Browsing by Author "Kordan, Yakup"
Now showing 1 - 20 of 52
- Results Per Page
- Sort Options
Item Association of urokinase gene 3 '-UTR T/C polymorphism with calcium oxalate urolithiasis in children(Springer, 2008-12) Öztürk, Murat; Kordan, Yakup; Cangül, Hakan; Doğan, Hasan Serkan; Kılıçarslan, Hakan; Vuruşkan, Hakan; Oktay, Bülent; Uludağ Üniversitesi/Tıp Fakültesi/Üroloji Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Tıbbi Genetik Anabilim Dalı.; ABH-5513-2020; 56781010900; 9633365800; 8911611600; 7005856022; 56007473800; 6507328150; 6602172127Introduction and objectives: Urokinase is synthesized by various cells such as kidney, pneumocytes, and phagocytes. It cleaves plasminogen to plasmin and hence stimulates fibrinolysis. Urokinase breaks down the matrix protein within the stone and thus prevents stone formation and growth. Urokinase concentrations are lower and urokinase gene 3′-UTR T/C polymorphism is higher in patients with recurrent stones. Our aim was to investigate the role of urokinase gene 3′-UTR T/C polymorphism in childhood recurrent stone disease. Material and methods: A control group of 40 healthy children having no history of stone formation (group 1) (mean age 10.5 ± 4.2 years), 40 children (mean age 10.5 ± 4.33 years) who had calcium oxalate stones for the first time (group 2), and 40 patients (mean age 11.2 ± 3.8 years) with recurrent calcium oxalate stone disease (group 3) were included in the study. The groups were compared with respect to age, gender and urokinase gene 3′-UTR T/C polymorphism. Polymerase chain reaction-based restriction analysis was used to identify C/T polymorphism of the urokinase gene. Results: No significant difference was observed between the three groups with respect to age and gender, while urokinase gene 3′-UTR T/C gene polymorphism was observed in four patients (10%) from group 3. In groups 1 and 2 there was no patient with T/C polymorphism. Conclusions: Urokinase 3′-UTR T/C gene polymorphism seems to appear more commonly in children with recurrent calcium oxalate stone disease than in healthy children and in those with stones for the first time. These results suggest that the urokinase gene might play a role in childhood recurrent calcium oxalate stone disease.Item Association of urokinase gene 3'-UTR T/C polymorphism with recurrent urolithiasis in children(Elsevier, 2007-03) Öztürk, Murat; Kordan, Yakup; Yavaşçaoglu, İsmet; Doǧan, Hasan Serkan; Kılıçarslan, Hakan; Vuruşkan, Hakan; Oktay, Bülent; Uludağ Üniversitesi/Tıp Fakültesi/Üroloji Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Tıbbi Genetik Anabilim Dalı.; 56781010900; 9633365800; 8911611600; 7005856022; 56007473800; 6507328150; 6602172127Item Association of vitamin D receptor gene Taq I polymorphism with recurrent urolithiasis in children(International Journal of Urology, 2007-12) Seyhan, Serkan; Yavaşçaoğlu, İsmet; Kılıçarslan, Hakan; Doğan, Hasan S.; Kordan, Yakup; Uludağ Üniversitesi/Tıp Fakültesi/Üroloji Bölümü.; ABH-5513-2020; 23009955000; 6603612497; 56007473800; 7005856022; 9633365800Objective: Urolithiasis has a strong familial component. However, to date, no specific genetic abnormality has been identified. It has been reported that allelic variation in the vitamin D receptor (VDR) gene may affect calcium absorption and excretion. Urolithiasis is a multifactorial disease in which both genetic and environmental factors have an effect on onset and severity of disease. In the present study, the role of Taq I polymorphism of vitamin D receptor gene in urolithiasis was studied. Methods: Eighty children with calcium stone disease (40 with single episode of stone disease and 40 with recurrence) and 40 controls were enrolled. Polymorphic sites were amplified by polymerase chain reaction, digested with Taq I restriction enzymes and analyzed by gel electrophoresis. Allelic or genotypic frequencies were calculated and associations between them and the presence of hypercalciuria, family history and stone recurrence were evaluated. Results: Incidence of Taq I tt genotypes was significantly higher in patients with recurrent calcium-stone disease compared to the controls. In addition, the frequency of the 't' allele was higher in recurrent calcium-stone formers. Taq I t allele was found to be associated with increased risk of recurrence. No association between Taq I polymorphism and a positive family history was found in the present study. The frequency of hypercalciuria was higher in patients with the 'tt' genotype. Conclusion: Taq I t allele of the VDR gene may be a risk factor for severe urolithiasis and recurrent stone disease.Item Cardiac and caval invasion of left adrenocortical carcinoma(Karger, 2008) Yavaşçaoǧlu, İsmet; Yılmaz, Mert; Kordan, Yakup; Uludağ Üniversitesi/Tıp Fakültesi/Üroloji Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Kalp Damar Cerrahisi Anabilim Dalı.; 6603612497; 57220839864; 9633365800Adrenocortical carcinoma (ACC) is a rare and highly malignant neoplasm. We present the case of a 51-year-old male patient with a left-sided ACC admitted to hospital with ipsilateral flank pain, weight loss, difficulty in breathing, abdominal discomfort and swelling and bilateral leg edema. Thoracoabdominal computed tomography revealed a huge adrenal mass with obvious tumor thrombus involvement of the inferior vena cava and right atrium. This is the first report describing caval and opposite side renal vein invasion of a left-sided ACC treated with grafting of the vessels. Histopathological examination of the tumors confirmed the diagnosis of ACC. Postoperative recovery was uneventful. The patient received an adrenolytic agent, mitotane, postoperatively and is alive with no evidence of recurrence after 2 years of follow-up.Publication Challenging risk factors for right and left laparoscopic adrenalectomy: A single centre experience with 272 cases(Brazilian Soc Urol, 2019-07-01) Kordan, Yakup; Günseren, Kadir Ömür; GÜNSEREN, KADİR ÖMÜR; Çiçek, Mehmet Cağatay; ÇİÇEK, MEHMET ÇAĞATAY; Vuruşkan, Hakan; VURUŞKAN, HAKAN; Yavaşçaoğlu, İsmet; YAVAŞCAOĞLU, İSMET; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Üroloji Anabilim Dalı.; 0000-0001-8673-3093; 0000-0002-0471-5404; 0000-0002-9947-848X; ABC-9924-2020Purpose: This study aimed to compare perioperative and postoperative results of right and left laparoscopic adrenalectomy (LA), and to evaluate the impact of challenging factors on these outcomes.Materials and Methods: A total of 272 patient's medical records that underwent single side LA between October 2006 and September 2017 were retrospectively reviewed. The patients were divided into 2 groups according to operation side. Moreover, pheochromocytoma, metastatic masses and adrenal lesions >5cm in size were considered to be difficult adrenalectomy cases and the outcomes of these cases were compared between two groups.Results: 135 patients (49.6%) underwent right LA and 137 patients (50.4%) underwent left LA. Operation time, estimated blood loss (EBL) and hospitalization time were similar between the groups (p=0.415, p=0.242, p=0.741, respectively). Although EBL was higher on the right side than the left (p=0.038) in the first 20 cases, after this learning period has been completed, there was no significant difference between the groups. In patients with pheochromocytoma, metastatic mass and a mass >5cm in size, despite bleeding complications were clinically higher on the right side, this difference was not statistically significant.Conclusions: During the learning period of LA, EBL is higher on the right side. Due to the greater risk of bleeding complications on the right side even on the hands of experienced surgeons, extra care and preoperative planning are required in patients with pheochromocytoma, metastatic masses and masses >5cm in size.Item Comparison of intermediate- and low-frequency shock wave lithotripsy for pediatric kidney stones(Springer, 2018-08) Kaygısız, Onur; Kılıçarslan, Hakan; Mert, Ahmet; Coşkun, Burhan; Kordan, Yakup; Uludağ Üniversitesi/Tıp Fakültesi/Üroloji Anabilim Dalı.; 0000-0002-9790-7295; AAM-9726-2020; L-9439-2019; JCO-5169-2023; AAH-9704-2021; 16637252400; 56007473800; 57195237287; 36113105900; 9633365800The aim of the study to compare low and intermediate shock wave frequency rates in terms of success and complications for treating pediatric kidney stones. This retrospective study was performed on 58 consecutive pediatric patients (24 girls, 34 boys) who underwent shock wave lithotripsy (SWL) for kidney stones with an electrohydraulic lithotripter between April 2014 and March 2016. In the first year, all children underwent SWL with a frequency of 90 SWs/min as an intermediate frequency (Group 90), and in the second year all children were treated by SWL using 60 SWs/min as a low frequency (Group 60). The mean age of the patients was 5.87 +/- 4.5 years. There were no significant differences in age, gender, stone characteristics and SWL energy level between the groups. Stone-free status was achieved in 14, 6 and 4 children in group 60; and in 10, 6 and 4 children in group 90 after one, two and three sessions, respectively. The stone-free rates were 80 and 74.1% after SWL and 90 and 88.9% after additional treatment in groups 60 and 90, respectively. The total median shock pulses were 2000 and 3600 in groups 60 and 90, respectively (p = 0.115). Efficiency quotients were 51.93 and 44.47 in groups 60 and 90, respectively. The mean total anesthesia times and complication rates did not differ between the groups. The low and intermediate frequency of SWL provided similar stone clearance in pediatric renal stones with similar anesthesia times. However, low SWL tended to need fewer shock pulses (2000/3600) for stone clearance, but the trend was not significant.Item Comparison of satisfaction rates in patients treated with malleable and 2-piece inflatable penile prothesis implantation(Elsevier, 2014-01) Kılıçarslan, H.; Kordan, Yakup; Coşkun, Burhan; Günseren, O.; Kaygısız, Onur; Serin, Onur; Yavaşçaoğlu, İsmet; Uludağ Üniversitesi.; 0000-0002-9790-7295; AAM-9726-2020; JCO-5169-2023Item Comparison of the effect of anastomosis type on early graft functions and complications in kidney transplant patients with multiple arteries(Oxford University, 2017-05) Sönmez, Aykut; Kordan, Yakup; Kaygısız, Onur; Coşkun, Burhan; Vuruşkan, Hakan; Yıldız, Abdülmecit; Oruç, Ayşegül; Ayar, Yavuz; Aydın, Mehmet Fethullah; Ersoy, Alparslan; Uludağ Üniversitesi/Tıp Fakültesi/Nefroloji Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Üroloji Anabilim Dalı.; 0000-0003-4607-9220; 0000-0002-0710-0923; 0000-0002-9790-7295; 0000-0002-5665-7402; O-9948-2015; AGF-0767-2022; AAH-9704-2021; GSE-0029-2022; AAH-4002-2021; AAH-5054-2021; AAM-9726-2020; AAJ-8220-2020Publication Comparison of ureteroscopic laser lithotripsy with laparoscopic ureterolithotomy for large proximal and mid-ureter stones(Karger, 2015-01-01) Kaygısız, Onur; Coşkun, Burhan; Kılıçarslan, Hakan; Kordan, Yakup; Vuruşkan, Hakan; Özmerdiven, Gökhun; Yavacaoğlu, İsmet; KAYGISIZ, ONUR; COŞKUN, BURHAN; KILIÇARSLAN, HAKAN; Kordan, Yakup; VURUŞKAN, HAKAN; Özmerdiven, Gökhun; Yavacaoğlu, İsmet; Uludağ Üniversitesi/Tıp Fakültesi/Üroloji Bölümü; 0000-0002-9790-7295; 0000-0002-8242-9921; 0000-0002-9947-848X; AAH-9704-2021; L-9439-2019; JCO-5169-2023; AAM-9726-2020; JIT-9412-2023; GAF-0095-2022; EFH-9523-2022; JIF-9579-2023; EIN-0828-2022Objectives: To compare the effectiveness and complications of ureteroscopic laser lithotripsy with laparoscopic ureter laparoscopic ureterolithotomy in mid- or proximal portion of large ureteral stones. Material and Methods: We reviewed patients with large (>15 mm) ureteral stone and those who underwent ureteroscopic laser lithotripsy CURS group) or laparoscopic ureterolithotomy (LU group). The first attempt was considered successful in patients who had residual fragments smaller than 2 mm and no conversion of the primary procedure to another. Results: Sixty patients (URS group 29, LU group 31) met inclusion criteria. FURS was used as an adjunctive procedure in one patient for URS group and in two patients for LU group in the same season. LU had a higher success rate and the first-day stone-free rate when compared with URS. Number of procedures was also significantly higher in URS group. There was no difference in stone-free rates at the first and third months, and length of hospitalization and operation were higher in the LU group. Only two patients in the LU group and one patient in the URS group had major complications. Conclusions: Laparoscopy is an effective option of large proximal and mid-ureter stone treatment; however, URS provides similar stone-free rates at three months as a minimal invasive procedure.Item Distal hipospadias olgularında ideal cerrahi tedavi(Uludağ Üniversitesi, 2005-05-27) Çalışkan, Zülküf; Vuruşkan, Hakan; Küçük, Muaffak; Kordan, Yakup; Yavaşçaoğlu, İsmet; Oktay, Bülent; Uludağ Üniversitesi/Tıp Fakültesi/Üroloji Anabilim Dalı.Çalışmanın amacı distal hipospadiasta uygulanan TIPU (Snodgrass), Mathieu ve MAGPI cerrahi yöntemlerinin başarı ve komplikasyon oranlarını kıyaslayarak, ideal cerrahi yöntemi belirlemektir. 1994-2003 yılları arasında kliniğimizde TIPU, Mathieu ve MAGPI yöntemiyle primer hipospadias onarımı uygulanan distal yerleşimli 60 hipospadias olgusu retrospektif olarak incelendi. TIPU (GrupI) Mathieu (GrupII) ve MAGPI (GrupIII) cerrahi yöntemiyle hipospadias onarımı uygulanan grupların herbirine preop ve postoperatif ampisilinsulbaktam 50mg/kg dozunda uygulandı. Olguların hastanede yatış süreleri, erken ve geç postoperatif komplikasyonlar ile, üretral kateter kalış süreleri ve üriner enfeksiyon oranları retrospektif olarak karşılaştırıldı. 60 olgunun gruplara göre dağılımı, grup I’de 25, grup II’de 22 ve grup III’de 13 olarak belirlendi. Grup I, II ve III’deki hastaların ortalama yaşları sırasıyla; 5 yaş, 11yaş, 6 yaş olarak saptandı. Olguların hastanede ortalama kalış süresi sırasıyla 3 gün, 5gün, 4gün olarak saptandı. Kateter kalış süreleri 5 gün, 7 gün ve 8 gündü. Olgular ortalama 4.5yıl takip edildi. Grup I’deki olgularda 1 (%4) cilt altı hematomu, 1 (%4) üretrokutanöz fistül, 1 (%4) meatal stenoz, 1 (%4) üretral stenoz ve 1 (%4) üriner enfeksiyon saptandı. Grup II’deki olgularda; 1 (%4.5) yara enfeksiyonu, 1 (%4.5) cilt altı hematomu, 2 (%9) üretrokutanöz fistül, 1 (%4.5) üretral stenoz ve 2 (%9) üriner enfeksiyon saptandı. Grup III’de 1 (%7.6) yara enfeksiyonu, 1 (%7.6) meatal stenoz, 2 (%15.3) penil deformite ve 1 (%7.6) üriner enfeksiyon saptandı. Distal hipospadias olgularında, kozmetik ve genel komplikasyon oranları açısından bakıldığında en ideal tedavi seçeneği TIPU’dir.Item Effect of ADMA levels on severity of erectile dysfunction in chronic kidney disease and other risk factors(Canadian Urological Association, 2016) Gokçen, Kaan; Kılıçarslan, Hakan; Coşkun, Burhan; Ersoy, Alparslan; Kaygısız, Onur; Kordan, Yakup; Uludağ Üniversitesi/Tıp Fakültesi/Üroloji Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Nefroloji Anabilim Dalı.; 0000-0002-9790-7295; 0000-0002-0710-0923; AAM-9726-2020; L-9439-2019; AAH-9704-2021; AAH-5054-2021; 56007473800; 57140828400; 35612977100; 16637252400; 9633365800Introduction: Hormonal, neurogenic, vasculogenic, and psychogenic impairments, as well as endothelial dysfunction may play a role in erectile dysfunction (ED) in patients with chronic kidney disease (CKD). Asymmetrical dimethylarginine (ADMA) is an inhibitor of nitric oxide, which is the key element of ED. ADMA levels are increased in CKD. We aimed to evaluate the effect of serum ADMA, prolactin, testosterone, and hemoglobin levels on erectile function of patients with CKD and control subjects. Methods: A total of 42 men with CKD and 25 age-matched controls were enrolled. The patients with CKD were categorized into group 1 and group 2 based on whether they had ED according to their response to International Index of Erectile Function questionnaire (IIEF-EFD). Group 3 was a control group. Serum ADMA, total testosterone prolactin, and hemoglobin levels of the patients were evaluated. Results: Serum ADMA, testosterone, and hemoglobin levels were similar between group 1 and 2, serum prolactin level was significantly high in group 1 than in group 2 or 3 (control group). There was no correlation between ADMA levels and IIEF-EFD scores of patients with CKD. Conclusions: The results of this study suggest serum ADMA level is not related with ED in patients with CKD. Also, low testosterone and hemoglobin levels were not significant factors. High levels of serum prolactin are related with ED in patients with CKD.Item The effect of renal arterial anastomosis techniques on the development of complications and graft dysfunction in recipients after kidney transplantation(Oxford University, 2017-05) Kanat, Fevzi Mutlu; Kordan, Yakup; Kaygısız, Onur; Coşkun, Burhan; Vuruşkan, Hakan; Oruç, Ayşegül; Yıldız, Abdulmecit; Ayar, Yavuz; Ersoy, Alparslan; Uludağ Üniversitesi/Tıp Fakültesi/Nefroloji Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Üroloji Anabilim Dalı.; 0000-0002-0710-0923; 0000-0003-4607-9220; 0000-0003-4607-9220; 0000-0003-4607-9220; 0000-0002-9790-7295; AAH-5054-2021; GSE-0029-2022; O-9948-2015; AAH-9704-2021; AGF-0767-2022; AAH-4002-2021; AAM-9726-2020Item Efficacy of levobupivacaine infiltration to nephrosthomy tract in combination with intravenous paracetamol on postoperative analgesia in percutaneous nephrolithotomy patients(Mary Ann Liebert, 2011-06) Gökten, Özgür Elvan; Kılıçarslan, Hakan; Doǧan, Hasan Serkan; Türker, Gürkan; Kordan, Yakup; Uludağ Üniversitesi/Tıp Fakültesi/Üroloji Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Anesteziyoloji ve Reanimasyon Anabilim Dalı.; 0000-0002-3019-581X; AAI-6642-2021; ABH-5513-2020; 35264184500; 56007473800; 7005856022; 7003400116; 9633365800Purpose: To evaluate the efficacy of intraoperative local anesthetic infiltration in combination with intravenous paracetamol infusion on postoperative pain management in patients who underwent percutaneus nephrolithotomy (PCNL). Patients and Methods: Sixty adult patients were randomized into three groups with 20 cases in each: Group SP, 20mL saline was infiltrated through the whole nephrostomy tract intraoperatively and this was followed by intravenous paracetamol (4 x 1 g) infusion postoperatively; group LP, 20mL of 0.25% levobupivacaine infiltration to the nephrostomy tract followed by intravenous paracetamol infusion; Group LS, 20mL of 0.25% levobupivacaine infiltration to the nephrostomy tract followed by intravenous saline infusion. In the postoperative period, the pain status of patients was evaluated at postoperative 6 and 24 hours by using the visual analogue scale (VAS). In patients who did not completely respond, meperidine (1mg/kg intramuscularly) was administered as an additional "rescue'' analgesic. Patient satisfaction from the postoperative analgesia management was assessed by a 5 point scale. Results: There was no statistically significant difference between the three groups regarding the demographic characteristics, surgical complications, and postoperative hospital stay. Our findings revealed that in group LP, the amount and frequency of opioid used and related side effects was lesser, VAS score was lower, time to full mobilization was shorter, and the patient satisfaction score was higher when compared with the other two groups. Conclusion: Levobupivacaine infiltration through the nephrostomy tract in combination with intravenous paracetamol infusion was shown to be safe and efficacious as an analgesia method after PCNL.Item Elevated plasma concentrations of transforming growth factor-beta 1 in patients with unilateral ureteral obstruction(Springer, 2005-12) Vuruşkan, Hakan; Çalışkan, Zulüf; Özakın, Cüneyt; Yavasçaoğlu, İsmet; Oktay, Burçin; Kordan, Yakup; Uludağ Üniversitesi/Tıp Fakültesi/Üroloji Bölümü.; Uludağ Üniversitesi/Tıp Fakültesi/Mikrobiyoloji Bölümü.We measured plasma concentrations of TGF-beta 1 in patients with obstructive ureteral calculi and compared them with the plasma concentrations of healthy volunteers. The present study was a prospective study containing a homogenous group of patients with unilateral ureteral obstruction (UUO). The study consisted of patients with ureteral stones less than 7 mm in diameter that caused mild to moderate obstruction. All patients were referred by the emergency department of our hospital and examined between April 2003 and April 2004. The presence and characteristics of both stone and obstruction were determined by plain abdominal x-ray and gray-scale ultrasonography (US). Blood samples were collected from both patients and control individuals on admission and 1 week after conservative follow-up. The plasma TGF-beta 1 concentration was determined using a quantitative sandwich enzyme immunoassay specific for TGF-beta 1. There were 35 patients with 20 women and 15 men (average age 26.8 +/- 5.9 years), and 15 volunteers in the control group, with nine women and six men (average age 24.2 +/- 4.5 years). Average stone size was 5.6 mm +/- 1.2 mm (range 3.5-7) for the patient group. US showed the presence of mild hydronephrosis in 24 and moderate hydronephrosis in 11 patients. Plasma concentrations of TGF-beta 1 in patients with ureteral obstruction (1,117 +/- 5.8 ng/ml, range 36-2,442 ng/ml) were significantly higher than those in the healthy control group (32 +/- 4 ng/ml) on admission (P < 0.001). There was a significant increase in TGF-beta 1 plasma concentrations in the patient group (33,525 +/- 6.8 ng/ml, range 1,107-73,288 ng/ml) after 1 week follow-up (P < 0.001). Ureteral obstruction increases plasma TGF-beta 1 concentrations in patients with ureteral stones as in UUO models in animal studies. A concomitant treatment with an anti-fibrotic agent may reduce the incidence of renal injury during obstruction.Item Evaluation of the relationship between asymmetric dimethylarginine (adma) and severity of erectile dysfunction in chronic renal failure(Elsevier, 2014-01) Kaygısız, Onur; Gökçen, Kaan; Coşkun, Burhan; Açıkgöz, H. E.; Kordan, Yakup; Serin, Onur; Kalacarslan, H.; Uludağ Üniversitesi.; 0000-0002-9790-7295; 0000-0002-9790-7295; JCO-5169-2023; AAM-9726-2020; AAH-9704-2021; L-9439-2019Item F-18-FDGPET/CT in the evaluation of adrenal masses in patients with oligometastatic state non-small cell lung cancer: A histopathologic comparison after laparoscopic adrenalectomy(Springer, 2016) Kordan, Yakup; Şen, Feyza; Kaygısız, Onur; Özmerdiven, Gökhun; Yavaşcaoğlu, İsmet; Uludağ Üniversitesi/Tıp Fakültesi/Üroloji Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Nükleer Tıp Anabilim Dalı.; 0000-0002-9790-7295; L-9439-2019; AAM-9726-2020Publication Factors influencing lymphocel development after kidney transplantation: Single center experience(Oxford University Press, 2015-05-01) Sayılar, Emel Işıktaş; Ersoy, Alparslan; Ayar, Yavuz; Aydın, Mehmet Fethullah; Şahin, Ahmet Bilgehan; Coşkun, Burhan; Kaygısız, Onur; Yıldız, Abdulmecit; Kordan, Yakup; Vuruşkan, Hakan; SAYILAR, EMEL IŞIKTAŞ; ERSOY, ALPARSLAN; AYAR, YAVUZ; AYDIN, MEHMET FETHULLAH; ŞAHİN, AHMET BİLGEHAN; COŞKUN, BURHAN; KAYGISIZ, ONUR; YILDIZ, ABDULMECİT; KORDAN, YAKUP; VURUŞKAN, HAKAN; 0000-0003-4607-9220; 0000-0002-5665-7402; 0000-0002-7846-0870; 0000-0002-8242-9921; 0000-0002-9790-7295; 0000-0002-9947-848X; 0000-0002-0710-0923; AAH-5054-2021; O-9948-2015; L-9439-2019; JCO-5169-2023; AAH-9704-2021; AGF-0767-2022; AAJ-8220-2020; AAM-4927-2020; GSE-0029-2022; W-2575-2017; AAM-9726-2020; HIG-9032-2022; GAF-0095-2022; EFH-9523-2022Publication Factors influencing lymphocele development after kidney transplant: Single center experience(Başkent Üniversitesi, 2023-03-01) Sayılar, Emel Işıktaş; Ersoy, Alparslan; Ayar, Yavuz; Aydın, Mehmet Fethullah; Şahin, Ahmet Bilgehan; Coşkun, Burhan; Kaygısız, Onur; Yıldız, Abdülmecit; Kordan, Yakup; Vuruşkan, Hakan; Sayılar, Emel Işıktaş; ERSOY, ALPARSLAN; Ayar, Yavuz; Aydın, Mehmet Fethullah; ŞAHİN, AHMET BİLGEHAN; COŞKUN, BURHAN; KAYGISIZ, ONUR; YILDIZ, ABDULMECİT; Kordan, Yakup; VURUŞKAN, HAKAN; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Nefroloji Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/İç Hastalıkları Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Üroloji Anabilim Dalı.; 0000-0003-4607-9220; 0000-0002-5665-7402; 0000-0002-7846-0870; 0000-0002-8242-9921; 0000-0002-9790-7295; 0000-0002-9947-848X; AAJ-8220-2020; O-9948-2015; AAH-9704-2021; L-9439-2019; JCO-5169-2023; AAM-4927-2020; HYA-4372-2023; CPX-5894-2022; HIG-9032-2022; GAF-0095-2022; EFH-9523-2022Objectives: Lymphocele is a well-known postoperative surgical complication after kidney transplant. In this study, our aim was to analyze incidence, risk factors, and outcomes of posttransplant lymphocele in a large cohort.Materials and Methods: This observational study included 395 consecutive patients (219 males and 176 females) who underwent kidney transplant procedures from 183 living and 212 deceased donors in our center between January 2007 and 2014. A lymphocele was diagnosed with ultrasonography.Results: The incidence of lymphoceles in our cohort was 31.9% (n = 126). There were no significant differences with regard to body mass indexes, age of donors, deceased donor ratios, acute rejection episodes, and history of abdominal surgery between those with and without lymphoceles. The pretransplant serum albumin levels (3.29 +/- 0.67 vs 3.48 +/- 0.69 g/dL; P = .009) in the lymphocele group and diabetes mellitus ratios (15.9% vs 4.5%; P < .001) in the nonlymphocele group were lower than levels shown in the other group. The lymphocele ratio in patients who received cyclosporine was higher than that shown in patients who did not received it (37.5% vs. 27.4%; P = .032). There was no difference in lymphocele incidence between patients who were taking and those who were not taking mammalian target of rapamycin inhibitors, mycophenolate mofetil, or mycophenolate sodium. In regression analysis, presence of diabetes mellitus, transplant from deceased donors, older age of donors, and lower albumin levels were independent risk factors for posttransplant lymphocele occurrence.Conclusions: Posttransplant lymphocele was a relatively common surgical complication in our cohort. We concluded that diabetes mellitus, use of kidneys from deceased donors, older donor age, and hypoalbuminemia were independent risk factors for lymphocele development.Publication How should be follow-up strategy in stage 1 testicular tumor, are there any novelties?(Galenos Yayincilik, 2011-09-01) Kordan, Yakup; Çiçek, Mehmet Cağatay; ÇİÇEK, MEHMET ÇAĞATAY; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Üroloji Anabilim Dalı.; 0000-0002-9947-848X; 0000-0002-0471-5404Testicular germ cell tumors are the most common cause of cancer in men between the age of 15 and 45 years and most patients have stage 1 disease at presentation. Although well defined clinical guidelines are present for the diagnosis and the treatment of testicular carcinoma there is not enough study published on the ideal follow-up of patients with stage 1 testicular carcinoma. An ideal follow-up protocol should not only provide early detection and treatment of recurrences but also ensure identification and reduction of side effects and secondary malignancies due to treatment. Besides, it should be economically feasible. In this article, the current literature and novelties regarding ideal follow-up for stage 1 testicular carcinoma were reviewed.Item Laparoscopic adrenalectomy: Uludag University experience(Mary Ann Liebert, 2012-09) Özmerdiven, Çağdaş Gökhun; Kordan, Yakup; Vuruşkan, Hakan; Doğan, Hasan Serkan; Gökçen, Kaan; Yavaşçaoğlu, İsmet; Uludağ Üniversitesi/Tıp Fakültesi/Üroloji Anabilim Dalı.; ABH-5513-2020
- «
- 1 (current)
- 2
- 3
- »