Person: YEŞİLDEMİR, ÖZGE
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YEŞİLDEMİR
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ÖZGE
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Publication Comparison of melamine exposure by feeding practices in babies aged 0-6 months(Elsevier, 2023-01-13) Yeşildemir, Özge; Akdevelioğlu, Yasemin; Köse, Selinay Başak Erdemli; Çakır, Deniz Arca; Yirun, Anıl; Özyurt, Aylin Balcı; Sabuncuoğlu, Suna; Çamurdan, Aysu Duyan; Çakır, Bahar Çuhacı; Erkekoğlu, Pınar; YEŞİLDEMİR, ÖZGE; Bursa Uludağ Üniversitesi/Sağlık Bilimleri Fakültesi/Beslenme ve Diyetetik Bölümü; AAG-7353-2021This study was conducted to estimate the daily dietary intakes of melamine for human milk-fed (HMF) babies and mixed-fed (MF) babies. It was carried out in 70 mother-baby pairs (40 babies in the HMF group and 30 babies in the MF group). Human milk, formula milk, and baby urine samples were collected to assess the dietary exposure of babies. Melamine concentrations were analyzed by using a competitive enzyme-linked immuno-sorbent assay. Melamine was determined in 82.5 % of the human milk samples in the HMF group (median: 0.75 mu g/L) while it was present in 96.7 % of human milk samples (median: 1.25 mu g/L) and 96.7 % in formula milk samples (median: 0.95 mu g/kg) in the MF group. The mean urinary melamine concentration of HMF babies (1.20 +/- 0.21 mu g/L) was not significantly different than MF babies (1.35 +/- 0.49 mu g/L). Melamine exposure was calculated as 0.12 mu g/kg bw/day and 0.24 mu g/kg bw/day in HMF and MF babies, respectively. Melamine exposure in both groups was below the tolerable daily intake. There were no significant associations between melamine exposure and various features of babies and mothers. As a result, it can be suggested that Turkish babies (aged 0-6 months) are not at risk for high melamine exposure through the diet.Publication Estimated exposure to bisphenol a in breastfed and breastfed plus formula-fed infants in turkey: A comparison study(Taylor, 2022-12-24) Yeşildemir, Özge; Akdevelioglu, Yasemin; Duyan Camurdan, Aysu; Cuhaci Cakir, Bahar; Erdemli Kose, Selinay Basak; Arca Cakir, Deniz; Yirun, Anil; Balci Ozyurt, Aylin; Sabuncuoglu, Suna; Erkekoglu, Pinar; YEŞİLDEMİR, ÖZGE; Bursa Uludağ Üniversitesi/Sağlık Bilimleri Fakültesi/Beslenme ve Diyetetik Bölümü; 0000-0003-2680-7147; AAG-7353-2021This study aimed to estimate and compare dietary exposure to bisphenol A (BPA) in exclusively breastfed (EBF) and breastfed plus formula-fed (BF + FF) infants. A total of 70 mothers and their 0-6 month-old infants (40 in the EBF group and 30 in BF + FF group) were included in the study. After the questionnaire form was applied to the mothers, maternal breast milk, infant formula, and infant urine were collected from mother-infant dyads. Total BPA levels in breast milk, infant formula, and infant urine samples were analyzed by the high-pressure liquid chromatography (HPLC). While BPA was detected in 92.5% of the breast milk samples in the EBF group (mean +/- SD = 0.59 +/- 0.29 ng/mL), BPA was detected in all of the breast milk samples in the BF + FF group (mean +/- SD= 0.72 +/- 0.37 ng/mL) (p < 0.05). Similarly, 100% of the infant formula samples in the BF + FF group had detectable levels of BPA (mean +/- SD = 7.54 +/- 1.77 ng/g formula). The mean urinary BPA levels in the EBF infants (4.33 +/- 1.89 mu g/g creatinine) were not statistically different from the BF + FF infants (5.81 +/- 0.11 mu g/g creatinine) (p > 0.05). The average daily BPA intake in EBF infants (0.18 +/- 0.13 mu g/kg body weight (bw)/day) was found to be significantly higher than in BF + FF infants (0.12 +/- 0.09 mu g/kg bw/day) (p < 0.05). The estimated dietary intakes of BPA for infants in both groups were below the temporary tolerable daily intake (t-TDI) (4 mu g/kg bw/day). Consequently, BPA intake of EBF and BF + FF infants were within safe daily limits during the first six months of life.Publication Gender-affirming nutrition: An overview of eating disorders in the transgender population(Springernature, 2023-10-21) Akbulut, Gamze; Yeşildemir, Özge; YEŞİLDEMİR, ÖZGE; Bursa Uludağ Üniversitesi/Sağlık Bilimleri Fakültesi.Purpose of ReviewTransgender individuals are vulnerable to many nutrition-related conditions, especially eating disorders due to gender dysphoria. This review aims to summarize the current literature on eating disorders in transgender individuals. The issues that should be considered in nutrition care for the transgender population are discussed regarding public health.Recent FindingsTransgender individuals can exhibit disordered eating behaviors to overcome the stress they experience due to stigma, discrimination, social exclusion, and abuse. Recent studies showed that disordered eating and clinical eating disorders are more prevalent among transgender than cisgender people. It is very important for a multidisciplinary team working in the clinic to understand the epidemiology, etiology, diagnostic criteria, and treatment of eating disorders in the transgender population. However, multidisciplinary nutritional care is limited due to the lack of transgender-specific nutrition guidelines. It is safe to say that adhering to a generally healthy nutritional pattern and using standardized nutrition guidelines. We recommend that health professionals working with patients/clients with eating disorders receive continuing education in transgender health, be empowering and inclusive, address patients/clients with their gender identity nouns and pronouns, and develop nutritional treatment plans that are not gender-specific.SummaryEating disorders are a significant public health problem in the transgender population. Therefore, clinical screening and early intervention are necessary to identify and treat eating disorders in transgender people. Eating disorders in the transgender population should be monitored routinely, and gender-affirming care should be provided as well as treatment of eating disorders.Publication The roles of dietary lipids and lipidomics in gut-brain axis in type 2 diabetes mellitus(Bmc, 2023-04-02) Agagündüz, Duygu; İcer, Mehmet Arif; Koçak, Tevfik; Koçyiğit, Emine; Capasso, Raffaele; Yeşildemir, Özge; YEŞİLDEMİR, ÖZGEType 2 diabetes mellitus (T2DM), one of the main types of Noncommunicable diseases (NCDs), is a systemic inflammatory disease characterized by dysfunctional pancreatic beta-cells and/or peripheral insulin resistance, resulting in impaired glucose and lipid metabolism. Genetic, metabolic, multiple lifestyle, and sociodemographic factors are known as related to high T2DM risk. Dietary lipids and lipid metabolism are significant metabolic modulators in T2DM and T2DM-related complications. Besides, accumulated evidence suggests that altered gut microbiota which plays an important role in the metabolic health of the host contributes significantly to T2DM involving impaired or improved glucose and lipid metabolism. At this point, dietary lipids may affect host physiology and health via interaction with the gut microbiota. Besides, increasing evidence in the literature suggests that lipidomics as novel parameters detected with holistic analytical techniques have important roles in the pathogenesis and progression of T2DM, through various mechanisms of action including gut-brain axis modulation. A better understanding of the roles of some nutrients and lipidomics in T2DM through gut microbiota interactions will help develop new strategies for the prevention and treatment of T2DM. However, this issue has not yet been entirely discussed in the literature. The present review provides up-to-date knowledge on the roles of dietary lipids and lipidomics in gut-brain axis in T2DM and some nutritional strategies in T2DM considering lipids- lipidomics and gut microbiota interactions are given.