Person: AKYILDIZ, ELİF ÜLKER
Loading...
Email Address
Birth Date
Research Projects
Organizational Units
Job Title
Last Name
AKYILDIZ
First Name
ELİF ÜLKER
Name
12 results
Search Results
Now showing 1 - 10 of 12
Publication Bronchial carcinoid tumors with massive osseous metaplasia: A case report and review of the literature(Türk Patoloji Derneği, 2020-05-01) Özşen, Mine; Yalçınkaya, Ulviye; Akyıldız, Elif Ülker; Bayram, Ahmet Sami; Gökalp, Gökhan; YALÇINKAYA, ÜLVİYE; AKYILDIZ, ELİF ÜLKER; BAYRAM, AHMET SAMİ; GÖKALP, GÖKHAN; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Cerrahi Patoloji Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Cerrahisi Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı.; 0000-0002-5771-7649; 0000-0003-0684-0900; JHY-9777-2023 ; AAI-2336-2021; ABB-7580-2020; AAH-8924-2021Bronchial carcinoid tumors are primary lung neoplasms thought to originate from neuroendocrine cells, i.e. Kulchitsky cells, in the bronchial mucosa, although the type of cellular origin has not been clearly understood. A 61-year-old male patient underwent surgery and microscopic examination of the specimen revealed an anastomosing trabecular bony structure among the nests of tumor cells with round nucleus, granular chromatin, and large eosinophilic cytoplasm. Our case has been deemed worthy of being presented as bronchial carcinoid tumor with exaggerated osseous metaplasia.Publication Immunoglobulin g4-related disease presenting as a mass in the lung(Turkish League Against Rheumatism, 2021-06-24) Akyol, Sevda; Hasdemir, Seçil; Akyıldız, Elif Ülker; AKYILDIZ, ELİF ÜLKER; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Patoloji Anabilim Dalı.Publication Thoracic neurogenic tumors: A clinicopathologic evaluation of 42 cases(Asean Neurological Assoc, 2015-03-01) Akyıldız, Elif Ülker; Yalçınkaya, Ülviye; AKYILDIZ, ELİF ÜLKER; YALÇINKAYA, ÜLVİYE; Uludağ Üniversitesi/Tıp Fakültesi/Patoloji Bölümü; AAH-8924-2021; ELN-4128-2022Background & Objective: Neurogenic tumors typically originate from the peripheral nerves, paraganglionic nerves, or the autonomic nervous system. Tumors arising from peripheral nerves are classified as schwannoma, neurofibroma, and malignant peripheral nerve sheath tumors while tumors arising from the sympathetic chain ganglion cells are classified as ganglioneuroma, ganglioneuroblastoma, and neuroblastoma. Tumors arising from the parasympathetic chain ganglion cells are classified as paraganglioma. Neurogenic tumors of the thorax are uncommon and originate from large airways, lungs, the mediastinum, or the chest wall. In this study, we report the clinical and histopathological features of 42 patients diagnosed with neurogenic tumors of the thorax. Methods: A retrospective review of the medical records of 42 patients diagnosed with intrathoracic neurogenic tumors and treated in Uludag University between 2002 and 2012 was conducted. All pathology specimens were examined by a pathologist experienced in the examination of soft tissue tumors. The patients were evaluated according to age, gender, location and histological characteristics of the tumor. Results: The study group included 42 patients diagnosed thoracic neurogenic tumors, including 31 female (74%) and 11 male (26%). The sex ratio was 2.8 (female/male) and the mean age of the study population was 38.52 years. The age of patients ranged from 3 to 73 years. The neurogenic tumor was located in the posterior mediastinum in 31(74%) patients, anterior mediastinum in 2 (5%) patients, and in the chest wall in 9 (21%) patients. The origin of the neurogenic tumor was the peripheral nerve sheath in 31 (74%) patients, and the ganglion cells in 10 (24%) patients, and the paraganglion system in 1 (2%) patient. The study group also included 20 (48%) patients diagnosed with schwannoma, 6 (14%) patients diagnosed with malignant peripheral nerve sheath tumor, 5 (12%) patients diagnosed with neurofibroma, 5 (12%) patients diagnosed with ganglioneuroma, 4 (10%) patients diagnosed with neuroblastoma, 1 (2%) patient diagnosed with ganglioneuroblastoma and 1 (2%) patient diagnosed with paraganglioma. Our study group comprised 36 adults and 6 children. Of the adult patients, 20 (55%) had schwannomas, 6 (17%) malignant peripheral nerve sheath tumor, 5 (14%) neurofibroma, 4 (11%) ganglioneuromas, and 1 (3%) paraganglioma. Four of the six children (66%) included in our study group were diagnosed with neuroblastoma, 1 (17%) child was diagnosed with ganglioneuroma, and 1 (17%) child was diagnosed with ganglioneuroblastoma. The malignancy rate was 83% in children and 17% in adults.Conclusion: Age is an important clinical parameter in terms of histological type and malignancy rate. In our study group, malignancy rate in children was much higher than adults. The most common thoracic neurogenic tumor in adults and children was schwannoma and neuroblastoma, respectively.Publication Diagnostic value of cervical mediastinoscopy: Report of 506 cases(European Respiratory, 2013-09-01) Erol, Mehmet; Melek, Hüseyin; Bayram, Ahmet; Kermenli, Tayfun; Coşkun, Funda; Akyıldız, Elif; Gebitekin, Cengiz; Erol, Mehmet; MELEK, HÜSEYİN; BAYRAM, AHMET SAMİ; Kermenli, Tayfun; COŞKUN, NECMİYE FUNDA; AKYILDIZ, ELİF ÜLKER; GEBİTEKİN, CENGİZ; Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Cerrahisi Kliniği; Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Hastalıkları Bölümü; Uludağ Üniversitesi/Tıp Fakültesi/Patholoji Bölümü; 0000-0003-0684-0900; 0000-0002-7371-4026; 0000-0003-3604-8826; AAE-1069-2022; AAD-1271-2019; AAI-5039-2021; JCE-0097-2023; ABB-7580-2020; KHO-7454-2024; A-6612-2019; IAV-7890-2023Publication Diagnostic value of video-assisted thoracoscopic lung biopsy on diagnosis of diffuse parenchymal lung dissease(European Respiratory, 2013-09-01) Bayram, Ahmet Sami; Melek, Hüseyin; Erol, Mehmet Muharrem; Coşkun, Funda; Akyıldız, Elif Ülker; Gebitekin, Cengiz; BAYRAM, AHMET SAMİ; MELEK, HÜSEYİN; Erol, Mehmet Muharrem; COŞKUN, NECMİYE FUNDA; AKYILDIZ, ELİF ÜLKER; GEBİTEKİN, CENGİZ; Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Cerrahisi Anabilim Dalı; Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Bölümü; 0000-0003-0684-0900; 0000-0003-3604-8826; JCE-0097-2023; AAE-1069-2022; AAI-5039-2021; ABB-7580-2020; AAD-1271-2019; KHE-8874-2024; JHY-9777-2023Publication Pulmonary sclerosing hemangioma exhibiting a high KI-67 proliferation index(Erciyes Üniversitesi, 2012-04-17) Akyıldız, Elif Ülker; Bayram, Sami; Arıcı, Akgül; Kasap, Mehtap; AKYILDIZ, ELİF ÜLKER; BAYRAM, AHMET SAMİ; Arıcı, Akgül; Kasap, Mehtap; Uludağ Üniversitesi/Tıp Fakültesi/Patoloji Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Torasik Cerrahi Anabilim Dalı.; ABB-7580-2020; JHY-9777-2023; EKW-8583-2022; FDC-3047-2022Pulmonary sclerosing hemangioma (PSH) is a rare pulmonary neoplasm. This tumour was originally thought to be a variant lesion of hemangioma. Today, however, it has been elucidated to be a tumour of epithelial origin derived from the primitive respiratory epithelium. Previous studies have reported a low Ki67 proliferation index in cases of pulmonary sclerosing hemangioma (1.4-2.2%). Moreover, the biological nature of this neoplasm, which rarely tends to metastasise to the lymph nodes, has yet to be thoroughly elucidated. A female patient in whom PSH exhibiting a high Ki-67 proliferation index was detected in the lung during follow-up for lymphoma is reported in the present study. While the Ki 67 proliferation index was 3-4% in some areas, it increased up to 15-20% in other areas. No recurrence or metastases were evident at postoperative follow-up.Publication Evaluation of prognostic factors on survival in non-small-cell lung cancer patients treated with postoperative radiotherapy(Kare Publ, 2009-01-01) Sarıhan, Süreyya; SARIHAN, SÜREYYA; Gebitekin, Cengiz; ERCAN, İLKER; GEBİTEKİN, CENGİZ; Bayram, Ahmet Sami; BAYRAM, AHMET SAMİ; EVRENSEL, TÜRKKAN; Evrensel, Turkkan; Akyıldız, Elif Ülker; AKYILDIZ, ELİF ÜLKER; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Radyasyon Onkolojisi Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Cerrahisi Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Biyoistatistik Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Onkoloji Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Patoloji Anabilim Dalı.; 0000-0003-4816-5798; 0000-0003-0684-0900; 0000-0002-2382-290X; ABB-7580-2020; AAJ-1027-2021; JCE-0097-2023; AAH-4970-2021; AAE-1069-2022OBJECTIVESTo investigate the prognostic factors on survival in non-small-cell lung cancer patients treated with postoperative radiotherapy.METHODSSixty-five patients treated with a median dose of 59 Gy (50-66.6 Gy) between October 1995 and January 2005 were included in the study. Clinical and categorical variables were analyzed.RESULTSOn multivariate analysis, presence of clinical N2 and brain metastasis at first relapse and absence of chemotherapy (p=0.02, p=0.004, p=0.004) had a negative impact on overall survival, while presence of pathological nodal involvement and absence of chemotherapy (p=0.02, p=0.04) were effective on disease-free survival. Regarding categorical variables, type of resection was found related with positive margin and N1, right-sided location with N1-e and N2, and systematic nodal dissection with N1. The number of involved lymph nodes was found related with N2 skip metastasis and involved N1-10 was related with N1-e.CONCLUSIONPresence of metastatic lymph nodes was found to be a poor prognostic factor and delivery of chemotherapy was seen to positively affect overall and disease-free survival rates.Publication An incidental unique mediastinal mass in an asymptomatic young patient: Thymolipoma(Turkish Assoc Tuberculosis & Thorax, 2013-01-01) Uğraş, Nesrin; Akyıldız, Elif Ülker; Ünal, Nermin; Bayram, Ahmet Sami; UĞRAŞ, NESRİN; AKYILDIZ, ELİF ÜLKER; Ünal, Nermin; BAYRAM, AHMET SAMİ; Uludağ Üniversitesi/Tıp Fakültesi/Patoloji Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Cerrahisi Anabilim Dalı.; 0000-0003-0684-0900; ABB-7580-2020; AAH-2716-2021; JHY-9777-2023; CDS-3138-2022Publication Immunoglobulin g4-related disease presenting as a mass in the lung(Turkish League Against Rheumatism, 2022-03-01) Akyol, Sevda; Hasdemir, Seçil; Akyıldız, Elif Ülker; AKYILDIZ, ELİF ÜLKER; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Patoloji Anabilim Dalı.Publication Immunohistochemistry for differentiation of pleural epithelioid malignant mesothelioma from adenocarcinoma: A panel for selection(Bilimsel Tıp Publishing House, 2010-12-01) Akyıldız, Elif Ülker; Öz, Buge; Aki, Hilal; Demirkaya, Ahmet; AKYILDIZ, ELİF ÜLKER; Uludağ Üniversitesi/Tıp Fakültesi/Patoloji Anabilim Dalı.; JHY-9777-2023Objective: An important difficulty pathologists confront concerning thoracic pathology is the differentiation of pleural epithelioid malignant mesothelioma from pulmonary adenocarcinoma infiltrating into the pleura or metastatic adenocarcinoma. Since epithelioid malignant mesothelioma may depict microscopic patterns similar to adenocarcinoma, morphological findings may not be sufficient to make a differential diagnosis. Up to now, many immunohistochemical markers have been proposed for their differentiation and there have been many studies on the sensitivity and specifity of each marker.Material and Method: In this study we retrospectively evaluated the reports on patients diagnosed as pleural epithelial MM and patients diagnosed as adenocarcinoma infiltrating into the pleura for the past seven years and determined the immunohistochemical markers used for differential diagnosis.Results: Most frequently used markers were calretinin and CK5/6 for epithelioid malignant mesothelioma and CEA, CD15 and TTF-1 for adenocarcinoma. EMA was used in both groups.Conclusion: We found that a panel including calretinin and CK5/6 for malignant mesothelioma and CEA and CD15 for adenocarcinoma and additionally EMA and TTF-1 avoided the difficulty in all cases. We consider that, if there is any inconsistency between the results of staining with these six markers, other antibodies should be incorporated into the panel.