Person: UZASLAN, AYŞE ESRA
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UZASLAN
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AYŞE ESRA
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Publication Attitude and practice toward use of cigarettes and electronic cigarettes among pregnant women: A Questionnaire-based survey(Aves, 2022-11-01) Yıldırım, Elif; Duru, Serap; Sevim, Tülin; Topçu, Füsun; Gemicioglu, Bilun; Özmen, İpek; Ocaklı, Birsen; Tuncay, Eylem; Altınöz, Hilal; Akpak, Yaşam Kemal; Çelik, Pınar; Varol, Yelda; Polat, Gulru; Özkan, Serir; Dursunoğlu, Neşe; Kılıç, Derya; Gülhan, Pınar Yıldız; Diken, Özlem Ercen; Cetinkaya, Pelin Duru; Yorgancıoğlu, Arzu; Selçuk, Nursel Türkoğlu; Yıldız, Füsun; Ataçağ, Tijen; Niksarlıoğlu, Elif Yelda; Uzaslan, Esra; Köktürk, Nurdan; UZASLAN, AYŞE ESRA; Tıp Fakültesi; Göğüs Hastalıkları Ana Bilim Dalı; CDI-1977-2022OBJECTIVE: This study aimed to evaluate attitude and practice toward use of regular tobacco cigarettes and electronic cigarettes among pregnant women.MATERIAL AND METHODS: A total of 1123 pregnant women participated on a voluntary basis in this questionnaire survey. Maternal characteristics, cigarette consumption parameters, and personal opinions regarding the adverse effects of smoking during pregnancy were evaluated.RESULTS: Active smokers composed 12.4% (9.4%: regular tobacco cigarettes, 3.0%: electronic cigarettes) of the study population. Smoking during the current pregnancy, particularly via regular tobacco cigarettes, was more likely for women with smoking during previous pregnancies (56.0% vs. 7.8%, P <.001), previous history of low birth weight infant delivery (16.1% vs. 8.6%, P =.013), premature delivery (16.7% vs. 7.0%, P <.001), and stillbirth (22.8% vs. 11.7%, P =.002). The presence versus absence of smoking during pregnancy was associated with a lower likelihood of being a housewife (70.5% vs. 80.5%, P =.010) and a higher likelihood of having an actively smoking mother (25.9% vs. 11.2%, P <.001) or partner (65.7% vs. 46.9%, P <.001). Regular tobacco cigarette users considered electronic cigarettes to have a higher risk of adverse impacts (11.1% vs. 2.9%, P =.012), while electronic cigarette users considered regular cigarettes to have a higher risk of nicotine exposure (55.9% vs. 13.0%, P <.001).CONCLUSION: Our findings indicate being employed, having an actively smoking mother or partner, as well as smoking in previous pregnancies, to be the risk factors for increased likelihood of smoking during pregnancy.Publication The importance of gender factor in evaluation of spirometric and nutritional parameters in patients with stable COPD(Kare Yayınevi, 2009-12-01) Göçmen, Hayrettin; Ediger, Dane; Uzaslan, Esra; Ertem, Arzu; Ege, Ercüment; Göçmen, Hayrettin; EDİGER, DANE; UZASLAN, AYŞE ESRA; Ertem, Arzu; Ege, Ercüment; Tıp Fakültesi; Göğüs Hastalıkları Ana Bilim Dalı; 0000-0002-2954-4293; AAI-1004-2021; AAE-9142-2019; JLE-1834-2023; CNR-8456-2022; CPF-5844-2022Aim: We aimed to evaluate the relationship between sex factor, spirometric and nutritional parameters in patients with stable COPD.Material and methods: Patients with stable COPD who had no additional problem that affects spirometric and nutritional results, were included in the study. By the application of SGRQ questionnarie nutritional parameters, spirometric and demographic findings of cases were recorded and evaluated.Results: Totally 100 patients with stable COPD (81 males, 19 females and mean age 65.1 +/- 4.3 years) were evaluated prospectively. % FEV1 (p=0.003), % FEF25-75 (p=0.011), % PEF (p=0.003) values and smoking package-years (p=0.009) were found significantly higher in males. Body Mass Index values were significantly higher (p=0.018) in females (30.7 +/- 6.6) than males (27.4 +/- 4.9). In males higher triceps skin thickness values (p<0.001) and lower SGRQ scores (p=0.036) were found.Conclusion: Smoking is the most important agent in devoloping of COPD. Although smoking duration was shorter in females spirometric findings were worse. In spite of this finding, because of better nutritional parameters and lower SGRQ scores, it is thought that there is insensitivity in females to systemic response.Publication Association of fatigue with mental well-being, quality of life and exercise capacity in sarcoidosis: A case-control comparision(Amer, 2015-01-01) Dilektaşlı, Aslı Görek; Çetinoğlu, E. Demirdöğen; Acet, N. Aylin; Gökmen, Nilüfer E.; Karadağ, Mehmet; Uzaslan, Esra; GÖREK DİLEKTAŞLI, ASLI; Çetinoğlu, E. Demirdöğen; ACET ÖZTÜRK, NİLÜFER AYLİN; KARADAĞ, MEHMET; UZASLAN, AYŞE ESRA; Tıp Fakültesi; 0000-0001-7099-9647; 0000-0002-7400-9089; 0000-0002-6375-1472; 0000-0002-9027-1132; Z-1424-2019; JPK-7012-2023; AAG-8744-2021; DTT-7416-2022; AAH-9812-2021; Z-1424-2019; CQV-5946-2022; CDI-1977-2022Publication Frailty: An indicator for poor outcomes among in-hospital pulmonology patients(European Respiratory Soc Journals, 2021-09-05) Öztürk, Nilüfer Aylin Acet; Dilektaşlı, Aslı Görek; Güçlü, Özge Aydın; Ursavaş, Ahmet; Demirdoğen, Ezgi; Coşkun, Funda; Uzaslan, Esra; Karadağ, Mehmet; ACET ÖZTÜRK, NİLÜFER AYLİN; GÖREK DİLEKTAŞLI, ASLI; AYDIN GÜÇLÜ, ÖZGE; URSAVAŞ, AHMET; DEMİRDÖĞEN, EZGİ; COŞKUN, NECMİYE FUNDA; UZASLAN, AYŞE ESRA; KARADAĞ, MEHMET; Tıp Fakültesi; Göğüs Hastalıkları Ana Bilim Dalı; 0000-0002-6375-1472; 0000-0003-1005-3205; 0000-0002-7400-9089; 0000-0003-3604-8826; 0000-0002-9027-1132; AAI-3169-2021; JPK-7012-2023; AAG-8744-2021; AAD-1271-2019; Z-1424-2019; CNP-1063-2022; AAG-9930-2019; CDI-1977-2022Publication Real life profile of asthma and chronic obstructive pulmonary disease patients in Turkey(Tüberküloz ve Toraks, 2017-01-01) Mısırlıgil, Zeynep; Cimrin, Arif; Günen, Hakan; Özlü, Tevfik; Çilli, Aykut; Akyıldız, Levent; Bayram, Hasan; Gemicioğlu, Bilun; Uzaslan, Esra; Abadoğlu, Öznur; Suerdem, Mecit; Uzaslan, Esra; UZASLAN, AYŞE ESRA; Tıp Fakültesi; Göğüs Hastalıkları Ana Bilim Dalı; AAI-1004-2021Introduction: Despite the presentation of similar symptoms, the airway diseases have different underlying pathophysiological processes and must be distinguished to enable the administration of appropriate treatment. In several studies the clinician-and patient-related causes of poor compliance to treatment in asthma/chronic obstructive pulmonary disease (COPD) patients have been evaluated. This study aimed to determine the clinical and sociodemographic characteristics of newly diagnosed treatment-naive asthma and COPD patients in Turkey.Materials and Methods: This national, multicentre, prospective, observational study was conducted in 122 centres. A questionnaire including items related to demographic, clinical, laboratory parameters was applied. All patients were intended to be followed-up for 12 months.Results: 1892 adult patients (1116 asthma and 776 COPD) from 122 centres were enrolled. Overall 95%,86% and 65% of intermittent, mild persistent and moderate persistent asthma patients were over-treated. Among COPD patients, the percentages of over-treated patients were 66%, 79% and 82% for those with GOLD stage A, B and C. Physicians' adherence to guidelines was appropriate in 93% of severe persistent asthma patients and 89% of GOLD stage D COPD patients. Among patients with high compliance to treatment, proportion of asthma patients with total control was 44% and that of COPD patients at GOLD stage A was 41%. In consecutive two visits, this figure increased to 52% and 63% in asthma patients and 54% and 50% in COPD patients.Conclusion: The main findings are: (a) patients are frequently over-treated and (b) patients do not adhere to visits as expected, in both asthma and COPD.Publication Attitudes and beliefs about copd: Data from the breathe study(W B Saunders Co Ltd, 2012-12-01) Sayiner, Abdullah; Alzaabi, Ashraf; Obeidat, Nathir M.; Nejjari, Chakib; Beji, Majed; Uzaslan, Esra; Nafti, Salim; Khan, Javaid Ahmed; Tageldin, Mohamed Awad; Idrees, Majdy; Rashid, Nauman; El Hasnaoui, Abdelkader; BREATHE Study Grp; UZASLAN, AYŞE ESRA; Tıp Fakültesi; 0000-0001-9610-8507; AAI-1004-2021Although COPD is a debilitating pulmonary condition, many studies have shown awareness of the disease to be low. This article presents data on attitudes and beliefs about COPD in subjects with respiratory symptoms participating in the BREATHE study in the Middle East and North Africa region. This study was a large general population survey of COPD conducted in ten countries of the region (Algeria, Egypt, Jordan, Lebanon, Morocco, Saudi Arabia, Syria, Tunisia, Turkey and United Arab Emirates), together with Pakistan, using a standardised methodology. A total of 62,086 subjects were screened, of whom 2,187 fulfilled the "epidemiological" definition of COPD. A detailed questionnaire was administered to these subjects, which documented knowledge about the disease, attitudes to care, beliefs about COPD and satisfaction with treatment. 1,392 subjects were analysable. Overall, 58.6% of subjects claimed to be very well or adequately informed about their respiratory condition. Two-thirds of subjects reported receiving information about COPD from their physician and 10.6% from television; the internet was cited by 6% and other health professionals or patient associations by <1%. Several inappropriate beliefs were identified, with 38.9% of respondents believing that there were no truly effective treatments, 73.7% believing that their respiratory condition would get progressively worse regardless of treatment and 29.6% being unsure what had caused their respiratory problems. Although 81% of respondents believed that smoking was the cause of most cases of COPD in general, only 51% accepted that it was the cause of their own respiratory problems. Treatment satisfaction was relatively high, with 83.2% of respondents somewhat or very satisfied with their physician's management, in spite of the fact that only 47.5% considered that their physician's advice had helped them manage their respiratory symptoms a lot. In conclusion, awareness of COPD in the region is suboptimal and treatment expectations are undervalued. Better patient education and more effective patient physician communication are clearly required. (C) 2012 Elsevier Ltd. All rights reserved.Publication Impact of covid-19 pneumonia on pulmonary function, functional exercise capacity and quality of life(European Respiratory Soc Journals, 2021-09-05) Dilektasli, Asli Gorek; GÖREK DİLEKTAŞLI, ASLI; Ozturk, Nilufer; ACET ÖZTÜRK, NİLÜFER AYLİN; Odabas, Ayten; Demirdogen, Ezgi; DEMİRDÖĞEN, EZGİ; Ursavas, Ahmet; URSAVAŞ, AHMET; Coskun, Funda; COŞKUN, NECMİYE FUNDA; Guclu, Ozge Aydin; AYDIN GÜÇLÜ, ÖZGE; Ediger, Dane; EDİGER, DANE; Uzaslan, Esra; UZASLAN, AYŞE ESRA; Tıp Fakültesi; 0000-0002-7400-9089; 0000-0003-3604-8826; 0000-0003-1005-3205; 0000-0002-2954-4293; AAI-3169-2021; AAE-9142-2019; JPK-7012-2023; AAD-1271-2019Publication Evaluation of fibrinogen levels in patients with obstructive sleep apnea syndrome(Wiley, 2013-11-01) Çetinoğlu, Ezgi Demirdoğen; Ursavaş, Ahmet; Karadağ, Mehmet; Coşkun, Funda; Ediger, Dane; Uzaslan, Esra; Ege, Ercüment; Gözü, Oktay; Çetinoğlu, Ezgi Demirdoğen; URSAVAŞ, AHMET; KARADAĞ, MEHMET; COŞKUN, NECMİYE FUNDA; EDİGER, DANE; UZASLAN, AYŞE ESRA; Ege, Ercüment; Gözü, Oktay; Tıp Fakültesi; Göğüs Hastalıkları Ana Bilim Dalı; 0000-0002-7400-9089; 0000-0002-9027-1132; 0000-0003-3604-8826; 0000-0002-2954-4293; AAI-3169-2021; AAD-1271-2019; AAG-8744-2021; JPK-7012-2023; AAE-9142-2019; AAH-9812-2021; CDI-1977-2022; CPF-5844-2022; JLC-5863-2023Publication Coexistence of sarcoidosis and sjogren's syndrome: A case-report(Amer, 2015-10-01) Dilektaşlı, Aslı Görek; Çetinoğlu, Ezgi Demirdoğen; Durmuş, Eda; Uzaslan, Esra; Ege, Ercüment; Karadağ, Mehmet; GÖREK DİLEKTAŞLI, ASLI; Çetinoğlu, Ezgi Demirdoğen; Durmuş, Eda; UZASLAN, AYŞE ESRA; Ege, Ercüment; KARADAĞ, MEHMET; Tıp Fakültesi; Göğüs Hastalıkları Ana Bilim Dalı; 0000-0001-7099-9647; 0000-0002-7400-9089; 0000-0002-9027-1132; AAG-8744-2021; JPK-7012-2023; DTT-7416-2022; ETU-0442-2022; CDI-1977-2022; CPF-5844-2022Publication AVAPS-NIV treatment in hypercapnic respiratory failure with insufficient response to fixed-level PS-NIV(Türk Tüberküloz ve Toraks, 2022-01-01) Öztürk, Nilüfer Aylın Acet; Güçlü, Özge Aydın; Demirdöğen, Ezgi; Dilektaşlı, Asli Görek; Maharramov, Shahriyar; Coşkun, Funda; Uzaslan, Esra; Ursavaş, Ahmet; Karadağ, Mehmet; ACET ÖZTÜRK, NİLÜFER AYLİN; AYDIN GÜÇLÜ, ÖZGE; DEMİRDÖĞEN, EZGİ; GÖREK DİLEKTAŞLI, ASLI; Maharramov, Shahriyar; COŞKUN, NECMİYE FUNDA; UZASLAN, AYŞE ESRA; URSAVAŞ, AHMET; KARADAĞ, MEHMET; Tıp Fakültesi; Göğüs Hastalıkları Ana Bilim Dalı; 0000-0002-6375-1472; 0000-0003-1005-3205; 0000-0002-7400-9089; 0000-0001-7099-9647; 0000-0003-3604-8826; 0000-0002-9027-1132; AAI-3169-2021; AAD-1271-2019; AAG-8744-2021; JPK-7012-2023; DTT-7416-2022; DDT-7334-2022Introduction: Noninvasive ventilation (NIV) for acute hypercapnic respiratory failure (AHRF) is an established treatment modality. Current evidence does not conclude any superiority between fixed pressure support (PS) and aver-age volume-assured pressure support (AVAPS) modes. However, given the ability of rapid PaCO2 decline in AVAPS mode, we hypothesized that COPD patients with AHRF who did not show the desired reduction in PaCO2 with fixed-level PS-NIV might benefit from the AVAPS mode.Materials and Methods: Patients admitted to the non-ICU pulmonary ward with acute exacerbation of COPD (AECOPD) and AHRF were included con-secutively in this observational study. Patients with hypercapnic respiratory failure due to obesity-hypoventilation, neurological diseases, or chest wall deformities were excluded. All patients started NIV treatment with fixed pres-sure support (PS) and patients who did not reach clinical and laboratory stability under PS-NIV treatment were switched to the average volume -as-sured pressure support (AVAPS) mode of NIV.Results: Thirty-five COPD patients with hypercapnic respiratory failure were included. Under PS-NIV treatment, 14 (40%) patients showed a 17.9 (-0.0-29.2) percent change in terms of PaCO2 , meaning no improvement or worsening. Therefore, these patients were treated with AVAPS mode. Arterial PaCO2 and pH levels significantly improved after AVAPS-NIV administration. AVAPS-NIV treatment created a significantly better PaCO2 change rate than using PS-NIV (-11.4 (-22.0 --0.5)vs 8.2 (-5.3-19.5), p= 0.02]. Independent predictors of AVAPS mode requirement were higher Charlson Comorbidity Index (OR= 1.74 (95% CI= 1.02-2.97)] and higher PaCO2 upon admission (OR= 1.18 (95% CI= 1.03-1.35)]. Thirteen (92.8%) patients reaching signif-icant clinical stability with AVAPS-NIV were able to return to fixed-level PS-NIV and maintain acceptable PaCO2 levels.Conclusion: Our study demonstrated that patients can benefit from AVAPS-NIV despite insufficient response to fixed-level PS-NIV.