 3.4 (1.9-5.7) mg/dl, glomerular filtration rate was 18 (10-37) ml/min/1.73m(2)and proteinuria 2100 (1229-3526) mg/day. The number of crescentic glomeruli ratio was ratio 52.7%. It was observed that urea and creatinine increased and calcium and hemoglobin decreased with increasing crescentic glomerular ratio. Conclusions Our data are generally compatible with the literature. Advanced chronic histopathological findings were prominent in the biopsy of 21 patients. Early biopsy should be performed to confirm the diagnosis of RPGN and to avoid unnecessary intensive immunosuppressive therapy. In addition to the treatments applied, detailed data, including patient and renal survival, are needed.
Is the severity of glomerular igg staining in patient with iga nephropathy useful for predicting poor renal prognosis? The data from Tsn-gold working group
(Oxford University Press, 2020-06-01) Turgutalp, Kenan; Cebeci, Egemen; Türkmen, Aydin; Derici, Ülver; Seyahi, Nurhan; Eren, Necmi; Dede, Fatih; Güllülü, Mustafa; Baştürk, Taner; Şahin, Gülizar Manga; Yılmaz, Mürvet; Sipahi, Savaş; Şahin, Garip; Ulu, Memnune Sena; Tatar, Erhan; Gündoğdu, Ali; Kazancıoğlu, Rümeyza Turan; Sevinç, Can; Güngör, Özkan; Şahin, İdris; Kutlay, Sim; Kurultak, İlhan; Aydın, Zeki; Altun, Bülent; Dursun, Belda; Yılmaz, Zülfikar; Uzun, Özcan; Süleymanlar, Gültekin; Candan, Ferhan; Sezer, Siren; Tanburoğlu, Derya Başak; Bahçebaşı, Zerrin Bicik; Taymez, Dilek Güven; Oygar, Deren; Akçalı, Esra; İstemihan, Zulal; Akçay, Ömer Faruk; Dinçer, Mevlüt Tamer; Ergül, Metin; Yenigün, Ezgi; Türkmen, Kültigin; Öztürk, Savaş; GÜLLÜLÜ, MUSTAFA; Bursa Uludağ Üniversitesi/Tıp Fakültesi.; CTG-8811-2022
Membranous nephropathy in Turkey: Turkish society of nephrology glomeruler diseases (tsn-gold) database results
(Oxford University Press, 2020-06-01) Yıldız, Abdülmecit; Ulu, Memnune Sena; Oruç, Ayşegül; Uçar, Ali Rıza; Öztürk, Savaş; Alagöz, Selma; Eren, Necmi; Koçyiğit, İsmail; Cevher, Simal Köksal; Haraş, Ali Burak; Sumnu, Abdullah; Arınsoy, Turgay; Şahin, Garip; Süleymanlar, Gültekin; Çavdar, Caner; Gahin, Gizem Kumru; Kurultak, İlhan; Ünsal, Abdülkadir; Şahin, Gülizar Manga; Kazan, Sinan; Vatansever, Bülent; Dikeç, Mehmet; Dursun, Belda; Sayarlıoğlu, Hayriye; Türkmen, Kultiin; Artan, Ayşe Serra; Aktaş, Nimet; Yılmaz, Zülfikar; Behlül, Ahmet; Dheir, Hamad; Kutlay, Sim; Seyahi, Nurhan; YILDIZ, ABDULMECİT; ORUÇ, AYŞEGÜL; Bursa Uludağ Üniversitesi/Tıp Fakültesi.; 0000-0002-0342-9692; AAH-4002-2021; HIG-9032-2022
Predictors of renal survival in patients with idiopathic membranous nephropathy
(Oxford University, 2017-05) Uçar, Ali; Çalışkan, Yaşar; Yeğit, Osman; Türkmen, Aydın; Cebeci, Egemen; Öztürk, Savaş; Mirioğlu, Şafak; Demir, Erol; Yıldız, Abdulmecit; Uludağ Üniversitesi/Tıp Fakültesi/Sağlık Uygulama ve Araştırma Merkezi/Organ Nakli Merkezi.
The prevalence, clinical and pathological characteristics of primary focal segmental glomerulosclerosis in Turkish adults: The data from tsn-gold (Turkish society of nephrology glomerular diseases) working group
(Oxford Univ Press, 2020-06-01) Kurultak, İlhan; Güngör, Özkan; Öztürk, Savaş; Dirim, Ahmet Burak; Eren, Necmi; Yenigün, Ezgi; Dal, Elbis Ahbap; Dinçer, Mevlüt Tamer; Bora, Feyza; Akgür, Suat; Sumnu, Abdullah; Dursun, Belda; Sipahi, Savaş; Getinkaya, Hakkı; Sahin, Idris; Şahin, Garip; Yılmaz, Mürvet; Vatansever, Bülent; Aydın, Emre; Ulu, Memnune Sena; Gündoğan, Ali; ÜstOndağ, Sedat; Sayarlıoğlu, Hayriye; Şahin, Gizem Kumru; Elcioğlu, Ömer Celal; Aydın, Zeki; Selcuk, Nedim Yılmaz; Önal, Ceren; Oruç, Meriç; Küçük, Mehmet; Aktaş, Nimet; Derici, Ulver; Süleymanlar, Gültekin; AKGÜR, SUAT; Bursa Uludağ Üniversitesi/Tıp Fakültesi; JIX-1144-2023
The relationship between severity of interstitial fibrosis and anemia in patient with primary glomerulonephritis: The data from TSN-gold working group
(Oxford Univ Press, 2020-06-01) Cebeci, Egemen; Turgutalp, Kenan; Öztürk, Savaş; Özlük, Yasemin; Bek, Sibel Gökçay; Şumnu, Abdullah; Seyahi, Nurhan; Yavuz, Mahmut; Pişkinpaşa, Serhan Vahit; Akçay, Ömer Faruk; Sakaci, Tamer; Şahin, Garip; Tokgöz, Bülent; Şahin, Gülizar Manga; Bozacı, Ilter; Dursun, Belda; Sipahi, Savaş; Kayalar, Arzu Özdemir; Süleymanlar, Gültekin; Ulu, Memnune Sena; Güzel, Fatma Betül; Kutlay, Sim; Parmaksız, Ergün; Koz, Süleyman; Kurultak, İlhan; Selçuk, Nedim Yılmaz; Yildırım, Yaşar; Gürsu, Meltem; Çavdar, Caner; Timuçin, Meryem; Aydın, Zeki; Oygar, Deren; Kahvecioğlu, Serdar; Kibar, Müge Uzerk; Torun, Dilek; Taymez, Dilek Güven; Küçük, Mehmet; Demir, Serap; Koç, Leyla; Sezer, Siren; Duranay, Murat; Bardak, Simge; Altintepe, Lüftullah; Koç, Mehmet; Azak, Alper; Odabaş, Ali Rıza; Yılmaz, Zülfikar; Paydaş, Saime; YAVUZ, MAHMUT; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Nefroloji Anabilim Dalı.; EHM-7377-2022
Trends of primary glomerular disease in Turkey from 2009 to 2017: A regional registry report from tsn-gold working group
(Oxford Univ, 2020-06-01) Gül, Cuma Bülent; Küçük, Mehmet; Öztürk, Savaş; Demir, Erol; Eren, Necmi; Süönü, Abdullah; Seyahi, Nurhan; Dede, Fatih; Derici, Ülver; Koç, Yener; Şahin, Garip; Oymak, Oktay; Şahin, Gulizar Manga; Tatar, Erhan; Dursun, Belda; Dheir, Hamad; Apaydın, Suheyla; Süleymanlar, Gültekin; Ulu, Memnune Sena; Altunören, Orçun; Kutlay, Sim; Meşe, Meral; Şahin, İdris; Üstündağ, Sedat; Türkmen, Kultiğin; Yılmaz, Mehmet Emin; Kazancıoğlu, Rümeyza Turan; Uzun, Özcan; Candan, Ferhan; Aydın, Zeki; Oygar, Deren; Aktaş, Nimet; Erdem, Yunus; Paydaş, Saime; Taymez, Dilek Güven; Can, Başak; Kiykim, Ahmet; Koç, Leyla; Sezer, Siren; Duranay, Murat; Bardak, Simge; Altıntepe, Lüftullah; Kaya, Burcu; Azak, Alper; Ecder, Sabahat Alışır; Cavdar, Caner; Selçuk, Nedim Yılmaz; Güllülü, Mustafa; GÜLLÜLÜ, MUSTAFA; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Nefroloji Anabilim Dalı.; CTG-8811-2022