Browsing by Author "Shahsavani, Davar"
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Item Biochemical alterations induced by sublethal cyanide exposure in common carp (Cyprinus carpio)(Uludağ Üniversitesi, 2013-06-25) Sadati, Fahimeh; Shahsavani, Davar; Baghshani, HasanThe present study was designed to study the effects of sublethal cyanide exposure on some blood biochemical parameters in common carp. Three groups of fish (25 in each group) were treated with different concentrations of 0 (control), 0.1 or 0.2 mg/L potassium cyanide (KCN) for 2 weeks. At the end of each exposure, blood samples were collected and serum biochemical parameters were measured using validated methods. Cyanide exposure at both concentrations caused significant (P<0.05) elevation of aspartate aminotransferase and lactate dehydrogenase activities and creatinine concentration as compared to control group. Indeed, alanine aminotransferase, alkaline phosphatase and glucose levels in the carp treated with 0.2 mg/L KCN were significantly higher than those levels from controls. On the other hand, other measured biochemical parameters including gamma-glutamyl transferase, triglyceride, cholesterol, total protein, and albumin did not change significantly following cyanide exposure. The observed alterations in some measured serum biochemical parameters would reflect tissue damages, especially in liver and kidney, due to chronic cyanide intoxication in common carp and may be used for better understanding the pathophysiology of this toxicity and as an aid in the diagnosis of cyanide poisoning in fish species.Publication Effect of supplementation with lemon (Citrus lemon) pomace powder on the growth performance and antioxidant responses in common carp (Cyprinus carpio)(Bursa Uludağ Üniversitesi, 2021-09-08) Laein, Sara Safaeian; Salari, Amir; Shahsavani, Davar; Baghshan, HasanThis study was aimed to investigate beneficial effects of lemon pomace powder (peel and pulp), on growth performance and antioxidant responses in common carp. Fish were divided randomly into four groups of 30 each. Group 1 fish were fed with basic diet, serving asthe control. Fish in group 2, 3 and 4 were fed the basic diet supplemented with 1.5%, 3% and 5% lemon pomace powder, respectively. Results showed that the values of glutathione peroxidase (GPX), superoxide dismutase (SOD) and glutathione peroxidase (GSH) inerythrocyte hemolysate were significantly increased in all of the treatment groups compared with the control (P<0.05). Significantly lower level of plasma malondialdehyde (MDA) concentrations were observed in fish receiving 5% lemon powder. Ferric reducing antioxidant power (FRAP) values increased significantly as compared to control and the most increase was observed in group 4 whichreceived 5% lemon pomace. No significant differences were found in plasma values of total protein, albumin, bilirubin, urea, lactatede hydrogenase, alkaline phosphatase, alanine aminotransferase and aspartate aminotransferase among the experimental groups. Fishthat were fed diet supplemented with 3% and 5% of lemon pomace powder displayed improved growth performance including final weight, weight gain, feed conversion ratio and specific growth rate. These data suggest that supplementation of lemon pomace powder can be effective in improving the antioxidant capacity and growth performance in common carp.