Browsing by Author "Baruchel, Andre"
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Item Generic formulations of imatinib for treatment of Philadelphia chromosome-positive leukemia in pediatric patients(Wiley, 2018-12) Suttorp, Meinolf; Metzler, Markus; Millot, Frederic; Shimada, Hiroyuki; Bansal, Deepak; Kalwak, Krzysztof; Sedlacek, Petr; Baruchel, Andre; Biondi, Andrea; Hijiya, Nobuko; Schultz, Kirk R.; Schrappe, Martin; Güneş, Adalet Meral; Uludağ Üniversitesi/Tıp Fakültesi/Çocuk Hematoloji Kliniği.; EXD-8400-2022; 24072843300Since the patent for imatinib has expired, the role of generic imatinib (GI) in the management of Philadelphia chromosome-positive (Ph+) leukemia in pediatric patients has had ongoing discussion. Some studies in adults demonstrated that equivalent doses of GI and branded imatinib (BI) result in comparable plasma concentrations and clinical efficacy. However, other studies found that GI users are more likely to stop imatinib, with intolerance and decreased persistence as the main causes. Economic factors also heavily influence GI selection. This article aims to review the present knowledge to support further discussion on the role of GI in the management of pediatric Ph+ leukemia.Item Prognostic discrimination of children and adolescents with chronic myeloid leukemia based on the EUTOS long term survival (ELTS) score(Amer Soc Hematology, 2016-12-02) Millot, Frederic; Guilhot, Joelle; Suttorp, Meinolf; Sedlacek, Petr; De Bont, Evelina S.; Li, Chi Kong; Kalwak, Krzysztof; Lausen, Birgitte; Culic, Srdjana; De Moerloose, Barbara; Biondi, Andrea; Baruchel, Andre; Güneş, Adalet Meral; Uludağ Üniversitesi/Tıp Fakültesi/Çocuk Hematoloji Anabilim Dalı.; EXD-8400-2022Publication Switch to subsequent line of treatment in children and adolescents with chronic myeloid leukemia (CML) treated with imatinib: Experience of the international registry for chronic myeloid leukemia in children and adolescents (I-CML-Ped Study)(Amer Soc Hematology, 2015-12-03) Millot, Frederic; Guilhot, Joelle; Suttorp, Meinolf; Meunier, Anne Sophie; Meral, Güneş Adalet; Sedlacek, Petr; de Bont, Eveline; Li, Chi Kong; Kalwak, Krzysztof; Lausen, Birgitte; Culic, Srdjana; De Moerloose, Barbara; Biondi, Andrea; Baruchel, Andre; MERAL GÜNEŞ, ADALET; Uludağ Üniversitesi/Tıp Fakültesi/Çocuk Hematoloji Anabilim Dalı.; IMO-4290-2023