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Publication Abrasion resistance and tensile strength of chenille and macaroni upholstery fabrics(Ege Üniversitesi, 2011) Tekoǧlu, Onur; Kavuşturan, Yasemin; Uludağ Üniversitesi/Mühendislik Fakültesi/Tekstil Mühendisliği Bölümü.; 0000-0002-9919-564X; A-7462-2018; 24824357200In this study, an experimental work is. presented to determine the effects of two different fancy yarn structures (chenille and macaroni) and four different raw materials (acrilic, cotton, polyester and viscose) on the abrasion and tensile propertries of woven upholstery fabrics. Results were evaluated by SPSS statistical program. All test results were assessed at a confidence level of at least 95% (at most 5% significance level). The abrasion resistance and tenacity values of chenille and macaroni yarns were measured too. Abrasion resistance and tenacity values of chenille and macaroni yarns are affected significantly by material type and fancy yarn structure. Macaroni yarns show higher. weight loss (%) ratio and tenacity values than chenille yams. Thickness values of chenille fabrics are higher than macaroni fabrics. Weight loss (%) values of chenille fabrics are higher than macaroni fabrics. The macaroni fabrics show higher stress values at max. load than chenille fabrics. The cotton and polyester yarns. are abraded less than others. Polyester yams and fabrics show the highest tensile strength values. Viscose yarns and fabrics less resistant to abrasion.Publication Analysis of effects of Young modulus variations on Brillouin power and Brillouin frequency shift changes in optical fibers(Natl Inst Optoelectronics, 2016-11-25) Günday, Abdurrahman; Karlık, Sait Eser; Yılmaz, Güneş; Uludağ Üniversitesi/Orhangazi Meslek Yüksekokulu/Elektronik Teknolojisi Programı.; Uludağ Üniversitesi/Mühendislik Fakültesi/Elektrik-Elektronik Mühendisliği Bölümü.; AAH-5448-2021; AAJ-2404-2021; 55747963900; 10043513300; 6504559945Brillouin scattering mechanism and Young modulus variations in optical fiber distributed sensing systems are directly affected by ambient temperature and thermal strain formations. Generally, in such sensing systems where temperature and strain formations are detected and measured simultaneously, Brillouin frequency shift and Brillouin power changes of backscattered optical signal are used due to their temperature and strain dependencies. In this research, a different point of view has been developed and effects of Young modulus variations of the sensing fiber core on the Brillouin power and the Brillouin frequency shift changes have been analyzed. In this study, positioning five heating units at different locations along a 1000 m G.652 type single-mode fiber operating at 1550 nm, a sensing system model has been constructed. On this model, simulations related to Young modulus variations along the sensing fiber depending on temperature fluctuations generated by heating units have been performed using Matlab 2010 and results have been obtained for 1000 different points with a spatial resolution of 1 m. For 40 degrees C- 47 degrees C operating temperature range of the sensing fiber, the Young modulus of the fiber core changes from 73.205 GPa to 73.283 GPa. Furthermore, using the analytical method, linear formula between the Young modulus and Brillouin parameters, i.e. Brillouin power and Brillouin frequency shift changes, of the backscattered optical signal have been derived. Thus, for the system model constructed, Matlab simulations analyzing relations between Young modulus variations and Brillouin parameter changes have been performed under specified operating conditions. For Young modulus variations in 73.205 GPa - 73.283 GPa range, values of Brillouin power and Brillouin frequency shift changes have been obtained in ranges of 13.950 % - 16.273 % and 69.00 MHz - 85.72 MHz, respectively. Moreover, temperature and thermal strain resolutions along the sensing fiber have been acquired as similar to 0.7 degrees C and similar to 40 mu epsilon, respectively.Publication Bounds for a new subclass of bi-univalent functions subordinate to the Fibonacci numbers(Scientific Technical Research Council Turkey, 2020) Altınkaya, Şahsene; Bursa Uludağ Üniversitesi/Fen-Edebiyat Fakültesi/Matematik.; 0000-0002-7950-8450; AAA-8330-2021; 56543332200In this investigation, by using a relation of subordination, we define a new subclass of analytic bi-univalent functions associated with the Fibonacci numbers. Moreover, we survey the bounds of the coefficients for functions in this class.Publication Bullying and school climate from the aspects of the students and teachers(Anı Yayıncılık, 2009) Kartal, Hülya; Bilgin, Asude; Uludağ Üniversitesi/Eğitim Fakültesi/Sınıf Eğitimi Anabilim Dalı.; AAW-8954-2020; 35339190200; 55793254000Problem Statement: School culture and school climate describe the environment that affects the behavior of teachers and students. School climate reflects the physical and psychological aspects of the school that are more susceptible to change and that provide the preconditions necessary for teaching and learning to take place. In addition, school climate is a significant element in discussions about improving academic performance. The most important component of school climate is safety. However, incidents of bullying are frequent occurrences for many children at school and in the community. Children who are bullied fear coming to school, and they believe school to be an unsafe and distressing place. Purpose of Study: The primary purpose of the present study is to investigate the feelings of both elementary students and their teachers about the school climate in terms of their perceptions of safety in the school. It is also of importance to describe the types and the prevalence of bullying, and possible incidents where bullying occurs, where they feel safe, and whom they tell about bullying. Methods: 688 students from the 4(th) through 8(th) grade from one elementary school and 58 randomly selected teachers were presented a questionnaire called the Colorado School Climate Survey. The data was analyzed in terms of frequencies and variance. Findings and Results: 41.3% reported that over the last month they were bullied at least once in a week or more. The results showed an average school climate scored 42.5 points out of a 56 point maximum. 25.4% of the students were found to be neither bullies nor victims. 41.3% of them were victims, 3.3% were bullies, and 29.9 % were bully-victims. Conclusion and Recommendations: Bullying is a serious problem in many schools and there seems to be no one single solution for every student. It is known, however, that the social context and supervision of the school play a major role in the frequency and severity of bullying problems.Publication A capillary polymerase chain reaction for Salmonella detection from poultry meat(Wiley, 2007-01) Günaydın, Elçin; Eyigör, Ayşegül; Çarlı, Kamil Tayfun; Uludağ Üniversitesi/Tıp Fakültesi/Mikrobiyoloji Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Besin Hijyeni ve Teknolojisi Anabilim Dalı.; E-3867-2010; AAI-1101-2021; 8350555600; 6602558950; 6601971539Aims: In this study, a capillary polymerase chain reaction (cPCR) was applied for Salmonella detection from poultry meat. Methods and Results: Salmonella detection limits of the optimized cPCR were determined with DNA templates from the samples of tetrathionate broth (TTB), Rappaport Vassiliadis broth (RVB) and selenite cystine broth (SCB) artificially contaminated with 10-fold dilutions of 6 x 10(8) CFU ml(-1) of pure Salmonella enterica ssp. enterica serovar Enteritidis 64K stock culture. Detection limits of cPCR from TTB, RVB and SCB were found as 6, 6 x 10(1) and 6 x 10(4) CFU ml(-1), respectively. In addition, detection limits of bacteriology were also determined as 6 CFU ml(-1) with TTB and SCB, and 6 x 10(1) CFU ml(-1) with RVB. A total of 200 samples, consisting of 100 chicken and 100 turkey meat samples, were tested with optimized cPCR and bacteriology. Eight and six per cent of the chicken meat samples were found to harbour Salmonella by cPCR and standard bacteriology, respectively. Of six Salmonella isolates, four belonged to serogroup D, two to serogroup B. Conclusions: The TTB cultures of both artificially and naturally contaminated samples were found to be superior to those of RVB and SCB cultures in their cPCR results. This cPCR, utilizing template from 18-h TTB primary enrichment broth culture, takes approximately 40 min in the successful detection of Salmonella from poultry meat. Significance and Impact of the study: This study shows that cPCR from TTB enrichment culture of poultry meat would enable rapid detection of Salmonella in laboratories with low sample throughput and limited budget.Publication Chloroquine in idiopathic pulmonary hemosiderosis - A case report(Türkiye Milli Pediatri Derneği, 1997) Meral, Adalet; Günay, Ünsal; Küçükerdoğan, Aygün; Canıtez, Yakup; Özuysal, Sema; Uludağ Üniversitesi/Tıp Fakültesi/Pediatri Anabilim Dalı.; 6602571317; 6603885274; 6508083721; 8988954700; 56616314600This report describes an 11-year-old boy with idiopathic pulmonary hemosiderosis. His only presenting symptom was severe anemia due to Iron deficiency. Idiopathic pulmonary hemosiderosis was diagnosed nine years after the onset of symptoms. During this period many invasive and non-contributory investigations were performed. This report describes the patient's diagnostic problems, clinical features and dramatic improvement with chloroquine (250 mg/day) after failing to respond to megadose methylprednisolone (30 mg/kg). One year later, chloroquine was discontinued. The patient has remained in remission since March 1994. Chloroquine should be used for this life-threatening conditon since a is less toxic than other immunosuppressive drugs.Publication Comparison of reboxetine and sertraline in terms of efficacy and safety in major depressive disorder(Türkiye Sinir ve Ruh Sağlığı Derneği, 2005) Akgöz, Semra; Eker, Salih Saygın; Akkaya, Cengiz; Kirli, Selçuk; Sarandöl, Aslı; Uludağ Üniversitesi/Tıp Fakültesi/Ruh Sağlığı ve Hastalıkları Anabilim Dalı.; Q-9477-2019; 14019347700; 14061855100; 14061863400; 14020405100; 14019745700Objective: To compare the efficacy, safety and tolerability of reboxetine and sertraline in major depressive disorder (MDD). Method: The study subjects consisted of 41 patients who met the DSM-IV MOD diagnostic criteria. Patients were randomly assigned to receive either reboxetine or sertraline. During the study the patients were assessed 6 times (baseline visit=day 0, visit 1=day 8, visit 2=day 22, visit 3=day 36, visit 4=day 57 and visit 5=day 78) over 11 weeks. Antidepressant response was measured by the Hamilton Depression Rating Scale (HORS), Clinical Global Impressions-Severity of Illness (CGI-SI) and Global Impressions-Global Improvement (CGI-GI). Results: Comparing the two groups in terms of response and remission (HAM-D <= 10) measures, the results were in favour of the reboxetine group at visits 2, 3 and 4. At visit 5, the scores were similar and no statistically significant difference was found between the two groups. However, when remission was evaluated as HAM-Df <= 7, a significant statistical difference was found in favour of the reboxetine group. Evaluating the side effects, dry mouth, sweating, palpitation, headache, hot flushing and sedation were more frequent in the reboxetine group. Only one patient, in the reboxetine group, dropped out due to a side effect (constipation). Conclusion: Higher rates of full remission achievement, which is the main target of MOD treatment, in the reboxetine group compared with the sertraline group may be due to the suppression of anxiety symptoms by the noradrenergic feature of the drug. In order to understand the role of the noradrenergic system in treating MDD, larger patient samples are needed. Both reboxetine and sertraline were well tolerated and effective in treating MDD.Publication A comparison of the scapular manipulation and Kocher's technique for acute anterior dislocation of the shoulder(Eklem Hastalıkları Tedavi Vakfı, 2011) Şahin, Namık; Öztürk, Alpaslan; Özkan, Yüksel; Atıcı, Teoman; Özkaya, Güven; Uludağ Üniversitesi/Tıp Fakültesi/Ortopedi ve Travmatoloji Anabilim Dalı.; Uludağ Üniversitesi/Sağlık Bilimleri Enstitüsü/Biyoistatistik Anabilim Dalı.; 0000-0003-0297-846X; A-5095-2018; A-4421-2016; 7801647288; 16316866500Objectives: The aim of the present study was to compare the scapular manipulation technique and the Kocher's method in terms of efficacy, safety, and the intensity of pain felt by the patient in the reduction of acute anterior shoulder dislocation. Patients and methods: Between July 2009 and January 2010, a total of 64 patients with acute traumatic anterior dislocation of the shoulder were evaluated. Of the 64 patients assessed, three patients were excluded because of cardiopulmonary problems. The remaining 61 patients (41 males, 20 females; mean age 42 +/- 18.5 years; range 17 to 87 years) were enrolled in this prospective randomized study and devided into two groups. Thirty-one patients were treated with scapular manipulation (group 1) and 30 patients were treated by the Kocher's method (group 2). A procedural sedation/analgesia was applied before the reduction to meet the target sedation score of 1 or 2 according to the Ramsay sedation scale. A visual analog scale was used to determine the intensity of the pain felt by the patients during reduction. Results: Reduction was successfully achieved with the scapular manipulation method in 96.7% of the patients, and with the Kocher's method in 93.3% (p>0.05). The degree of pain experienced by group 1 was lower than group 2 (p<0.01). Conclusion: Both scapular manipulation and Kocher's techniques are successful and reliable methods when procedural sedation/analgesia is used routinely. Scapular manipulation is a less painful method of reduction of an anterior shoulder dislocation in comparison with the Kocher's technique.Publication Determining the opinions of Preschool and primary school teacher candidates on creativity and metaphorical perception(Edam, 2012) Zeteroğlu, Elvan Şahin; Doğan, Yadigar; Derman, Meral Taner; Uludağ Üniversitesi/Eğitim Fakültesi/İlköğretim Bölümü.; 55489163800; 26656529900; 26656535200Aim of this research is to determine the opinions of teacher candidates about creativity and to reveal their perception of creativity concept through the use of metaphors. The data have been collected from 193 Preschool and Primary school teacher candidates and a survey, which had been prepared by researchers, has been used as the data-collecting tool. It is seen that teacher candidates see creativity as creating different, extraordinary, and genuine products. Teacher candidates see thinking skills, genuineness and innovation as features of a creative person. Teacher candidates think that not everybody can possess creativity and that it is an improvable and learnable feature. While it has been determined that there is a significant difference between gender, branch and the number of the books read in a year in respect of creativity, it is seen that 4th grade students have more positive opinions than other teacher candidates who are interested in painting.Publication Effect of genotypical factors on the effectiveness of anther culture in eggplant (Solanum melongena L.)(TÜBİTAK, 2013) Ellialtıoğlu, Şeküre Şebnem; Başay, Sevinç; Uludağ Üniversitesi/Karacabey Meslek Yüksekokulu.; 37460945300The aim of this study was to determine the androgenic capacity of some eggplant (Solanum melongena L.) varieties and breeding lines, and to establish the effectiveness of androgenesis induction in the less responsive genotypes by crossing with more responsive genotypes that have a high ability for haploid embryo formation. Flower buds containing greenish-yellow anthers were collected when the microspores were at the late uninucleate stage, which is equivalent to a bud size where petals are not visible. The anthers were kept in the dark at 35 degrees C for 8 days, then incubated with a 12 h light period at 25 degrees C for 4 days on C medium, and then transferred to solid R medium, supplemented with 30 g/L sucrose and 0.1 mg/L kinetin. Topan, Halep Karasi, and Teorem F-1 varieties and 2 breeding lines [Vd-1 and Vd-2 (LS 2346)] that have a tolerance to Verticillium dahliae Kleb. were used as the plant materials during the first part of the study. Haploid embryos were obtained from Topan and Halep Karasi at the rate of 4.16% and 2.63%, respectively. The responses of Topan and Halep Karasi eggplant varieties to the anther culture were better than those of the Teorem F-1 cultivar and the Vd-1 and Vd-2 lines. Because of their responses to anther culture, the Topan and Halep Karasi varieties were used as donor parents, and they were crossed with the other 3 genotypes (Teorem F-1, Vd-1, and Vd-2) reciprocally. Gametic embryogenesis among hybrids was only obtained from the Topan x Teorem F-1, and Teorem F-1 x Topan combinations (0.87% and 2.57%, respectively). Development of the haploid embryos and plant formation occurred at the rates of 0.69% and 2.57%, respectively. This study revealed that the effectiveness of androgenesis in eggplant strongly depended on genotypes. This crossing technique could be useful for increasing the opportunity for haploid embryogenesis from genotypes that are unlikely to form haploid embryos, and crossing between the fair-responsive and poor/nonresponsive genotypes could be a good system for qualifying androgenic response in eggplant.Publication Effect of presynchronization with prostaglandin F-2 alpha before the 5-d timed AI protocol on ovarian responses and pregnancy in dairy heifers(Elsevier, 2019-07-01) Karakaya, Ebru Bilen; Ribeiro, Eduardo S.; Bisinotto, Rafael S.; Santos, Jose Eduardo P.; Gümen, Ahmet; Bursa Uludağ Üniversitesi/Veteriner Fakültesi/Klinik Bilimler Anabilim Dalı.; AAH-1406-2021; 6602393069The objectives were the determine the effects of presynchronization with PGF(2)(alpha) 2 days before the 5-d timed artificial insemination (Al) protocol on ovarian responses and pregnancy per AI (P/AI) in dairy heifers. The hypothesis was that PGF(2)(alpha )m would induce responsive heifers to be in proestrus at the initiation of the timed Al protocol, which was expected to improve ovulatory responses and P/AI. Weekly cohorts of Holstein heifers were blocked by age and, within block, randomly assigned to remain as control (CON; n = 255) or receive PGF(2)(alpha) on experiment Day -10 (PG; n = 255). All heifers were subjected to the 5-d timed AI protocol (Day -8, GnRH + intravaginal progesterone controlled internal drug release insert; Day -3, PGF(2)(alpha) and insert removal; Day -2, PGF(2)(alpha); and Day 0, GnRH and AI). A subset of 22 blocks of heifers (n = 43) had their ovaries scanned by ultrasonography on experiment Days -8, -3, 0, and 2 and blood was sampled and analyzed for concentrations of progesterone on experiment Days -8, -7, -5, and -3. Pregnancy was diagnosed on experiment Days 32 and 60. On the day of the first GnRH of the timed AI protocol, PG heifers had smaller concentration of progesterone in plasma (CON = 4.5 +/- 0.5 vs. PG = 0.5 +/- 0.5 ng/mL), but larger follicular diameter (CON = 9.1 +/- 0.5 vs. PG = 11.0 +/- 0.5 mm), and a greater proportion of them had a follicle with at least 8.0 mm in diameter (CON = 61.9 vs. PG = 90.9%) than CON heifers, which resulted in increased ovulation to GnRH (CON = 19.0 vs. PG = 86.3%). Ovulation to the initial GnRH of the protocol increased as the concentration of progesterone in plasma decreased, from less than 20% when progesterone was greater than 5.0 ng/mL to more than 65% when progesterone was less than 1.0 ng/mL. More CON than PG heifers spontaenously ovulated before the day of timed AI. Detection of estrus on the day of timed AI did not differ between treatments (CON = 50.9 vs. PG = 46.6%), but P/AI on Days 32 (CON = 52.9 vs. PG = 61.1%) and 60 (CON = 49.0 vs. PG = 57.1%) after inseminationtended to be greater for PG than CON; however, the benefit to presynchronization was observed in heifers inseminated with conventional (CON = 54.7 vs. PG = 67.4%), but not in heifers inseminated with sex-sorted semen (CON = 50.9 vs. PG = 52.8%). Administration of PGF(2)(alpha) 2 days before initiating the timed AI protocol induced heifers to be in proestrus, which enhanced ovulation to the initial GnRH and favored pregnancy per AI, particularly in heifers inseminated with conventional semen.Publication The effectiveness of embedded teaching through the most-to-least prompting procedure in concept teaching to children with autism within Orff-based music activities(EDAM, 2013) Deniz, Jale; Düzkantar, Ayten; Eren, Bilgehan; Uludağ Üniversitesi/Eğitim Fakültesi/Müzik ve Güzel Sanatlar Bölümü.; JWP-0528-2024; 55795155300The purpose of this study was to demonstrate the effectiveness of embedded teaching through the most-to-least prompting procedure in concept teaching to children with autism in Orff-based music activities. In this research, being one of the single subject research designs, multiple probe design was used. The generalization effect of the research was assessed in the form of a pre-test and post-test, discussing the organization about interpersonal generalization in different environment. The maintenance of learning was checked by means of the observation sessions applied one, two, and four weeks after the practice was completed. The research was conducted with 3 children with autism between the ages of 3-6 in Nova Special Training and Rehabilitation Center in Istanbul. In research process, full probe, daily probe, teaching, observing and generalizing sessions have been organized. All of the sessions were done by one-to-one teaching method. The data of reliability among the observers and of application reliability were collected. According to research results, it was clear that the embedding teaching through the most-to-least prompting in Orff-based music activities is effective to teach concepts to the chilren with autism. It was understood that the maintenance was kept after the training was completed. It was also clear that the concept which was thought is effective in the generalization of different settings, different people and different materials. Additionally, social validity was verified in research to determine the importance of purposes of research, teaching methods to reach these purposes and research results.Publication The effects of computer simulated experiments on high school students' understanding of the displacement and velocity concepts(Anı Yayıncılık, 2010) Özden, M. Yaşar; Şengel, Erhan; Uludağ Üniversitesi/Eğitim Fakültesi/Bilgisayar ve Öğretim Teknolojileri Öğretmenliği Bölümü.; AAG-9156-2021; 35976882000The number of relationships between important concepts is higher in physics courses than in other courses. As well as the definitions of complicated concepts, the feature of concepts should be learned. Using traditional instructional methods are sometimes not enough to teach physics concepts like velocity and displacement. Based on implications in the literature, Computer Simulated Experiment (CSE) seems to be a satisfactory approach that can be used to promote students' science achievement, and it is important to test how successful it will be when compared to Hands on Laboratory (HOL) study. Purpose of Study: The main purpose of this study was to investigate the effectiveness of CSE over HOL study on the understanding of velocity and displacement concepts when both teaching methods were used as a supplement to regular classroom instruction. The second purpose was to identify whether logical thinking ability accounted for a significant portion of variation in achievement related to velocity and displacement concepts. Methods: In this study, the pretest/post-test control group design was used. Each treatment (CSE & HOL) was randomly assigned to the experiment group and the control group. Both groups were administered a pretest of Velocity and Displacement Concepts Achievement Test (VDCAT) and a Logical Thinking Ability Test as dependent variables. Then, both groups were post-tested with the same VDCAT. The sample of the present study consisted of 61 tenth grade students enrolled in two physics classes of the same teacher in a high school. Findings and Results: Post-test scores revealed that a significant difference was obtained between the mean scores attained by the CSE group and hands-on group with respect to physics achievement. The CSE group scored significantly higher than the hands-on group with respect to achievement in physics related to velocity and displacement concepts. On the other hand, logical thinking ability accounted for a significant portion of variance in physics achievement. Conclusions and Recommendations: Computer-simulated laboratory experiments, together with classroom instruction, appear to be a practical strategy in implementing a physics program. They can be organized such that the application of physics concepts is stressed. This approach will improve understanding of physics subject matter. Well-designed computer simulations can be used for teaching some concepts without extra effort and time from the teacher to prepare materials.Publication Evaluation of visual-motor integration functions in children between 6-15 years of age(Türkiye Sinir ve Ruh Sağlığı Derneği, 2010) Tekok Kılıç, Ayda; Elmastaş Dikeç, Banu; Can, Handan; Uludağ Üniversitesi/Fen-Edebiyat Fakültesi/Psikoloji Bölümü.; AAH-8501-2021; 36165087700; 55371079500Objective: Visual-motor integration skills are considered an essential domain of clinical and psycho-educational assessment. The goal of the present investigation is to provide the Turkish norms for the Beery-Buktenica Developmental Visual-Motor Integration Test (VMI-4th) for children and adolescents between the ages of 6-15 years as part of a comprehensive neuropsychological test battery. Method: A total of 1887 children from elementary and high schools in the city of Bursa were recruited for this study. From this sample 44 children were re-tested 3-4 weeks following the first administration for test-retest reliability. Results: Findings showed clear developmental trajectories in visual-motor integration skills. Significant performance increments were observed in six month intervals for ages 6 and 7. Starting from age 8, norms were established for each age group separately. Girls and boys performed similarly on the VMI-4. Test- retest correlation was modest but within an acceptable range. Conclusion: The age-based norms established for the VMI-4 in this study can be used to assess children between the ages of 6-15 years as part of a clinical neuropsychological and a psycho-educational assessment. The mean VMI scores presented in this study represent performance of children in middle and middle-upper socio-economic status and may not represent the normal performance range of children from lower SES.Publication Genetic algorithm with local search for the unrelated parallel machine scheduling problem with sequence-dependent set-up times(Taylor & Francis, 2014) Yılmaz, Duygu Eroğlu; Özmutlu, Hüseyin Cenk; Özmutlu, Seda; Uludağ Üniversitesi/Mühendislik Fakültesi/Endüstri Mühendisliği Bölümü.; AAH-1079-2021; AAH-4480-2021; ABH-5209-2020; 56120864000; 6603061328; 6603660605In this paper, a genetic algorithm (GA) with local search is proposed for the unrelated parallel machine scheduling problem with the objective of minimising the maximum completion time (makespan). We propose a simple chromosome structure consisting of random key numbers in a hybrid genetic-local search algorithm. Random key numbers are frequently used in GAs but create additional difficulties when hybrid factors are implemented in a local search. The best chromosome of each generation is improved using a local search during the algorithm, but the better job sequence (which might appear during the local search operation) must be adapted to the chromosome that will be used in each successive generation. Determining the genes (and the data in the genes) that would be exchanged is the challenge of using random numbers. We have developed an algorithm that satisfies the adaptation of local search results into the GAs with a minimum relocation operation of the genes' random key numbers - this is the main contribution of the paper. A new hybrid approach is tested on a set of problems taken from the literature, and the computational results validate the effectiveness of the proposed algorithm.Publication Growth and stomatal behaviour of two strawberry cultivars under long-term salinity stress(TÜBİTAK, 2007) Turhan, Ece; Eriş, Atilla; Uludağ Üniversitesi/Ziraat Fakültesi/Bitki Koruma Bölümü.; 0000-0003-0991-3802; AAH-3180-2020Sodium chloride (NaCl) treatments were conducted on strawberry plants (Fragaria x ananassa cvs. Camarosa and Chandler) grown under greenhouse conditions. Modified Hoagland solution (one-third strength) containing 0 (control), 8.5, 17.0 and 34.0 mM NaCl was applied to the plants for 6 months. High NaCI concentrations caused serious reductions in growth parameters such as fresh weight (FW) of leaves, stems and roots, leaf area and the number of leaves. Addition of salt to the growth medium caused a reduction in stomatal conductance (Gs) and transpiration rate (E) of Camarosa. Saline water up to 34 mM NaCI did not have any influence on Gs of Chandler. In addition, 34 mM NaCl treatment caused a marked increase in Gs and E of Chandler. On the other hand, leaf temperature (Ti) increased with salt treatments in both cultivars. We suggest that the reductions in stomatal conductance and transpiration rate represent adaptive mechanisms to cope with excessive salt in Camarosa. As it can relatively maintain its stomatal conductance and transpiration rate, Chandler also tolerates the salt injury at low salt concentrations. Considering the cultivars. Camarosa was characterised as more salt tolerant than Chandler under saline conditions.Publication Helicobacter pylori izolatlarının antibiyotik direnç oranları ve klaritromisine dirençli suşların saptanmasında E-test ve floresan in situ hibridizasyon yöntemlerinin karşılaştırılması(Ankara Mikrobiyoloji Derneği, 2009-04) Özbey, Saliha Bakir; Özakın, Cüneyt; Keskin, Murat; UIudaǧ Üniversitesi/Tıp Fakültesi/Klinik Bakteriyoloji ve Enfeksiyon Hastalıkları Anabilim Dalı.; Uludaǧ Üniversitesi/Tıp Fakültesi/Mikrobiyoloji Anabilim Dalı.; Uludaǧ Üniversitesi/Tıp Fakültesi/Gastroenteroloji Anabilim Dalı.; 0000-0001-5428-3630; 0000-0003-4526-4352; AAG-8392-2021; 24480281800; 57200678942; 23050640000Helicobacter pylori which is one of the commonly seen chronic bacterial infections in the world, has been demonstrated to have a relationship with chronic gastritis, peptic ulcer disease and gastric cancer. Current management of H.pylori infection involves the use of a proton pump inhibitor (PPI) and any two of amoxicillin, clarithromycin and metronidazole in combination. Antibiotic resistance which is in an increasing trend in H.pylori since the recent years, is the main cause of treatment failure. This study was conducted to determine the susceptibility of 31 H.pylori strains to several antibiotics by using E-test method (AB Biodisk, Sweden) and also to detect clarithromycin resistance by fluorescent in situ hybridization (FISH; SedFAST (R), Hungary). The strains were isolated from the gastric biopsy specimens of patients who were admitted to Uludag University Hospital, Bursa, Turkey with dyspeptic complaints. Clarithromycin, amoxycillin, metronidazole, tetracycline and ciprofloxacin resistance rates were as 41.9%, 3.2%, 41.9%, 3.2% and 45.2%, respectively. Resistance to single antibiotic was detected in 32.2% of the isolates whereas multiresistance was seen in 45.2%. For the hybridization process one probe specific for 16S rRNA and labeled with a fluorescein dye and the other probe specific for the mutations in 23S rRNA and labeled with Cy3 stain were used. Green signalling denoted presence of H.pylori in the specimen and red signalling was associated with clarithromycin resistance. All of the isolates yielded green signalling and the 13 isolates found to be resistant to clarithromycin by E-test, gave red signalling. No difference was detected between the two methods in terms of clarithromycin resistance determination. This was a preliminary study reporting the H.pylori resistance rates in our region, however, further larger scale studies are required for obtaining countrywide data.Publication Hemostatic effect of a chitosan linear polymer (Celox (R)) in a severe femoral artery bleeding rat model under hypothermia or warfarin therapy(Ulusal Travma ve Acil Cerrahi Derneği, 2011) Köksal, Özlem; Özdemir, Fatma; Çametöz, Betül; İşbil Büyükcoşkun, Naciye; Sığırlı, Deniz; Uludağ Üniversitesi/Tıp Fakültesi/Acil Tıp Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Fizyoloji Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/İstatistik Anabilim Dalı.; 0000-0003-2271-5659; AAK-8332-2020; AAH-1692-2021; AAA-7472-2021; 23389880200; 7006765911; 57215331517; 55665951400; 24482063400In this study, the hemostatic efficacy of Celox (R) in rats under hypothermia or warfarin treatment was investigated. A total of forty-eight Sprague-Dawley female rats weighing 200-350 g were used in the study. Six experimental study groups were designed, as follows: Group 1: Normothermia + compression; Group 2: normothermia + Celox (R); Group 3: hypothermia + compression; Group 4: hypothermia + Celox (R); Group 5: normothermia + warfarin + compression; and Group 6: normothermia + warfarin + Celox (R). Celox (R) provided effective hemorrhage control in all three tested groups. There was a statistically significant difference between compression and Celox (R) implementation in all groups in terms of hemostasis (p-values for the normothermia, hypothermia and warfarin groups were p < 0.05, p < 0.01 and p < 0.01, respectively). Furthermore, the compression numbers were significantly lower in all of the groups that received Celox (R) than in those in which compression alone was applied (p-values for the normothermia, hypothermia and warfarin groups were p < 0.01, p < 0.01 and p < 0.001, respectively). Celox (R) provides effective hemorrhage control under conditions of normothermia, hypothermia and use of the oral anticoagulant agent warfarin.Publication Histological and histochemical investigations on the structural aspects of the testis of adult brown bear (Ursus archtos arctos)(TÜBİTAK, 1997) Özfiliz, Nesrin; Uludaǧ Üniversitesi/Veterinerlik Fakültesi.; AAH-2756-2021; 6506533788The study carried out on mature Brown Bears brought to the Wild Life Research Center of Uludag University, Faculty of Veterinary Medicine, for rehabilitation. The bears were castrated before sending them to a wild life sanctuary for preventing their over breeding. Structural differences in the testes of bears in sexually active and inactive state were shown by using histological, histochemical and histometrical methods. Testes were cut longitudinally into two pieces and the lengths were measured. The tissue pieces taken from four different parts of one piece, fixated in buffered formalin to demonstrate the parenchyma and excretory ducts. The 5-7 micron sections cut from paraffin blocks, stained with Crosmon's Triple stain for morfological features, Gomori's silver stain and Pinkus' orcein-giemsa stain for connective tissue fibers, Me Manus' periodic-acide schiff technique for glycosaminoglycans. The 10-15 micron cryostat sections were stained with Oil-red O stain method for lipids. The average diameters of seminiferous tubules were measured with the method of Gill and Leighton. The average lengths of testes in active state were found longer than in inactive state. In the active state tunica albuginea of testes was thicker than in the inactive state. In the sexually active state it was observed that the walls of tubuli seminiferi contorti were made up of 2-4 lines of cells while they were contracted and the wall was made up of 1-2 cell lines in the inactive state. The average diameters and thickness of epithelium lining ductuli efferentes, ductus epididimidis and ductus deferens were increased in the active state.Publication Histological and histochemical structure of the scrotal skin of adult brown bears (Ursus arctos arctos)(TÜBİTAK, 1997) Özfiliz, Nesrin; Özer, Aytekin; Uludaǧ Üniversitesi/Veterinerlik Fakültesi.; AAH-2756-2021; 6602532634; 7005139374The study carried out on the scrotal skin of Brown bears brought to the Wild life Research Center of Uludag University, Faculty of Veterinary Medicine. Macroscopically, scrotal skin was considerably thick and its surface was wrinkled, dark coloured and sparsely haired. On the light microscope, it was observed that the scrotal skin was composed of two main layers, epidermis and dermis. On the epidermal-dermal junction, a basement membrane rich in reticular fibers was seen. The smooth muscle bundles in stratum papillare were smaller than of stratum reticulare. The hair follicles sparsely noticed in stratum reticulare didn't have any arrectores muscles. The primary and secondary follicles couldn't be distinguished. Sebaceous glands were noticed near the hair follides in stratunt reticulare and the deeper parts of stratum papillare. Generally, scrotal skin was rich in sweat glands located in the same level with sebaceous glands or under the hair follicle bulbs. Sweat glands were lined by simple squamous or cuboidal epithelial cells depending on the stage of secrotoric activity.
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