Person: YÜCEL, AHMET ALİ
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Publication Efficacy of dexamethasone implants in uveitic macular edema in cases with behcet disease(Karger, 2019-01-01) Yalçınbayır, Özgür; Çalışkan, Enver; Gündüz, Gamze Uçan; Gelişken, Öner; Kaderli, Berkant; Yücel, Ahmet Ali; YALÇINBAYIR, ÖZGÜR; Çalışkan, Enver; UÇAN GÜNDÜZ, GAMZE; YÜCEL, AHMET ALİ; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Göz Hastalıkları Anabilim Dalı; JAC-9459-2023; EQX-5743-2022; AAH-6661-2021; JYV-1141-2024Purpose: Investigation of the efficacy of intravitreal dexamethasone implants (0.7 mg) in patients with Behcet disease (BD) who had cystoid macular edema (CME) despite immunomodulatory treatment. Materials and Methods: Twenty-seven eyes of 20 patients who had intravitreal dexamethasone implant injections and follow-up for more than 6 months were included in this study. Best corrected visual acuities (BCVA), intraocular pressures (IOP), and central macular thicknesses (CMT) were recorded. Systemic immunomodulatory treatment was noted. Injection-related complications and the need for recurrent injections were recorded. Results: Statistically significant anatomical and functional success was achieved with a single injection. BCVA increased from 0.85 +/- 0.72 to 0.45 +/- 0.52 logMAR, while the mean CMT decreased from 406 +/- 190 to 243 +/- 101 mu m at the sixth month. The peak of visual acuity gain was reached within the first 2 months and a substantial proportion of the patients gained 3 or more lines. There was no complication other than transient IOP elevation in 4 eyes and cataract surgery in 2 eyes. Conclusion: Adjuvant intravitreal dexamethasone implant injections offer promising results in cases of BD with CME. It is effective in preserving the macular anatomy and vision particularly in transition to biological agents.Publication Evaluation of choroidal thickness in children with type 1 diabetes: The role of optical coherence tomography in diabetic retinopathy screening(Japanese Soc Pediatric Endocrinology, 2021-01-01) Ermerak, Basak Can; Yalcinbayir, Ozgur; YALÇINBAYIR, ÖZGÜR; Eren, Erdal; EREN, ERDAL; Erseven, Cansu; Sobu, Elif; Yucel, Ahmet Ali; YÜCEL, AHMET ALİ; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Oftalmoloji Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Endokrinoloji Anabilim Dalı.; 0000-0002-7311-5277; 0000-0002-1684-1053; JAC-9459-2023; AAH-6226-2021; IYJ-9408-2023; GSN-9730-2022; AAH-6625-2021The present study aimed to evaluate choroidal changes and alternations within the structure of the retina prior to visible morphologic signs of diabetic retinopathy (DR) in pediatric type 1 diabetes (T1D) cases. Two hundred and six eyes of 103 pediatric patients with T1D without DR and 88 eyes of 44 healthy controls were enrolled. They underwent a comprehensive ophthalmic examination and optical coherence tomography evaluation. Choroidal thickness (ChT) measurements were performed manually on macular and peripapillary regions. There was no significant difference between the two groups in terms of age, intraocular pressure, and axial length (p > 0.05). ChT measurements of subfoveal, nasal, and temporal macula were slightly thinner in the diabetic group, and no statistical significance was found (p = 0.835, p = 0.305, and p = 0.054, respectively). Peripapillary ChT of eight sectors were also thinner in T1D; however, superonasal, nasal, inferonasal, and inferior sector values were significantly different (p = 0.010, p = 0.020, p = 0.019, and p = 0.018, respectively). In conclusion; this study demonstrated evidence of peripapillary choroidal thinning in pediatric diabetic patients without visible signs of retinopathy.Publication Myocardial performance is impaired in patients with branch retinal vein occlusion(Sage Publications, 2015-02-01) Kaderli, Berkant; Kaderli, Aysel Aydın; Güllülü, Sümeyye; İnan, Ümit Ubeyt; Şentürk, Tunay; Aydınlar, Ali; Yücel, Ahmet Ali; Avcı, Remzi; Kaderli, Berkant; GÜLLÜLÜ, NAZMİYE SÜMEYYE; ŞENTÜRK, TUNAY; AYDINLAR, ALİ; YÜCEL, AHMET ALİ; Kaderli, Aysel Aydın; Uludağ Üniversitesi/Tıp Fakültesi/Göz Hastalıkları Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Kardiyoloji Anabilim Dalı.; AAI-6632-2021; C-1517-2017; FDM-9757-2022; CXL-7581-2022; EXG-3181-2022; JYV-1141-2024Objective To investigate whether the Tei index, which is an indicator of global myocardial function and an independent predictor of cardiac death, is increased in patients with branch retinal vein occlusion (BRVO).Methods The Tei index was used to evaluate myocardial performance, in addition to conventional echocardiographic evaluation of myocardial structural and functional changes, in patients with BRVO, patients with hypertension and healthy controls.Results Out of 36 patients with BRVO (18 female, 18 male; 17 hypertensive, 19 normotensive), 29 patients with hypertension (15 female, 14 male) and 28 healthy controls (15 female, 13 male), there were no significant between-group differences in age and sex. The mitral A wave was higher and mitral E/A ratio, mitral E wave and ejection time were lower, in patients with BRVO than in healthy controls. Mean Tei index was significantly higher in the BRVO group than in patients with hypertension or healthy controls. Compared with healthy controls, the Tei index was significantly higher in hypertensive and normotensive patients with BRVO.Conclusion Myocardial performance is decreased in patients with BRVO, independent of whether or not they have hypertension.Publication Evaluation of occupational closed globe eye(Derman Medical Publ, 2015-06-01) Budak, Berna Akova; Kıvanç, Sertaç Argün; KIVANÇ, SERTAÇ ARGUN; Başkaya, Kevser; Baykara, Mehmet; BAYKARA, MEHMET; Yücel, Ahmet Ali; YÜCEL, AHMET ALİ; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Göz Hastalıkları Anabilim Dalı.; 0000-0003-0995-5260; 0000-0002-5555-1649; ABE-3033-2020; AAH-6518-2021; ABI-7051-2020Aim: To evaluate closed glob injuries related to occupational accidents of patients who had official occupational accident records. Material and Method: The medical records of patients with ocular injuries who referred to Department of Ophthalmology or emergency of Uludag University, School of Medicine between January 2010 and December 2013 with official occupational accident report were retrospectively reviewed. The patients with closed globe injuries following trauma were included. Age, sex, the injured eye, the cause of the trauma, whether the precautions were taken or not by the patient, the damage due to trauma were recorded. Results: According to the official records, 108 patients referred to our clinic with closed globe injury related to occupational accident. One hundred twenty eyes of 108 patients (2 females, 106 males) were evaluated. The mean age of the patients was 33 +/- 8.6 years. The most frequent cause of injury was foreign bodies on the ocular surface followed by blunt trauma. The mean age of the patients injured with foreign bodies was found to be significantly lower than the patients injured with blunt objects (p=0.039). Thirteen patients reported that they had used preventive equipment. Discussion: It is of utmost importance that the awareness of the workers should be raised and they should be educated about the use of preventive equipment to prevent the occupational eye injuries. The education of particularly the younger patients about the occupational injuries when they begin to work may decrease the rate of occupational accident related eye injuries.Publication The clinical and demographic characteristics of pediatric behcet's patients(Galenos Yayıncılık, 2008-12-01) Sarıcaoğlu, Hayriye; Erdem, Hatice; Toker, Semra Çıkman; Başkan, Emel Bülbül; Yücel, Ali; Tunalı, Şükran; SARICAOĞLU, HAYRİYE; Erdem, Hatice; Toker, Semra Çıkman; BÜLBÜL BAŞKAN, EMEL; YÜCEL, AHMET ALİ; Tunalı, Şükran; Uludağ Üniversitesi/Tıp Fakültesi/Dermatoloji ve Zührevi Hastalıkları Anabilim Dalı.; 0000-0001-7992-0974; AAH-1388-2021; KEH-2402-2024; HIZ-7238-2022; DPU-8534-2022; JNO-6991-2023; GGH-7385-2022Aim: In this study, we aimed to compare the clinical and demographic features of pediatric Behcet's patients with those of adult age.Materials and Method: We examined the clinical and demographic features of the 18 and under 18-year-old children who were followed-up in the Behcet's Center of Uludaij University Medical Faculty between 1992 and 2007, retrospectively. The information of age, sex, presence of oral aphthous ulcers, genital ulcers, erythema nodosum, papulopustular eruption, pathergy test positivity, ocular, articular, neurological, gastrointestinal, renal involvements and HLA-B5 positivity were obtained from the medical charts of the patients.Results: There were 30 pediatric Behcet diagnosed according to the diagnostic criteria of International Study Group for Behcet's Disease. The mean age of the patients was 15.9. At the time of the diagnosis, most of the patients were aged between 17-18 (43.3%). There was only one patient under 10. Oral aphthae was observed in all, and genital ulceration or the scar of the ulcer was observed in 23 patients; 15 females, 8 males (76.6%). Ocular involvement was present in 18 patients; 8 females, 10 males (60%); erythema nodosum in 13 patients; 8 females, 5 males (43.3%), papulopustular eruption in 16 patients; 10 females, 6 males and pathergy test positivity in 12 patients; 7 females, 5 males (36.6%). Vascular symptoms were observed in 2 patients, arthralgia-arthritis in 15 patients and neurological involvement in 4 patients.Conclusion: In this study, it was concluded that ocular involvement was more frequent in Behget's patients aged between 0-18 than adult Behcet's patients, but mucocutaneous findings had similar frequency.Publication Optic disc vasculitis in behcet's disease(Assoc Research Vision Ophthalmology Inc, 2004-04-01) Suner, K; Sarıcaoğlu, Halim; Dilek, Kanmaz; Kaderli, Berkant; Yücel, Ahmet Ali; YÜCEL, AHMET ALİ; Bursa Uludağ Üniversitesi/Tıp Fakültesi.