Person: BAYKARA, MEHMET
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BAYKARA
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MEHMET
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Publication Intraocular lens elongation technique with haptic modification for sulcus implantation(Galenos Publ House, 2022-08-01) Efe, Ayşe Çetin; BAYKARA, MEHMET; Gündüz, Gamze Uçan; UÇAN GÜNDÜZ, GAMZE; Yurttaş, Ceren; YURTTAŞ, CEREN; Tıp Fakültesi; Oftalmoloji Ana Bilim Dalı; 0000-0002-5555-1649; 0000-0002-5458-1686; AAH-6661-2021Objectives: To define a haptic modification technique to increase the overall length of the intraocular lens (IOL) and evaluate the postoperative outcomes of patients in whom this technique was applied.Materials and Methods: The preoperative and postoperative characteristics of patients who underwent modified IOL implantation into the sulcus between May 2019 and December 2019 were evaluated. Modified Sensar AR40e lenses with hydrophobic acrylic optic and polymethylmethacrylate haptics were implanted to all eyes. Before implanting the IOL, the haptics were grasped with two toothless forceps and bent to elongate the total diameter of the IOL from 13.0 mm to 14.5 mm.Results: The study included 11 eyes of 11 patients who underwent modified three-piece IOL implantation into the sulcus due to insufficient capsular support. The mean age of the patients was 53.9 +/- 12.2 years. The mean axial length was 24.13 +/- 1.93 mm. Sulcus implantation was required due to aphakia in 9 eyes and IOL dislocation in 2 eyes. No haptic breakage occurred during the IOL modification technique or implantation. The mean preoperative best corrected visual acuity (BCVA) was 0.88 +/- 1.1 logMAR, while postoperative BCVA was 0.28 +/- 0.30 logMAR. No IOL dislocation or decentration was observed during 6-month postoperative follow-up.Conclusion: The larger diameter lenses obtained with this inexpensive and easily applicable technique may allow a more stable sulcus implantation in eyes with inadequate capsular support.Publication A modified continuous suturing technique for amniotic membrane fixation after chemical corneal injury: An octagonal graft(Galenos Publ House, 2022-10-01) Baykara, Mehmet; BAYKARA, MEHMET; Sarı, Esin Söğütlü; SÖĞÜTLÜ SARI, ESİN; Yurttaş, Ceren; YURTTAŞ, CEREN; Kırıştıoğlu, Mehmet Ömer; KIRIŞTIOĞLU, MEHMET ÖMER; Tıp Fakültesi; Oftalmoloji Ana Bilim Dalı; 0000-0002-5555-1649; JBU-3309-2023This case report aims to describe a modified continuous suturing technique for firm fixation of a human amniotic membrane graft in a patient with persistent epithelial defect (PED) after a chemical eye injury. As a result of this technique, the amniotic membrane (AM) was firmly fixed to the corneal surface with eight continuous and locked episcleral sutures that resembled an octagon graft. This technique was performed in a 14-year-old patient with PED after a chemical corneal burn. Three weeks after the surgery, the PED was completely healed. This simple continuous suturing technique can allow firm and stable fixation of AM grafts on the ocular surface in cases of PED after chemical burn. It may prevent early loss of the graft and facilitate corneal epithelial wound healing.Publication Evaluation of occupational closed globe eye(Derman Medical Publ, 2015-06-01) Budak, Berna Akova; Kıvanç, Sertaç Argün; KIVANÇ, SERTAÇ ARGUN; Başkaya, Kevser; Baykara, Mehmet; BAYKARA, MEHMET; Yücel, Ahmet Ali; YÜCEL, AHMET ALİ; Tıp Fakültesi; Göz Hastalıkları Ana Bilim Dalı; 0000-0003-0995-5260; 0000-0002-5555-1649; ABE-3033-2020; AAH-6518-2021; ABI-7051-2020Aim: To evaluate closed glob injuries related to occupational accidents of patients who had official occupational accident records. Material and Method: The medical records of patients with ocular injuries who referred to Department of Ophthalmology or emergency of Uludag University, School of Medicine between January 2010 and December 2013 with official occupational accident report were retrospectively reviewed. The patients with closed globe injuries following trauma were included. Age, sex, the injured eye, the cause of the trauma, whether the precautions were taken or not by the patient, the damage due to trauma were recorded. Results: According to the official records, 108 patients referred to our clinic with closed globe injury related to occupational accident. One hundred twenty eyes of 108 patients (2 females, 106 males) were evaluated. The mean age of the patients was 33 +/- 8.6 years. The most frequent cause of injury was foreign bodies on the ocular surface followed by blunt trauma. The mean age of the patients injured with foreign bodies was found to be significantly lower than the patients injured with blunt objects (p=0.039). Thirteen patients reported that they had used preventive equipment. Discussion: It is of utmost importance that the awareness of the workers should be raised and they should be educated about the use of preventive equipment to prevent the occupational eye injuries. The education of particularly the younger patients about the occupational injuries when they begin to work may decrease the rate of occupational accident related eye injuries.Publication Comparison of two techniques in posterior lens dislocations: Scleral suture fixation vs. modified yamane intrascleral lens fixation(Masson Editeur, 2022-01-05) Avcı, R.; Gündüz, G. Uçan; Yıldız, Ayşegül Mavi; Efe, A. Cetin; YALÇINBAYIR, ÖZGÜR; Yalçınbayır, Özgür; BAYKARA, MEHMET; Baykara, Mehmet; Tıp Fakültesi; Göz Hastalıkları Ana Bilim Dalı; 0000-0002-7311-5277; IYJ-9408-2023; ABI-7051-2020Purpose. - To compare the use of Yamane flanged intrascleral haptic fixation and sclera(suture fixation (SSF) techniques in combination with pars plana vitrectomy (PPV) for treatment of posterior lens dislocations.Methods. - Patients who underwent PPV and scleral fixated IOL implantation due to subluxation/luxation of the crystalline lens/intraocular lens (IOL) were included in this retrospective study. The Yamane group included patients who underwent Yamane flanged intrascleral hap tic fixation technique, while the SSF group consisted of patients who underwent conventional SSF. All patients underwent comprehensive ophthalmologic examinations preoperatively and postoperatively. Intraoperative and postoperative complications were recorded.Results. -The Yamane group comprised of 39 eyes of 39 patients, and the SSF group included 35 eyes of 35 patients. Postoperative complications included hyphema (Yamane group: 2 /39 (5.1%); SSF group: 0/35 (0%)) IOL decentration (Yamane group: 5/39 (12.8%); SSF group: 0(35 (0%)), corneal edema (Yamane group: 4/39 (10.2%); SSF group: 0/35 (0%)) cystoid macular edema (CME) (Yamane group: 1/39 (2.5%); SSF group: 3/35 (8.5%)) and retinal detachment (Yamane group: 1/39 (2.5%); SSF group: 1/35 (28.5%). The mean surgery time was significantly lower in the Yamane group compared with the SSF group (P< 0.001). No cases of hypotony, conjunctival erosion, haptic exposure or endophthalmitis were encountered throughout follow-up.Conclusion. - SSF remains a safe and effective technique for management of posterior lens dislocations. The Yamane intrascleral IOL fixation technique is an effective alternative to conventional SSF, which has a relatively steep learning curve. Postoperative complications, including IOL tilt and decentration, may be experienced in the initial cases.Publication Intracorneal ring implantation using Intralase® with partial coverage of the cone in a patient after an alkaline injury(Dove Medical Press Ltd, 2011-01-01) Çakır, Hanefi; Utine, Canan Aslı; Baykara, Mehmet; BAYKARA, MEHMET; Tıp Fakültesi; Göz Hastalıkları Ana Bilim Dalı; ABI-7051-2020Purpose: To report the use of intracorneal ring segment (ICRS) implantation in a case of severe corneal thinning and irregularity secondary to alkali burn.Case report: A 33-year-old man who had a history of ocular alkali burn in the right eye was admitted. His best corrected visual acuity was 0.16 with manifest refraction of +5.00 (-7.00 x 180 degrees). Orbscan II (R) revealed steepening of >53 D superiorly, excessive thinning inferiorly with thinnest pachymetric reading of 269 mu m. Two KeraRing (R) segments, 200 mu m thick and 90 degrees arced, were implanted. During intrastromal channel creation by Intralase (R), the inferior half of the applanating cone was covered by a gelatinous paper to prevent the penetration of the laser beam into the anterior chamber. In the first year postoperation, best corrected visual acuity was 0.7 with manifest refraction of +1.50 (-3.50 x 35 degrees). Visante (R) opticial coherence tomography displayed ICRS at a depth of similar to 370 similar to mu m.Conclusion: ICRS implantation with this novel approach may be an option in eyes with severe corneal irregularity and thinning.Publication Evaluation of intraocular pressure change and anterior segment parameters after intravitreal bevacizumab injection - cannula size matters(Wolters Kluwer Medknow Publications, 2020-10-01) Hamidi, Nagihan A.; Güneş, Irfan B.; Baykara, Mehmet; Baykara, Mehmet; BAYKARA, MEHMET; Tıp Fakültesi; OftalmolojiAna Bilim Dalı; ABI-7051-2020PURPOSE: To determine the changes in intraocular pressure (IOP) and anterior chamber parameters following intravitreal bevacizumab injection with different sizes of cannulas. METHODS: This clinical trial was conducted with 70 eyes of 70 patients who received an intravitreal injection of bevacizumab with 26 G (Group 1) or 30 G (Group 2) needle. Preinjection and postinjection 30th-min IOP and pentacam measurements were obtained. Anterior chamber depth (ACD), anterior chamber volume (ACV), central corneal thickness (CCT), corneal volume (CV), and iridocorneal angle (ICA) measurements were evaluated in pentacam. RESULTS: Preinjection mean IOP values in Group 1 and 2 were 14.7 +/- 3.29 mm Hg and 15.1 +/- 2.87 mm Hg, respectively. Postinjection mean IOP in Group 1 was 16.8 +/- 6.24 mm Hg and in Group 2 was 20.3 +/- 3.66 mm Hg. Postinjection mean IOP values were significantly higher than preinjection values in both groups (Group 1 P < 0.005 and Group 2 P < 0.001). IOP change was significantly higher in Group 2 after injection (P < 0.05). In both groups, the change in IOP found to be more significant in phakic eyes than pseudophakic eyes (Group 1 P < 0.001, Group 2 P < 0.001). CCT and CV were significantly higher in both groups 30 min after the injection than preinjection (Group 1 and Group 2; P < 0.01). In Group 2 ACD, ACV and ICA values were significantly lower than preinjection values (P < 0.05). CONCLUSION: Needle bore size is an important parameter that influences anterior segment parameters and IOP change in the intravitreal injection. IOP rise and anterior segment changes are more prominent with a thinner cannula.Publication Lamina cribrosa curvature index: A reliable parameter to screen diabetic patients for glaucoma(Sage Publications Ltd, 2022-11-04) İlhan, Esin; Tiskaoğlu, Nesime S.; Baykara, Mehmet; BAYKARA, MEHMET; Tıp Fakültesi; Göz Hastalıkları Ana Bilim Dalı; ABI-7051-2020Purpose To compare the translaminar pressure difference (TLPD), anterior lamina cribrosa surface depth (ALCSD), lamina cribrosa thickness (LCT), lamina cribrosa curvature index (LCCI) and peripapillary vascular density (pVD) in diabetic and healthy subjects. Methods Two hundred and eighty eyes of 140 patients (79 patients with diabetes mellitus (DM) without diabetic retinopathy (DR) and 61 healthy subjects) were enrolled in this study. Full ophthalmological examination, as well as optical coherence tomography (OCT) and OCT angiography (OCT-A) images, were analyzed. The ALCSD, LCT, LCCI were measured by enhanced depth imaging (EDI) OCT and the pVD by OCT-A. The TLPD values and relationships between TLPD and lamina cribrosa features and pVD were investigated in all subjects. Results The ALCSD and LCT were significantly shallower and thinner in diabetic patients when compared to healthy subjects (p <0.001). There was no significant difference in the LCCI in diabetics 13.717 (5.74-33.91) vs healthy subjects 13.118 (5.53-27.05) (p = 0.181). OCT-A revealed that the pVD in the diabetic group was significantly lower than in the non-diabetic group (p <0.001). TLPD was significantly lower in diabetic patients compared to healthy controls. Conclusion There are early changes in pVD and peripapillary vessel morphology in patients with DM. ALCSD and LCT were shallower and thinner in diabetic patients whereas the LCCI did not differ significantly. LCCI may be more valuable in assessing the lamina cribrosa (LC) of diabetic patients. The TLPD was found to be lower in diabetic patients compared to normal controls.Publication Acanthamoeba keratitis and acanthamoeba conjunctivitis: A case report(Iranian Scientific Society Medical Entomology, 2020-04-01) Alver, Oktay; Baykara, Mehmet; Yuruk, Merve; Ülkü Tüzemen, Nazmiye; ALVER, OKTAY; BAYKARA, MEHMET; TÜZEMEN, NAZMİYE ÜLKÜ; Tıp Fakültesi; Tıbbi Mikrobiyoloji Ana Bilim Dalı; 0000-0002-5555-1649; AAA-5241-2021; ABI-7051-2020; CGE-2103-2022Acanthamoeba species are vision-threatening agents by causing cornea infections known as Acanthamoeba keratitis. A 5 year-old kid with the complaints of erythema, eyelid edema, inflammation, limitation of eye movements in the right eye, and having no history of wearing contact lenses or trauma, was diagnosed of Acanthamoeba conjunctivitis through laboratory examinations in the Ophthalmology clinic. The visual sharpness of the patient improved after the treatment. A 44 year-old female patient suffering from pain, stinging, irritation, and inability to see in the left eye with the history of wearing contact lenses or trauma was diagnosed of Acanthamoeba keratitis through laboratory examinations. The agent was isolated and identified as "A. castellam" in the Genotype "T2". Examination of the left eye on the 15th day of treatment indicated that all complaints disappeared except for the cataract originated visual loss. However, the first diagnosis of Acanthamoeba keratitis appeared in the literature on a case with no history of wearing contact lenses and trauma it is found to be attention grabbing. We think that Acanthamoeba should not be ignored among microbial agents that cause eye infection with or without trauma and contact lens usage history.Publication Transconjunctival sutureless intrascleral fixation of 3-piece intraocular lenses using a curved needle(Lippincott Williams & Wilkins, 2022-08-01) Genç, Selim; Çakır, Hanefi; Esen, Fehim; Baykara, Mehmet; BAYKARA, MEHMET; Tıp Fakültesi; Oftalmoloji Ana Bilim Dalı; 0000-0003-3049-2571; 0000-0002-5555-1649; 0000-0002-9948-5575; AAA-1283-2022; ABI-7051-2020; M-5848-2017Publication Preparation and characterization of latanoprost-loaded pva nanofibers as an ocular drug delivery system for glaucoma treatment(Taylor & Francis As, 2023-05-15) Karaca, Esra; KARACA, ESRA; Cesur, Merve İlkay Altuntuğ; Osman, Bilgen; OSMAN, BİLGEN; KANMAZ, DİLAYDA; TÜMAY ÖZER, ELİF; Baykara, Mehmet; BAYKARA, MEHMET; Tıp Fakültesi; Oftalmoloji Ana Bilim Dalı; 0000-0001-8406-149X; 0000-0002-5555-1649; 0000-0003-1777-3977; HSI-3968-2023; AAS-8480-2020In this study, latanoprost-loaded polyvinyl alcohol (PVA/LAT) nanofibers were developed as an ocular drug delivery system for glaucoma treatment. The nanofibers were constructed via electrospinning and crosslinked by glutaraldehyde. The characterization studies were conducted by scanning electron microscopy, Fourier Transform infrared spectroscopy, Brunauer, Emmett, and Teller analyses, water contact angle measurements, and also swelling and degradation studies. The PVA/LAT nanofibers crosslinked with 0.5% glutaraldehyde solution for 20 min had a cumulative release of 52% for 23 days. The results demonstrated that the PVA/LAT nanofibers have a usage potential as an ocular drug delivery system for glaucoma treatment.