Person: BALABAN ADIM, ŞADUMAN
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BALABAN ADIM
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ŞADUMAN
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Publication Flow cytometric analysis of T, B, and NK cells antigens in patients with mycosis fungoides(Hindawi, 2015-11-24) Yazıcı, Serkan; Başkan, Emel Bülbül; Budak, Ferah; Oral, Barbaros; Adım, Şaduman Balaban; Kalın, Zübeyde Ceylan; Özkaya, Güven; Aydoğan, Kenan; Sarıcaoğlu, Hayriye; Tunalı, Şükran; YAZİCİ, SERKAN; BÜLBÜL BAŞKAN, EMEL; BUDAK, FERAH; ORAL, HALUK BARBAROS; BALABAN ADIM, ŞADUMAN; Kalın, Zübeyde Ceylan; ÖZKAYA, GÜVEN; AYDOĞAN, KENAN; SARICAOĞLU, HAYRİYE; Tunalı, Şükran; Uludağ Üniversitesi/Tıp Fakültesi/Dermatoloji ve Zührevi Hastalıklar Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/İmmünoloji Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Patoloji Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Biyoistatistik Anabilim Dalı.; 0000-0001-6407-0962; 0000-0001-7625-9148; 0000-0003-0463-6818; 0000-0003-0297-846X; 0000-0002-0193-1128; IZP-9398-2023; AAH-2459-2021; AAH-1388-2021; A-4421-2016; F-4657-2014; AAH-6216-2021; K-7285-2012; EMN-0789-2022; CWV-8710-2022; DPU-8534-2022; GGH-7385-2022We retrospectively analyzed the clinicopathological correlation and prognostic value of cell surface antigens expressed by peripheral blood mononuclear cells in patients with mycosis fungoides (MF). 121 consecutive MF patients were included in this study. All patients had peripheral blood flow cytometry as part of their first visit. TNMB and histopathological staging of the cases were retrospectively performed in accordance with International Society forCutaneous Lymphomas/European Organization of Research and Treatment of Cancer (ISCL/EORTC) criteria at the time of flow cytometry sampling. To determine prognostic value of cell surface antigens, cases were divided into two groups as stable and progressive disease. 17 flow cytometric analyses of 17 parapsoriasis (PP) and 11 analyses of 11 benign erythrodermic patients were included as control groups. Fluorescent labeled monoclonal antibodies were used to detect cell surface antigens: T cells (CD3(+), CD4(+), CD8(+), TCR alpha beta(+), TCR gamma delta(+), CD7(+), CD4(+) CD7(+), CD4(+) CD7(-), and CD71(+)), B cells (HLA-DR+, CD19(+), and HLA-DR(+)CD19(+)), NKT cells (CD3(+)CD16(+)CD56(+)), and NK cells (CD3(-)CD16(+)CD56(+)). The mean value of all cell surface antigens was not statistically significant between parapsoriasis and MF groups. Along with an increase in cases of MF stage statistically significant difference was found between the mean values of cell surface antigens. Flow cytometric analysis of peripheral blood cell surface antigens in patients with mycosis fungoides may contribute to predicting disease stage and progression.Publication A challenging case: Multiple and blaschkoid hair follicle naevi or supernumerary accessory tragi?(Wiley, 2019-05-01) Sarıcaoğlu, Hayriye; Zorlu, Özge; Adım, Şaduman Balaban; Demirkesen, Cuyan; SARICAOĞLU, HAYRİYE; Zorlu, Özge; BALABAN ADIM, ŞADUMAN; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Dermatoloji ve Zührevi Hastalıklar Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Patoloji Anabilim Dalı.; 0000-0001-5555-130X; ABD-1191-2021; DPU-8534-2022; EMN-0789-2022Publication Tuberculosis of the sclera(Turkish Ophthalmological Soc, 2008-07-01) Eser, İlker; UÇAN GÜNDÜZ, GAMZE; Uçan, Gamze; Yazıcı, Bulent; Adım, Saduman Balaban; BALABAN ADIM, ŞADUMAN; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Patoloji Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Göz Hastalıkları Anabilim Dalı.; 0000-0002-5458-1686; 0000-0001-8889-1933; AAA-5384-2020; AAH-6661-2021A 53-year-old female patient who presented with an inflamated scleral mass was diagnosed as scleral tuberculosis as a result of histopathologic evaluation. Systemic evaluation showed no evidence of tuberculosis. The patient received a multi-drug anti-tuberculosis treatment for 9 months. After treatment, all ocular symptoms improved and no recurrence occurred in the 22 months following the treatment. Scleral tuberculoma should be considered in patients presented with an inflammated mass in the sclera. In some cases, histopathological findings and positive response to the medical treatment may be sufficient for the diagnosis.Publication Efficacy of 0.1% tacrolimus ointment in chronic plaque psoriasis: A randomized double-blind placebo-controlled study(Deri Zuhrevi Hastaliklar Dernegi, 2015-01-01) Kaçar, Seval Dogruk; Kaçar, Emre; Baskan, Emel Bulbul; BÜLBÜL BAŞKAN, EMEL; Bolca, Naile; BOLCA TOPAL, NAİLE; Adım, Sadiman Balaban; BALABAN ADIM, ŞADUMAN; Tunalı, Şükran; Sarıcaoğlu, Hayriye; SARICAOĞLU, HAYRİYE; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Deri ve Zührevi Hastalıkları Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Tıbbi Patoloji Anabilim Dalı.; JLM-2426-2023; AAH-1388-2021Background and Design: Despite the development of effective systemic treatments and new biological agents for psoriasis nowadays, topical medications are still the mainstay of treatment. Topical calcineurin inhibitors are currently used in various skin diseases. We investigated the efficacy and safety of tacrolimus, which is an alternative in topical treatment, in comparison with the present medications in plaque psoriasis.Materials and Methods: This prospective double-blind placebo-controlled study was conducted in 24 patients with the diagnosis of plaque psoriasis who were seen in Uludag University Hospital dermatology outpatient clinic. 0.1% tacrolimus ointment, 0.1% mometasone furoate ointment, 0.005% calcipotriol ointment and placebo in encrypted bottles were randomly applied under occlusion to 27 psoriatic plaques in test chambers, every other day, for a period of 19 days. Clinic sum scores, side effects, and epidermal thickness measured by superficial ultrasound were noted before and after treatment in all microplaques. Besides, histopathologic scoring and epidermal thickness were measured in 9 patients at the end of the study.Results: The clinic sum scores and ultrasonographic epidermal thickness at the end were both significantly lower than the beginning values in all microplaques (p<0.05). The reduction in these two values with tacrolimus were significantly higher than that with placebo (p<0.001), but no difference was observed with calcipotriol (p=0.287, p=0.813, respectively). On the other hand, the reduction in these values with mometasone was significantly higher than with tacrolimus (p<0.05). Mometasone furoate was the most effective when the three ointments were compared with placebo in terms of total histopathological score and epidermal thickness.Conclusion: Tacrolimus ointment applied under occlusion is an alternative topical medication in the treatment of plaque psoriasis. Occlusion in practice requires patient compliance. Thus, studies to find a new formulation that will increase absorption of drug from thick psoriatic plaques are needed.Publication Palpebral tarsal solitary neurofibroma(Turkish Ophthalmological Soc, 2019-08-01) Yazıcı, Bülent; Kıvanç, Sertaç Argün; KIVANÇ, SERTAÇ ARGUN; Yayla, Uğur; Adım, Saduman Balaban; BALABAN ADIM, ŞADUMAN; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Oftalmoloji Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Patoloji Anabilim Dalı.; 0000-0001-8889-1933; AAA-5384-2020; AAH-6518-2021; JCE-2538-2023Solitary neurofibroma is a rare, benign tumor of the peripheral nerve sheath, and is often associated with neurofibromatosis type 1. Herein, a case of palpebral tarsal solitary neurofibroma in a patient without neurofibromatosis is presented, with a review of the literature. A 68-year-old man presented with a subcutaneous mass in the right upper eyelid of 6 months' duration. Eversion of the eyelid revealed a round, reddish mass on the lateral part of the tarsal plate which measured 12x8 mm in size. The lesion was excised with its tarsal base, diagnosed histologically, and did not recur during a follow-up of 34 months. Isolated, solitary neurofibroma of the eyelid has been reported in a total of 7 cases, including the case presented herein. The tumors arose from the eyelid margin in 4 cases, from the tarsal plate in 2 cases, and from the supratarsal conjunctiva in 1 case. The tumor did not recur after surgical excision in 5 cases for which follow-up data were available.Publication An unusual reason of parotid gland enlargement; parotid gland tuberculosis(Turkish Assoc Tuberculosis & Thorax, 2006-01-01) Çakır, Ümit; Erdoğan, Beril; Uzaslan, Esra; UZASLAN, AYŞE ESRA; Demirdöğen, Ezgi; DEMİRDÖĞEN, EZGİ; Adım, Saduman Balaban; BALABAN ADIM, ŞADUMAN; Salan, Arzu; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Hastalıkları Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Patoloji Anabilim Dalı.; 0000-0002-7400-9089; JPK-7012-2023; AAI-1004-2021; AAH-9812-2021Although pulmonary tuberculosis is common in Turkey, parotid gland tuberculosis is rarely seen. A 39 years old female presented with left side swelling on her face. The diagnosis was made excisional biopsy. Histologic examination of the operative specimen revealed necrotising granuloma concordant with tuberculosis.Publication A case of mycosis fungoides-like lesions developing after levetiracetam therapy(Elsevier Science Inc, 2014-01-01) Bora, İbrahim; BORA, İBRAHİM HAKKI; BİCAN DEMİR, AYLİN; Başkan, Emel Bülbül; BÜLBÜL BAŞKAN, EMEL; Demir, Aylin Bican; Balaban, Şaduman; BALABAN ADIM, ŞADUMAN; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Nöroloji Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Dermatoloji Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Patoloji Anabilim Dalı.; 0000-0001-6739-8605; V-7170-2017; JCE-6657-2023; AAH-1388-2021Levetiracetam is a relatively new antiepileptic drug that has previously not been associated with severe dermatological side effects. We report the case of a 31-year-old male treated with levetiracetam for seizures who subsequently developed a mycosis fungoides-like drug reaction that resolved upon dosage reduction. (C) 2014 Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license.Publication Keloid formation following ear piercing through the transitional zone(Elsevier Science Inc, 2023-06-30) Zorlu, Özge; Yazıcı, Serkan; Adım, Şaduman Balaban; Zorlu, Özge; YAZİCİ, SERKAN; BALABAN ADIM, ŞADUMAN; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Dermatoloji ve Zührevi Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Patoloji Anabilim Dalı.; 0000-0001-5555-130X; 0000-0001-6407-0962; IAL-9735-2023; EHG-3420-2022; EMN-0789-2022Publication Erythema nodosum epidemiology: 5-year retrospective study(Wolters Kluwer Medknow Publications, 2012-09-01) Öz, Arife; Aydoğan, Kenan; Adım, Saduman Balaban; İzol, Belçin; Sarıcaoğlu, Hayriye; Başkan, Emel Bülbül; Tunalı, Şükran; Öz, Arife; AYDOĞAN, KENAN; BALABAN ADIM, ŞADUMAN; SARICAOĞLU, HAYRİYE; BÜLBÜL BAŞKAN, EMEL; Tunalı, Sükran; Uludağ Üniversitesi/Tıp Fakültesi/Deri ve Zührevi Hastalıklar Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Patoloji Anabilim Dalı.; 0000-0002-0144-3263 ; JQC-1664-2023; AAH-6216-2021; EMN-0789-2022; DPU-8534-2022; AAH-1388-2021; GGH-7385-2022Objective: Erythema nodosum (EN) is the most common type of septal panniculitis. Although triggering factors of EN are drugs, infections, malignancies, inflammatory diseases however disease is idiopathic in 32-72%. Factors are changing from region to region and from country to country. In this study, our aim was to investigate the etiologic factors and to evaluate the clinic and laboratory findings of EN.Methods: Sixty-six patients who were histopathologically diagnosed as EN in our department between 2005 and 2010 were included to this study. Demographic data and treatment were evaluated.Results: Fifty-two of 66 patients had underlying etiologic factors (Group 1) and 14 of were idiopatic (Group 2). Most common etiologic factor was Behcet's disease (n=15), and followed by drug (n=13), sarcoidosis (n=10), upper respiratory tract infection (n=6), autoimmune disease (n=4), pregnancy (n=2), tuberculosis (n=2) in decreasing frequencies. In our study malignancy and inflammatory bowel disease are not appointed.Conclusion: Behcet's disease is a rare cause of EN. In other studies in our country the idiopatic group was in majority. In our study because of finding the common etiologic factor as Behcet's disease due to being of Behcet's disease high prevalance (11-42/10000) in our country and existence of Behcet's disease center in our facultyPublication Periocular pilomatrixoma(Turkish Ophthalmological Soc, 2010-05-01) Çakırlı, Ebru; Yazıcı, Bülent; Adım, Şaduman Balaban; BALABAN ADIM, ŞADUMAN; Gönen, Tansu; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Göz Hastalıkları Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Patoloji Anabilim Dalı.; 0000-0001-8889-1933; AAA-5384-2020Pilomatrixoma is a rare tumor of hair-follicle origin. It occurs most commonly in the cheek and neck region, and in young patients, but rarely develops on or around the eyelids. Because of its clinical features, pilomatrixoma is often confused with other skin tumors. In this report, we present 4 patients with periocular pilomatrixoma diagnosed in our clinic in a period of 6 years. The patients, three female and one male, were 8, 23, 55 and 83 years of age. The lesions were located in the upper eyelid in 2 patients, in the inferior periorbital region in 1 patient, and in the medial periorbital region in 1 patient. After surgical excision and repair, tumor recurrence did not develop in any patient throughout the follow-up period.