Person: YAVAŞCAOĞLU, BELGİN
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YAVAŞCAOĞLU
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BELGİN
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Publication Preemptive analgesic effects of intravenous paracetamol in total abdominal hysterectomy(Kare Publ, 2009-04-01) Arıcı, Semih; Gurbet, Alp; Türker, Gürkan; Yavaşcaoğlu, Belgin; Şahin, Şükran; Arıcı, Semih; GURBET, ALP; TÜRKER, YUNUS GÜRKAN; YAVAŞCAOĞLU, BELGİN; Şahin, Şükran; Tıp Fakültesi; Anestezi ve Reanimasyon Ana Bilim Dalı; 0000-0002-6503-8232; 0000-0002-3019-581X; 0000-0003-4820-2288; A-7994-2018; AAI-7914-2021; JZE-5924-2024; AAI-6642-2021; AAG-9356-2021Objectives: Paracetamol is primarily thought to be a cyclooxygenase inhibitor acting through the central nervous system. Indirect effects of paracetamol are through the serotoninergic system as a non-opioid analgesic. In this study, total abdominal hysterectomy patients were given intravenous (iv) paracetamol 1 g preoperatively or intraoperatively to assess its postoperative analgesic effects.Methods: 90 patients undergoing total abdominal hysterectomy were enrolled into the study. Patients were randomized into three groups: in Group I, iv paracetamol 1 g was given 30 minutes prior to induction. In Group II, iv paracetamol 1 g was given prior to skin closure. Group III served as the control group and received saline as placebo. Postoperatively, all patients received morphine via patient-controlled analgesia pump. Postoperatively, rest and activity pain scores, sedation scores, hemodynamic parameters, postoperative morphine consumption, side effects, patient satisfaction, and total hospital stay were recorded.Results: In the control group, at rest and movement pain scores and total morphine consumption via patient-controlled analgesia were higher than in Groups I and II. When Groups I and II were compared, total morphine consumption was much greater in Group II. Intravenous paracetamol intraoperatively and postoperatively did not result in any hemodynamic effects.Conclusion: In total abdominal hysterectomy, preemptive iv paracetamol 1 g provided good quality postoperative analgesia, with decreased consumption of morphine and minimal side effects.Publication Comparison of esmolol to nitroglycerine in controlling hypotension during nasal surgery(Aves, 2012-08-01) Güney, Ayla; Kaya, Fatma Nur; Yavaşcaoğlu, Belgin; Gurbet, Alp; Selmi, Nazan Has; Kaya, Şener; Kutlay, Oya; Güney, Ayla; KAYA, FATMA NUR; GURBET, ALP; YAVAŞCAOĞLU, BELGİN; Selmi, Nazan Has; Kaya, Şener; Kutlay, Oya; Tıp Fakültesi; Anesteziyoloji ve Reanimasyon Ana Bilim Dalı; 0000-0003-4820-2288; 0000-0002-6503-8232; EXO-4828-2022; HPG-2667-2023; AAG-9356-2021; A-7994-2018; FVA-4074-2022; CYU-8986-2022; FFP-7118-2022Objective: The aim of this study was to compare esmolol to nitroglycerine in terms of effectiveness in controlling hypotension during nasal surgery.Materials and Methods: After approval by our institutional Ethics Committee, 40 patients were recruited and randomized into two drug groups: esmolol (Group E) and nitroglycerine (Group N). In group E, a bolus dose of 500 mu g/kg esmolol was administered over 30 sec followed by continuous administration at a dose of 25-300 mu g/kg/min to maintain systolic arterial pressure at 80 mmHg. In group N, nitroglycerine was administered at a dose of 0.5-2 mu g/kg/min.Results: During the hypotensive period, systolic arterial pressure, diastolic arterial pressure, mean arterial pressure, and heart rate were decreased 24%, 33%, 27% and 35%, respectively, in group E (p<0.001, p<0.001, p<0.001, p<0.001) and were decreased 30%, 33%, 34% and 23%, respectively, in group N (p<0.001, p<0.001, p<0.001, p<0.001). The decrease in heart rate was higher in group E during the hypotensive period (p=0.048). During the recovery period, diastolic arterial pressure and heart rate were decreased 9% and 18%, respectively, in group E (p=0.044, p<0.001). Systolic arterial pressure, diastolic arterial pressure, and mean arterial pressure were decreased 7%, 3% and 7%, respectively, in group N (p=0.049, p=0.451, p=0.045).Conclusion: Esmolol provides hemodynamic stability and good surgical field visibility and should be considered as an alternative to nitroglycerine.Publication The effect of local anaesthetic on post-operative pain with wound instillation via a catheter for paediatric orthopaedic extremity surgery(British Editorial Soc Bone Joint Surgery, 2011-06-01) Bulut, T.; Yılmazlar, Aysun; Yavaşçaoğlu, Belgin; YAVAŞCAOĞLU, BELGİN; Sarısözen, Bartu; SARISÖZEN, MEHMET BARTU; Tıp Fakültesi; Anestezi ve Reanimasyon Ana Bilim Dalı; 0000-0003-4820-2288; 0000-0003-4071-8052; AAG-9356-2021; AAI-7914-2021; ABI-7283-2020Purpose We aimed to investigate the effects on postoperative pain of local anaesthetic administration via a catheter placed into the operation site in patients who were undergoing upper and lower extremity paediatric orthopaedic surgery.Methods In this randomised, double-blind and placebo study, 40 ASA I-II patients aged between 1 and 12 years were randomly allocated into two groups: study group (Group S: 0.2 ml/kg, 0.5% bupivacaine, n = 20) and control group (Group C: 0.2 ml/kg, serum physiologic, n = 20). Before the fascia was closed by the surgical team, the solution previously prepared by the chief nurse was injected into the subfascial soft tissue with the syringe as the "injected dose'' of serum physiologic or bupivacaine. After the closure, 0.2 ml/kg (1 mg/kg) bupivacaine or saline was instillated as the "first instillated dose'' into the surgical area via the catheter. Pain scores were recorded at 0, 1, 2, 4, 8, 12, 24 and 48 h post-operatively. Patients were administered 0.75 mg/kg meperidine intramuscularly post-operatively to equalise the pain scores.Results No statistically significant difference was found between Group S and Group C in terms of demographic and other data and pain scores in the post-anaesthesia care unit, while a statistically significant decrease was found at 2, 4, 8, 12, 24 and 48 h in Group S and at 1, 2 and 4 h in Group C based on pain scores in the post-anaesthesia care unit (P < 0.05). A statistically significant decreasing pain score was found at 4, 8, 12, 24 and 48 h in Group S (P < 0.05).Conclusion The local anaesthetic administered via a catheter implanted in the surgical field may provide long-term and efficient post-operative analgesia.Publication Mobbing exposure of anaesthesiology residents in Turkey(Aves, 2016-08-01) Aykut, Gülnihal; Efe, Esra Mercanoğlu; Bayraktar, Selcan; Şentürk, Sinem; Başeğmez, İrem; Özkumit, Özlem; Kabak, Elmas; Yavascaoğlu, Belgin; Bilgin, Hülya; Aykut, Gülnihal; Efe, Esra Mercanoğlu; Bayraktar, Selcan; Şentürk, Sinem; Başeğmez, İrem; Özkumit, Özlem; Kabak, Elmas; YAVAŞCAOĞLU, BELGİN; BİLGİN, HÜLYA; Tıp Fakültesi; Anesteziyoloji ve Reanimasyon Ana Bilim Dalı; 0000-0001-6639-5533; HRC-4365-2023; A-7338-2016; ENT-8289-2022; CMY-6041-2022; EKO-8143-2022; FYQ-5276-2022; CDL-1118-2022; FPM-3480-2022; FFB-8990-2022Objective: In recent years, psychological problems that are caused by working conditions, like burn out syndrome, are more commonly observed. In our study, we aimed to evaluate mobbing exposure, factors causing mobbing and precautions for mobbing in residency students who are educated in anaesthesiology and reanimation clinics in Turkey.Methods: After obtaining consent from the ethics committee, we sent our questionnaires to the secretariats of the departments by postal mail. Completed questionnaires were collected in our department's secretariat blindly and randomly mixed. One hundred and one participants were returned the questionnaires. Data was statistically analysed in SPSS 21.0 software programme.Results: During residency programme, sated to have experienced mobbing one or more time. Interestingly, 5.9% participants complained of physical mobbing. Mobbing exposure was more common in females. The most serious new onset psychosomatic symptoms stated during residency were committing suicide (2%), addiction (16%), severe depression (18%), panic attack (8%), more accidents (7%) and tendency of violence (15%). In mobbing group there was statistically significant dissatisfaction rate.Conclusion: In professions where mobbing is common, incidences of psychiatric diseases and suicide attempts are high are increased. Who are under risk for experiencing mobbing should be noticed carefully to ensure good judgement and problems should be inspected objectively in a detailed manner. Anesthesiology societies and other medical professional societies should establish mobbing committees. Thus, mobbing problems can be resolved and healthy career oppurtunities can be presented to residents.Publication Conscious sedation for endoscopic retrograde cholangiopancreatography: Dexmedetomidine versus midazolam(Aves, 2011-04-01) Kılıç, Neslihan; Şahin, Şükran; Aksu, Hale; Yavaşcaoğlu, Belgin; Gurbet, Alp; Türker, Gürkan; Kadıoğlu, Aslı Güler; Kılıç, Neslihan; Şahin, Şükran; Aksu, Hale; YAVAŞCAOĞLU, BELGİN; GURBET, ALP; TÜRKER, YUNUS GÜRKAN; Kadıoğlu, Aslı Güler; Tıp Fakültesi; Anesteziyoloji ve Reanimasyon Ana Bilim Dalı; 0000-0002-4887-1337; 0000-0003-4820-2288; 0000-0002-6503-8232; 0000-0002-3019-581X; A-7994-2018; AAG-9356-2021; AAI-7914-2021; AAI-6642-2021; FDK-6768-2022; DPH-3881-2022; AAO-7943-2020; ILV-9196-2023Objective: Midazolam and dexmedetomidine, which are used for sedation during endoscopic retrograde cholangiopancreatography, were compared to evaluate the differences in efficacy, hemodynamics, and side effects.Materials and Methods: Fifty patients aged between 18 and 80 were randomly assigned to two groups according to American Society of Anesthesiologists (ASA) classification: Group M received midazolam with an initial bolus infusion of 0.04 mg/kg intravenously (i.v.), followed by additional doses of 0.5 mg i.v. midazolam, titrated to achieve a Ramsay sedation scale score of 3-4. Group D received dexmedetomidine with an initial bolus infusion of 1 mcg/kg/hr i.v. over 10 minutes, followed by a continuous infusion of 0.2-0.7 mcg/kg/hr, titrated to achieve an RSS of 3-4. A Mini Mental Status Examination (MMSE) was performed prior to sedation and in the recovery room once the Modified Aldrete Score (MAS) reached 9-10. Patient heart rates, arterial pressure and pain were evaluated.Results: Patients in Group D had lower heart rates at 20, 25, 30, 35 and 40 minutes following the initiation of sedation (p<0.05). There was no statistical difference in arterial pressure, RSS, MMSE or respiratory rate between the two groups. Coughing, nausea and vomiting occurred in 3 patients in Group M (12%), whereas no patient in Group D experienced these symptoms. The procedure elicited a gag response in 7 patients in Group M (28%) and in 4 patients in Group D (16%), with no significant difference between groups (p>0.05). When patient and surgeon satisfaction was compared between the two groups, Group D showed higher surgeon satisfaction scores (p<0.05).Conclusion: The use of dexmedetomidine for conscious sedation during short, invasive procedures, such as endoscopic retrograde cholangiopancreatography, could be a superior alternative to the use of midazolam.Publication General anesthesia for urgent caesarean section in a patient with untreated takayasu's arteritis(Int Scientific Information, Inc, 2008-01-01) Girgin, Nermin Kelebek; KELEBEK GİRGİN, NERMİN; Yavasçaoğlu, Belgin; YAVAŞCAOĞLU, BELGİN; Tıp Fakültesi; Anestezi ve Reanimasyon Ana Bilim Dalı; 0000-0003-4820-2288; AAG-9356-2021; AAH-7250-2019; AAI-7914-2021Background: Takayasu's arteritis (TA) is a rare form of nonspesific obliterative panarteritis, and resulting in multiple stenosis and occlusion of major arteries. Progression of the disease may be marked by aneurysmal dilatation of the affected arteries and may lead to fatal outcome, usually from cerebral ischemia or heart failure.In this case report, we describe a successful episode of anesthesia management with monitoring only mean arterial pressure (MAP) in a parturient affected with untreated TA during an urgent Caesarean section (C/S) under general anesthesia (GA).Case Report: A 25-yr-old woman with a history of TA, was scheduled for emergency C/S under GA for acute fetal distress without doing any laboratory tests or special procedures for TA. The MAP was measured as 153 mmHg in the operating room. Because of our technical insufficiency, we could not perform any cerebral monitoring. We started intravenous nitroglycerine infusion, and titrated during the intraoperative period in accordance to the MAP values. Peroperative and postoperative periods were uneventful, and she was discharged 5 days post partum.Conclusions: The case presented in this report suggested that, if the blood pressure of a patient with TA before and during the pregnancy is unknown, MAP could be used as a guide in order to protect the brain during general anesthesia, if there is no possibility of monitoring cerebral hemodynamics.