Person: UZABACI, ENDER
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UZABACI
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ENDER
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Publication Her-2 positivity rate in dogs with mammary carcinoma: A systematic review and meta-analysis(Hellenic Veterinary Medical Soc, 2020-04-01) Uzabacı, Ender; UZABACI, ENDER; Özyiğit, Musa Özgür; ÖZYİĞİT, MUSA ÖZGÜR; Ercan, İlker; Arda, O.; Bursa Uludağ Üniversitesi/Veteriner Fakültesi/ Patoloji Anabilim Dalı.; Bursa Uludağ Üniversitesi/Veteriner Fakültesi/ Biyoistatistik Anabilim Dalı.; 0000-0002-9634-0055; 0000-0002-2382-290X; JPL-5273-2023; ABF-2367-2020; AAR-6478-2021Human epidermal growth factor receptor 2 (HER-2) plays an essential role in cell growth and survival. HER-2 overexpression occurs in 20-30% of human breast tumors and has prognostic value as it is associated with disease progression. HER-2 overexpression is also associated with tumor progression and metastasis in malignant mammary tumors of the canine. However, in the literature, different positivity classifications/scoring were used in the evaluation of HER-2 status, and there is no consensus in terms of scoring of HER-2 expression in canine mammary tumors. In this study, it was aimed to estimate the HER-2 positivity rate by evaluating the results of the study using different positivity classifications by meta-analysis. In this context, by using "HER-2 canine mammary tumor" keywords, Pubmed and Web of Science electronic databases were scanned until February 2019, and a total of 97 related studies were found. However, 20 of these studies were used for the analysis. Two different meta-analyses were performed to evaluate the HER-2 positivity status with "2+ and 3+" and "3+" scores. As a result, HER-2 positivity rates were determined at 25.87% and 25.99% for the studies using "2+/3+" scores and "3+" respectively for HER-2 positivity. Therefore, this result suggests that the rate of HER-2 positivity is similar between humans and dogs.Publication Characterization of commercially available propolis products in Turkey based on individual phenolic compounds(Taylor & Francis, 2021-06-14) Oruç, Hasan Hüseyin; Çaycı, Meltem; Sorucu, Ali; Uzabacı, Ender; Nyandwi, Ramadhan; ORUÇ, HASAN HÜSEYİN; Çaycı, Meltem; UZABACI, ENDER; Bursa Uludağ Üniversitesi/Veteriner Fakültesi/Farmakoloji ve Toksikoloji Anabilim Dalı.; Bursa Uludağ Üniversitesi/Sağlık Bilimleri Enstitüsü.; Bursa Uludağ Üniversitesi/Veteriner Fakültesi/Biyoistatistik Anabilim Dalı.; 0000-0002-5399-2395; 0000-0002-3401-9186; 0000-0002-9634-0055; 0000-0003-4371-425X; JMP-9327-2023; JPL-5273-2023; GBO-2873-2022The healing properties of propolis, such as antibacterial, antiviral, antifungal, anti-inflammatory, antitumoral, antioxidant, immunomodulatory, tissue regeneration, and anti-ulcer, are due to the high content of phenolic compounds (flavonoids and phenolic acids). Therefore, propolis can potentially be used for human consumption or even for medicinal purposes. This study aimed to analyze sixteen individual phenolic compounds that have beneficial effects, determine their concentrations in local and imported raw propolis and products consumed in Turkey, and evaluate the determined results for propolis quality. A total 91 propolis samples were collected from commercial raw propolis and propolis products, which were from different provinces of Turkey and different countries, sold and used in Turkey between 2015 and 2018. Sixteen phenolic compounds were analyzed by high-performance liquid chromatography with a diode array detector system. Regardless of their origin, the results indicated that the concentrations of individual phenolic compounds varied greatly within crude, ethanol-based, water-based, and propylene glycol propolis samples analysed. There were significant differences in some individual phenolic compounds between the local and imported samples (p < 0.05). The current results showed that qualitative and quantitative analysis of commercial propolis samples for useful phenolic compounds are important and may provide quality control of propolis products.Publication Attitudes of turkish veterinary students towards farm animal welfare(Univ Federation Animal Welfare, 2021-08-01) Çavuşoğlu, Enver; Uzabacı, Ender; ÇAVUŞOĞLU, ENVER; UZABACI, ENDER; Bursa Uludağ Üniversitesi/Veteriner Fakültesi/Zootekni Anabilim Dalı.; Bursa Uludağ Üniversitesi/Veteriner Fakültesi/Biyometri Anabilim Dalı.; 0000-0002-9018-3511; 0000-0002-9634-0055; JPL-5273-2023; ABE-4828-2020People's awareness of livestock welfare has increased in recent years and veterinarians have a critical role to play in maintaining and improving these standards. The aim of this study was to explore the attitude of veterinary students to livestock welfare and an online questionnaire was utilised to gauge the opinions of students from the Bursa Uludag University Faculty of Veterinary Medicine in Turkey. A five-point Likert scale covered judgments ranging from 'Strongly disagree' to 'Strongly agree.' Female students were found to have a higher score for questions related to the welfare of livestock than males. It was also found that students yet to undertake courses in clinical science and animal welfare, ie first and second years, gave higher scores than third, fourth and fifth years who had completed both of these. Moreover, students having owned or dealt previously with livestock provided lower animal welfare scores than their counterparts who had done neither. Seemingly, the sensitivity of veterinary students decreases during the latter stages of their education. To conclude, we suggest further investigation into the extent to which veterinary medicine education influences students' attitudes to animal welfare as they progress through the course.Publication Evaluation of outlier detection method performance in symmetric multivariate distributions(Taylor & Francis, 2020-02-01) Uzabacı, Ender; Ercan, İlker; Alpu, Özlem; UZABACI, ENDER; ERCAN, İLKER; Bursa Uludağ Üniversitesi/Veteriner Fakültesi/Biyoistatistik Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Biyoistatistik Anabilim Dalı.; 0000-0002-9634-0055; 0000-0002-2382-290X; JPL-5273-2023; ABF-2367-2020Determining outliers is more complicated in multivariate data sets than it is in univariate cases. The aim of this study is to evaluate the blocked adaptive computationally efficient outlier nominators (BACON) algorithm, the fast minimum covariance determinant (FAST-MCD) method, and the robust Mahalanobis distance (RM) method in multivariate data sets. For this purpose, outlier detection methods were compared for multivariate normal, Laplace, and Cauchy distributions with different sample sizes and numbers of variables. False-negative and false-positive ratios were used to evaluate the methods' performance. The results of this work indicate that the performance of these methods varies according to the distribution type.Publication Investigating academic veterinarians' knowledge of biostatistics: A web-based survey(Ankara Üniversitesi, 2015-01-01) Ocakoğlu, Gökhan; Ercan, İlker; Kaya, Mehmet Onur; Uzabacı, Ender; Can, Fatma Ezgi; OCAKOĞLU, GÖKHAN; ERCAN, İLKER; UZABACI, ENDER; Can, Fatma Ezgi; Uludağ Üniversitesi/Tıp Fakültesi/Biyoistatistik Anabilim Dalı; Uludağ Üniversitesi/Veteriner Fakültesi/Biyoistatistik Bölümü; 0000-0002-1114-6051; 0000-0002-2382-290X; 0000-0002-9634-0055; JPL-5273-2023; HLG-6346-2023; AAH-5180-2021; JSL-7718-2023; ABF-2367-2020The primary aim of our study, web-based survey, is to gain an understanding of veterinarians' statistical knowledge and how it varies by focus area. The secondary aim is to address the following question: when should biostatistics be taught in veterinary education? A total of 155 veterinarians from 41 countries participated in this study. The results indicate that while veterinarians place an emphasis on biostatistics education, the majority state that biostatistics education should be taken both at the undergraduate and postgraduate level and the participants also believe that taking a biostatistics course is useful for their occupation. In biostatistics education, the topic of sampling, which plays a significant role at the planning stage of any study, should be considered particularly important. A biostatistics education should also emphasize the necessity of consulting to a biostatistician when planning a study.Publication A survey to identify the Turkish people's approach on animal rights concept: II. Attitude analysis related to animal love, animal identification, animal ownership and eating habits(Kafkas Üniversitesi Veteriner Fakültesi Dergisi, 2013-03-01) Özkul, Türel; Sarıbaş, Taner; Uzabacı, Ender; Yüksel, Erhan; ÖZKUL, TÜREL; UZABACI, ENDER; Uludağ Üniversitesi/Veteriner Fakültesi/Tarihi & Deontoloji Anabilim Dalı; Uludağ Üniversitesi/Veteriner Fakültesi/Biyoistat Anabilim Dalı; 0000-0002-9634-0055; 0000-0003-3966-478X; AAH-2830-2021; JPL-5273-2023The present study was undertaken to determine the Turkish people's cognitive level and perception on the concept of animal rights. For this aim, A questionnaire was developed for collecting data and was applied to participants in seven provinces which are considered to represent geographical regions of Turkey. The survey was applied by interviewing with 2016 participants individually. The responses to the questions of animal love, identification of animals, animal ownership and eating habits are grouped themselves after the evaluation of survey data and analysed statistically. As a results, positive proportion was determined by the parameters of animal love, contact with the animals at home, accepting the animals as an individual and being vegetarian (P<0.001).