Browsing by Author "Dilek, Saffet"

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    Comparison of tumor markers and clinicopathological features in serous and mucinous borderline ovarian tumors
    (Imr Press, 2012) Alanbay, İbrahim; Aktürk, Erhan; Çoksüer, Hakan; Ercan, Cihangir Mutlu; Karaşahin, Kazım Emre; Dede, Murat; Yenen, Müfit Cemal; Dilek, Saffet; Ozan, Hakan; Uludağ Üniversitesi/Tıp Fakültesi/Kadın Hastalıkları ve Doğum Anabilim Dalı.; 7003908072
    Objective: The aim of this study was to assess tumor markers and clinicopathological findings of patients with serous and mucinous borderline ovarian tumor (BOT) features. Methods: The study consisted of 50 patients that were diagnosed with and treated for BOT between 2005- 2010 in three centers. CA125, CA19-9, and CA125+CA19-9 levels and clinicopathological features were compared in serous and mucinous histotypes. In serous and mucinous BOTs, correlations between tumor markers and demographics such as age, menopausal status, parity, clinical findings (stage, relapse, adjuvant chemotherapy, cytology, lymph node involvement and tumoral morphology (cystic-solid content, papilla, septation) were evaluated. Results: There were no significant differences between serous and mucinous tumors in the clinicopathological features such as stage, tumor markers, age, menopausal status, or cytology. In serous BOTs we found a significant relation between elevated CA 125+ CA 19-9, CA 19-9 and recurrence (p<0.05). Also there was a significant relation between elevated CA 125+ CA 19-9, CA 19-9 and cytology positivity (p<0.05). We found a significant relation in serous BOTs between elevated CA125+CA19-9, adjuvant chemotherapy and lymph node metastases (p<0.05). Also In mucinous BOTs with papilla formation we found a significant relation between elevated CA125 and CA 125+ CA19-9 (p<0.05). There was significant relation between cytology positivity and elevated CA 19-9 in mucinous BOTs (p<0.05). Conclusion: Serum tumor markers of serous and mucinous BOTs were different in relation to their clinicopathological features. This may reflect differences of serous and mucinous BOTs.
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    Prevalence of cervical cytological abnormalities in Turkey
    (Wiley, 2009-09) Ayhan, Ali; Dursun, Polat; Kuşçu, Esra; Mülayim, Barış; Haberal, Nihan; Özen, Özlem; Köse, M. Faruk; Turan, A. Taner; Özgül, Nejat; Demir, Ö. Faruk; Çavuşoğlu, H. Deniz; Yüce, Kunter; Kuzey, Gamze Mocan; Salman, M. Coşkun; Velipaşaoğlu, Melih; Yenen, Müfit C.; Dede, Murat; Onan, M. Anıl; Güner, Haldun; Taşkıran, Cağatay; Erdem, Özlem; Saraçoglu, Ferit; Serin, Serdar; Özçelik, Bülent; Soyer, Işın; Güzin, Kadir; Doğanyılmaz, Soner; Kara, Fadil; Kıran, Gürkan; Metindir, Jale; Özalp, Sinan; Vardar, M. Ali; Zeren, Handan; Dilek, Saffet; Bozkaya, Hasan; Güven, Süleyman; Ersöz, Şafak; Açıkalın, Arbil; Meydanlı, Mutlu; Çetinarslan, İlknur; Gökaslan, Hüsnü; Eren, Funda; Çelik, Çetin; Yılmaz, Osman; Çelik, Hüsnü; Aksaz, Zeliha; Koçak, Cengiz; Bağcı, Hafize; Davutoğlu, Bilge Sel; Hakverdi, Ali Ulvi; Soysal, Mehmet Emin; Kaya, Gülcan; Yanık, Ali; Arıcı, Sema; Çetin, Halit; Mutlu, Ahmet Emin; Kolusari, Ali; Kösem, Mustafa; Şahin, Güler; Demirtürk, Fazlı; Gültekin, Murat; Karaca, Mehmet; Harma, Mehmet; Harma, Müge; Batur, Şebnem; Demirbağ, Nilgün; Baykal, Cem; Doğan, Işın; Şam, Aslı Demir; Ozan, Hakan; Uludağ Üniversitesi/Tıp Fakültesi/Kadın Hastalıkları ve Doğum Anabilim Dalı.; 7003908072
    Objective: To evaluate retrospectively the prevalence of cervical cytological abnormalities in patient records obtained from healthcare centers in Turkey. Method: Demographic characteristics and data on cervical cytological abnormalities were evaluated from patients who underwent flap tests in healthcare centers in 2007. Results: Data were collected from 33 healthcare centers totaling 140 334 patients. Overall, the prevalence of cervical cytological abnormalities was 1.8%; the prevalence of ASCUS, ASC-H, LSIL, HSIL, and AGC was 1.07%, 0.07%, 0.3%, 0.17%, and 0.08%, respectively. The prevalence of preinvasive cervical neoplasia was 1.7% and the prevalence of cytologically diagnosed invasive neoplasia was 0.06%. Conclusion: The abnormal cervical cytological prevalence rate in Turkey is lower than in Europe and North America. This might be due to sociocultural differences, lack of population-based screening programs, or a lower HPV prevalence rate in Turkey.