1986-1987 Cilt 5-6 Sayı 1-2-3

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Nitrat ve nitrit'in farelerde immunosupresif etkileri üzerinde araştırmalar
(Uludağ Üniversitesi, 1987) Kahraman, Mustafa; Veteriner Fakültesi; Mikrobiyoloji Ana Bilim Dalı
Eighty white mice, which were a month of age, were divided into four equal numbered groups and were fed for six months under the same circumstances. During this period 400 mg/lt of NaN02 and NaN03 were added into the drinking water of third and {ourth groups, respectively . At the end of six months, all groups except for the first one were injected Hitchner B1 (10 /D/0.25 ml) of Newcastle virus (NV) by way of subcutan three times at one day intervals. Fifteen days after the last injection blood was taken from all the animals in separate groups;serums were prepared arıd examined by means of Hemagglutination-inhibition (H tests. Asa result, the tillers of the four different groups were found to be 2- l , 2- , 2- 5 and 2 -4 HI tilers respectively. Meanwhile, immunosuppressive effect was observed in the third and {ourth groups, into whose drinking water nitrite and nitrate were added.