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SONAT, FÜSUN

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2015 - 201922020 - 20231
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    Publication
    The effect of orally administrated β-glucan and dietary restriction on faecal microflora in rats
    (Kafkas Üniversitesi, 2015-01-01) Elal Muş, Tülay; Ak Sonat, Füsun; ELAL MUŞ, TÜLAY; SONAT, FÜSUN; Uludağ Üniversitesi/Veteriner Fakültesi/Gıda Hijyeni ve Teknolojisi Anabilim Dalı.; Uludağ Üniversitesi/Veteriner Fakültesi/Fizyoloji Anabilim Dalı.; 0000-0002-3943-0097; AAG-8396-2021; K-1637-2017; AAW-5282-2020
    In this study we aimed to evaluate the effect of orally administered beta-glucan and/or dietary restriction on Lactobacillus spp., coliforms, Enterobacteriaceae and enterococci counts in rat faeces. For this aim, rats were divided into three experimental groups: i) first group animals received normal diet for 6 months and administrated orally with beta-glucan (20 mg/kg for bodyweigth) over the last 14 day of experiment, ii) second group was dietary restricted animals for 6 months and receiving beta-glucan as those of first group animals, iii) last group was the control group rats receiving only ad libitum feed. Compared to control group, numeric increase was observed in the number of coliforms, Enterobacriaceae and lactobacillus counts in first group but this was not statistically important. The increase in coliforms and Enterobacteriaceae counts was nearly 2 log while this was 1 log for lactobacillus counts. Interestingly, dietary restriction + beta-glucan administration had no significant influence on the increase of defined bacterial groups. The results of the present study showed that orally administration of the beta-glucan, widely used as prebiotic, has the potential to modify faeces microbiota in rat model.
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    Publication
    Effect of dietary restriction on probiotic bacteria lactobacillus
    (Wiley, 2015-09-01) Muş, Tülay Elal; Sonat, Füsun Ak; Altınbaş, Burin; ELAL MUŞ, TÜLAY; SONAT, FÜSUN; Altınbaş, Burin; Uludağ Üniversitesi/Keles Meslek Yüksekokulu/Gıda Teknolojisi Programı.; Uludağ Üniversitesi/Veteriner Fakültesi/Fizyoloji Anabilim Dalı.; 0000-0002-3943-0097; AAG-8396-2021; AAW-5282-2020; K-1637-2017
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    Publication
    Effects of algae derived pure β-Glucan on in vitro rumen fermentation
    (Ankara Üniversitesi, 2023-01-01) Sucu, Ekin; Sonat, Füsun; SUCU, EKİN; SONAT, FÜSUN; Bursa Uludağ Üniversitesi/Ziraat Fakültesi/Zootekni Bölümü; Bursa Uludağ Üniversitesi/Veteriner Fakültesi/Fizyoloji Anabilim Dalı; 0000-0003-1470-2751; AAG-8331-2021; AAG-8396-2021
    The major purpose of this study was to determine how varying doses of algae derived pure r3-glucan affected in vitro gas generation, volatile fatty acid (VFA) concentrations, methane production, and protozoa populations. Different doses of r3-glucan [i.e., 0, 50, 100, 150, and 200 mg/kg feed (DM basis)] were applied to corn silage as experimental treatments. After 6-96 hours of incubation, the dose of 200 mg/kg of DM r3-glucan reduced total gas production compared to control (P<0.01). The concentration of total VFA decreased quadratically (P<0.01) as the amount of r3-glucan inclusion decreased (except for 200 mg/kg DM) when compared to the control group. The total VFA concentration was found to be the lowest (P<0.01) at 50, 100, and 150 mg/kg DM r3-glucan than the other doses. Propionate and butyrate concentrations increased linearly (P<0.01) in the r3-glucan supplemented groups, except for the 50 mg/kg DM dosage. When compared to the control group, all doses of r3-glucans lowered acetate and the acetate: propionate ratio linearly and quadratically (P<0.01). The addition of r3-glucans reduced the number of protozoa linearly (except at the lowest dose) and reduced the methane generation linearly and quadratically (P<0.01). The concentration of NH3-N did not differ (Linear, P=0.12; Quadratic, P=0.19) between treatments. The key findings were that r3-glucan acted as a rumen modulator, and levels of more than 50 mg/kg of feed DM functioned as a potential methane regulator in the rumen due to reduced acetate and acetate to propionate ratio.