Browsing by Author "Kaya, Mete"

Now showing 1 - 4 of 4

Çocuklarda akut karına yaklaşım
(Uludağ Üniversitesi, 2012-06-23) Kaya, Mete
Çocuklarda akut karın, halen tanıda ikilem yaşanan ve çocuk acillere başvurularda en sık rastlanan klinik bir durumdur. Akut karın ağrısı, hayatı tehdit eden durumdan cerrahi gerektirmeyen durumlara kadar farklı nedenlere bağlı olabilir. Her ne kadar laboratuvar ve görüntüleme yöntemleri tanıya yardımcı olsa da, hikaye ve fizik muayene daha önemlidir. Bu yazıda akut karın tanısı konulmasına yardımcı olan çalışmalar ve bu hastalara güncel yaklaşım gözden geçirilmiştir.
Cross-sectional imaging and laparoscopic findings of diaphragmatic mesothelial cysts
(W.B. Saunders, 2019-10-30) Sansar, Serpil; Özçakır, Esra; Kaya, Mete; Kandemirli, Sedat Giray; Parlak, Ayşe; Bilgin, Cem; Gürpınar, Arif Nuri; Yazıcı, Zeynep; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Çocuk Cerrahisi Anabilim Dalı.; 0000-0001-7686-2561; AAH-6766-2021; HHS-7433-2022; AAI-2303-2021; A-1409-2017; ITP-4695-2023; 22834938400; 57202853581; 57200617643; 7004350616; 6701668723
AIM: To present cross-sectional imaging, surgical findings, and follow-up results of diaphragmatic mesothelial cysts. MATERIALS AND METHODS: Radiological findings for location, size, shape, and internal structure of cysts were reviewed retrospectively. For patients that underwent surgery, surgical reports and laparoscopy images were reviewed. In conservatively managed patients, changes in size and imaging findings of the cyst were assessed during follow-up visits. RESULTS: A total of 13 paediatric cases with an imaging and/or pathological diagnosis of diaphragmatic mesothelial cyst were identified. In all cases, the cystic lesions were located between the diaphragm and the posterolateral aspect of the right lobe of the liver. Eleven lesions (84.6%) had a bi-lobulate shape. Eight of these cases underwent laparoscopic cyst aspiration/unroofing. The postoperative course was uneventful and there were no cases of recurrence. The remaining five cases were managed conservatively with follow-up available in four cases. In three cases (75%), there was reduction in the size of the cysts with a mean volume reduction of 55%. CONCLUSION: Diaphragmatic mesothelial cysts are congenital cystic lesions that are usually detected incidentally. A common pitfall is incorrect interpretation of the lesion as a hepatic cyst. Conservative management with imaging follow-up can be adopted in asymptomatic cases with typical imaging findings.
Diagnostic discordance-based inferences regarding imaging modalities in children with a preliminary diagnosis of choledochal cyst: Clinical experience and review of literature
(Galenos Yayıncılık, 2021-04-25) Özçakır, Esra; Kaya, Mete; Uludağ Üniversitesi/Tıp Fakültesi/Çocuk Cerrahisi Anabilim Dalı.; 0000-0002-0773-7430; 0000-0002-8877-5737
Introduction: Definitive diagnosis is essential for the medical and surgical management of pediatric patients with a preliminary diagnosis of a choledochal cyst. Our study aimed to investigate the roles of Magnetic Resonance Cholangiopancreatography (MRCP), Intraoperative Cholangiography (IOC) in differential and definitive diagnosis of choledochal cyst by comparing their results with the intraoperative gross pathological appearance. Materials and Methods: The medical records of seven pediatric patients preliminary diagnosed with choledochal cyst between May 2014 and January 2021 in our clinic, were retrospectively reviewed. We investigated the clinical characteristics, the MRCP and IOC results, and compared their results with the intraoperative gross pathological findings of patients with preliminarily diagnosed choledochal cyst. We evaluated the outcomes involving the preliminary diagnosis and subtype of choledochal cyst with MRCP preoperatively and with IOC and gross pathological findings intraoperatively. Results: Six patients had undergone a laparotomy and IOC procedure, and their results were: in three, the MRCP and IOC results were consistent, both revealing a Type-I choledochal cyst; in another patient, MRCP revealed a Type IV choledochal cyst, whereas IOC showed a Type-I choledochal cyst; one patient reported having a Type-II choledochal cyst in MRCP turned out to have a duodenal duplication cyst intraoperatively; the sixth operated patient had an MRCP result of Type-I choledochal cyst, but the IOC was consistent with biliary atresia and severe hydropic bile stasis. The last child was a non-operated patient whose MRCP revealed a Type-I choledochal cyst whereas contrast-enhanced liver magnetic resonance showed a simple liver cyst. Conclusions: Even though MRCP is valuable regarding choledochal cyst’s differential diagnosis, we should confirm its diagnosis by IOC and intraoperative gross pathological view because other pathologies might appear similar to choledochal cyst in MRCP.
The use of acellular matrices obtained by the esophagus, intestine, and trachea for esophageal wall repair: An experimental study on a rat model
(Springer India, 2022-08-11) GÜLER, SABİRE; Özcakır, Esra; Çelik, Fatih; Güler, Sabire; Kaya, Mete; Avcı, Zehra; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Çocuk Cerrahisi Anabilim Dalı.; Bursa Uludağ Üniversitesi/Veteriner Fakültesi/Patoloji Anabilim Dalı.; 0000-0003-2728-9521; 0000-0002-7367-6859; 0000-0002-8877-5737; W-2482-2017; AFW-3677-2022
This study aimed to evaluate the procurement, efficacy, and applications of different acellular matrices (AMs) on rat esophagi. Sixteen rats were used. Following tissue harvesting from donor rats, AMs were obtained by detergent-enzymatic treatment (DET) from the esophagus, jejunum, and trachea. Fifteen rats were allocated into groups defined by implemented AM types: esophageal (EAM), intestinal (IAM), and tracheal (TAM). According to groups, 5 x 5 mm esophageal wall defect repair was performed with AMs. Samples were examined for hyperemia, edema, inflammatory cells, and neovascularization by scoring. The existence of muscle cells was investigated with immunohistochemical assessment. The procurement of AM in vitro and its implementation on the damaged esophageal wall was achieved successfully. There was a significant difference between groups regarding hyperemia, inflammatory cells, and neovascularization (p < 0.05). Hyperemia and cell infiltration were higher, and neovascularization was poorer in TAM than in others (p < 0.05). The neovascularization was significantly higher in the EAM group (p < 0.05). Increased edema was detected in the IAM group than others, albeit with no significant difference. Staining with Masson's trichrome and desmin antibodies, showing increased inflammatory response on the matrix site, was not detected to regenerate muscle cells. Our DET approaches provided that AMs with potential for regeneration have been obtained from different tissues. Grafting by TAM caused higher grades of inflammation with poor angiogenesis and existing chondrocytes. Decreased inflammatory response of EAM was thought to be due to the native tissue-derived matrix. These results suggest that promoting self-regeneration with native tissue-derived AM can be improved and more convenient in damaged tissue repair.