Browsing by Author "Duru, Serap"

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    Immunization status in chronic obstructive pulmonary disease: A multicenter study from Turkey
    (Wolters Kluwer Medknow Publications, 2019-01-01) Özlü, Tevfik; Bülbül, Yılmaz; Aydın, Derya; Tatar, Dursun; Kuyucu, Tülin; Erboy, Fatma; Köseoğlu, Handan İnönü; Anar, Ceyda; Sunnetçioğlu, Aysel; Gülhan, Pınar Yıldız; Şahin, Ünal; Ekici, Aydanur; Duru, Serap; Ulaşlı, Sevinç Sarınç; Kurtipek, Ercan; Günay, Sibel; Okutan, O.; Yıldız, B. P.; Çetinkaya, P. D.; Arslan, S.; Çakmak, G.; Çırak, A. K.; Sarıoğlu, N.; Koçak, N. D.; Aktürk, U. A.; Demir, M.; Kılıç, T.; Dalli, A.; Hezer, H.; Altıntaş, N.; Acat, M.; Dağlı, C. E.; Kargı, A.; Yakar, F.; Kırkıl, G.; Baccıoğlu, A.; Gedik, C.; İntepe, Y. S.; Karadeniz, G.; Onyılmaz, T.; Saylan, B.; Baslilar, S.; Sarıman, N.; Özkurt, S.; Arınç, S.; Kanbay, A.; Yazar, E. E.; Yıldırım, Z.; Kadıoğlu, E. E.; Gül, S.; Sengül, A.; Berk, S.; Dikiş, O. S.; Kurt, O. K.; Arslan, Y.; Erol, S.; Korkmaz, C.; Balaban, A.; Erbay, Toru U.; Soğukpınar, O.; Uzaslan, E. K.; Babaoğlu, E.; Bahadir, A.; Barış, S. A.; Uğurlu, A. O.; Ilgazlı, A. H.; Fidan, F.; Kararmaz, E.; Güzel, A.; Alzafer, S.; Cortük, M.; Hocanlı, I; Ortaköylü, M. G.; Erginel, M. S.; Yaman, N.; Erbaycu, A. E.; Demir, A.; Duman, D.; Tanrıverdi, H.; Yavuz, M. Y.; Sertoğullarından, B.; Özyurt, S.; Bulcun, E.; Yüce, G. D.; Sariaydin, M.; Ayten, O.; Bayraktaroğlu, M.; Tekgül, S.; Erel, F.; Şenyiğit, A.; Kaya, S. B.; Ayık, S.; Yazıcı, O.; Akgedik, A.; Yaşar, Z. A.; Hayat, E.; Kalpaklıoğlu, F.; Sever, F.; Saraç, P.; Uğurlu, E.; Kasapoğlu, U. S.; Günlüoğlu, G.; Demirci, N. Y.; Bora, M.; Talay, F.; Özkara, B.; Yılmaz, M. U.; Yavsan, D. M.; Cetinoglu, E. D.; Balcan, M. B.; Çiftçi, T.; Havan, A.; Gök, A.; Nizam, M.; RIMPACT Study Investigators; Çetinoğlu, E. D.; Bursa Uludağ Üniversitesi; 0000-0002-7400-9089; AAH-9812-2021
    OBJECTIVE: The purpose of this study is to detect the prevalence and the factors associated with influenza and pneumococcal vaccination and outcomes of vaccination during 2013-2014 season in patients with chronic obstructive pulmonary disease (COPD) in Turkey.METHODS: This was a multicenter retrospective cohort study performed in 53 different centers in Turkey.RESULTS: During the study period, 4968 patients were included. COPD was staged as GOLD 1-2-3-4 in 9.0%, 42.8%, 35.0%, and 13.2% of the patients, respectively. Influenza vaccination rate in the previous year was 37.9%; and pneumococcus vaccination rate, at least once during in a life time, was 13.3%. Patients with older age, higher level of education, more severe COPD, and comorbidities, ex-smokers, and patients residing in urban areas had higher rates of influenza vaccination. Multivariate logistic regression analysis showed that advanced age, higher education levels, presence of comorbidities, higher COPD stages, and exacerbation rates were associated with both influenza and pneumococcal vaccination. The number of annual physician/outpatient visits and hospitalizations due to COPD exacerbation was 2.73 +/- 2.85 and 0.92 +/- 1.58 per year, respectively. Patients with older age, lower education levels, more severe COPD, comorbid diseases, and lower body mass index and patients who are male and are residing in rural areas and vaccinated for influenza had significantly higher rates of COPD exacerbation.CONCLUSIONS: The rates of influenza and pneumococcal vaccination in COPD patients were quite low, and the number of annual physician/outpatient visits and hospitalizations due to COPD exacerbation was high in Turkey. Advanced age, higher education levels, comorbidities, and higher COPD stages were associated with both influenza and pneumococcal vaccination.
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    Prognostic importance of central thrombus in hemodynamically stable patients with pulmonary embolism
    (Via Medica, 2017) Şentürk, Ayşegül; Özsu, Savaş Sedat; Duru, Serap; Çakır, Ebru; Ulaşlı, Sevinç Sarınç; Kayhan, Servet; Güzel, Aygül; Yakar, Fatih; Berk, Serdar; Demirdöǧen, Ezgi; Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Hastalıkları Anabilim Dalı.; 0000-0002-7400-9089; AAH-9812-2021; 14062849300
    Uludağ University, School of Medicine, Department of Pulmonary Medicine, Bursa, TurkeyBackground: The association between mortality and localization of central thrombus in hemodynamically stable patients with pulmonary embolism (PE) is unclear. Sufficient data are not available to help clinicians to select between low molecular weight heparin (LMWH), unfractionated heparin (UFH) and thrombolytics for the management of central thrombus. The present study aims to investigate whether central thrombus in the pulmonary artery affects 30-day mortality rate, and to compare the outcomes of different treatment approaches in patients with central thrombus. Methods: This multi-central, prospective, observational study included 874 hemodynamically stable patients with PE confirmed by multidetector computed tomography scan. The localization of the emboli was evaluated and categorized as central (saddle or at least one main pulmonary artery), lobar or distal. The primary study outcome was 30-day all-cause mortality. Results: Localization of the emboli was central in 319 (36.5%) patients, lobar in 264 (30.2%) and distal in 291 (33.2%) patients. Seventy-four (8.5%) patients died during the 30-day follow-up period. All-cause mortality rate was 11.9%, 6.8% and 6.2% in patients with central, lobar, and distal emboli, respectively (p < 0.001). Multivariate analysis did not show that hemodynamically stable central thrombus was an independent predictor of mortality. Additionally, mortality rate was not significantly different between UFH, LMWH and thrombolytic therapy groups. Conclusions: The present study showed that central thrombus was not an independent predictor of mortality in hemodynamically stable PE patients. LMWH and UFH were similarly effective in the treatment of this patient group.