Person: ASLIER, MUSTAFA
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ASLIER
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MUSTAFA
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Publication The prognostic value of thyroid gland invasion in locally advanced laryngeal cancers(Taylor, 2021-08-16) Aslıer, Mustafa; Uçurum, Bahar Ezgi; Kaya, Hilmi Cem; Coşkun, Hakan; ASLIER, MUSTAFA; UÇURUM KANTARCI, BAHAR EZGİ; KAYA, HİLMİ CEM; COŞKUN, HAMDİ HAKAN; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Kulak Burun Boğaz-Baş Boyun Cerrahisi Anabilim Dalı; 0000-0001-8257-0979; 0000-0003-0786-4453; 0000-0003-3670-4651; 0000-0002-0881-1444; ABH-1328-2021; KHB-5653-2024; GDF-8132-2022; GEH-1871-2022; DVC-7511-2022Background Locally advanced laryngeal cancers can spread to the thyroid gland by direct invasion of cricothyroid membrane. The prevalence of thyroid gland invasion (TGI) and the predictive factors of TGI were well described in literature. However, the association of TGI with survival was undetermined yet. Objectives The aim of this study is to analyze the effects of TGI on survival rates in patients with locally advanced laryngeal cancer. Materials and methods Medical records of 91 patients who underwent total laryngectomy with thyroidectomy were retrospectively reviewed. Demographical, clinical, and histopathological characteristics of the patients were noted. Kaplan-Meier test was used for survival analysis. Results Histopathology reports revealed the prevalence of TGI as 14.3% (13/91). Survival analyses showed that TGI did not affect recurrence free (p = .078) and overall (p = .080) survival rates. Conclusions Thyroid gland invasion is one of the characteristic features of locally aggressive laryngeal tumors. In this study, TGI is not a statistically significant prognostic factor that has impact on survival of the patients with locally advanced laryngeal cancer.Publication The incidence of thyroid gland invasion in advanced stage laryngeal cancers with emphasis on risk factors and its impact on survival(Elsevier, 2021-07-01) Aslıer, Mustafa; Uçurum, Bahar Ezgi; Kaya, Hilmi Cem; Coşkun, Hakan; ASLIER, MUSTAFA; KAYA, HİLMİ CEM; UÇURUM KANTARCI, BAHAR EZGİ; COŞKUN, HAMDİ HAKAN; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Kulak Burun Boğaz Hastalıkları Anabilim Dalı.; 0000-0003-3670-4651; 0000-0002-0881-1444; CCA-0193-2022; JJJ-8575-2023; GEH-1871-2022; DVC-7511-2022Publication The bibliometric aspects of case report/series in science citation index otorhinolaryngology journals(Galenos Yayıncılık, 2021-08-29) Aslıer, Nesibe Gül Yüksel; Aslıer, Mustafa; ASLIER, MUSTAFA; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Kulak Burun Boğaz Anabilim Dalı.; 0000-0001-8257-0979; KHB-5653-2024Objective: The rate of case report/series (CR/S) acceptance by the high impact journals is steadily declining mainly due to low citations. The aim of this study is primarily to investigate the bibliometric aspects of CR/S in the field of otorhinolaryngology (ORL) and secondarily to guide prospective authors as to which type of CR/S have better chances of acceptance and citation in the current publication climate.Methods: Bibliometric and citation analysis of CR/S published in Science Citation Index (SCI) journals of ORL covering the years of 2012-2016 was conducted.Results: There were 1332 (8.9%) CR/S among 14900 publications in 11 SCI ORL journals published between January 1st, 2012 and December 31st, 2016. The most common published field and subject were the 'pediatric ORL' (33.2%) and 'rare cases/conditions' (47.1%) respectively. 'General ORL' (5.13) and 'treatment' (4.93) categories had the highest citations. Only 10% of CR/S had >= 10 citations. The mean citation counts were positively correlated with impact factors of journals (r=0.131, p<0.001), mean number of authors (r=0.151, p<0.001), mean number of cases (r=0.192, p<0.001), mean number of references (r=0.315, p<0.001) and mean number of Web of Science visits (r=0.291, p<0.001).Conclusion: Although CR/S provides low citation rates in ORL SCI journals, they may serve important topics in terms of diagnosis, treatment, or complications. The findings and the main discussions of this study may direct the rationale for the consistent publication of CR/S in the evidence-based medicine era.Publication The influence of age and language on developmental trajectory of theory of mind in children with cochlear implants(Elsevier Ireland, 2020-08-01) Aslıer, Mustafa; Aslıer, Nesibe Gül Yüksel; Kırkım, Günay; Güneri, Enis Alpin; ASLIER, MUSTAFA; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Kulak Burun Boğaz Anabilim Dalı.; KHB-5653-2024Objective: The present study investigates if children with cochlear implants (CI) are associated with delayed development of Theory of Mind (ToM) and the differences in gain of ToM ability with respect to age, language and other aspects of CI.Methods: One-hundred-eleven children with participation of their hearing parents, aged between 36 months and 132 months, who had congenital profound bilateral deafness and were unilateral CI users; plus 99 healthy children underwent 'Peabody Picture Vocabulary' and 'Sally-Anne' tests. A total of 77 children with CI (mean age: 76.51 months, 31 girls and 46 boys) and 82 healthy children (mean age: 72.41 months, 47 girls and 35 boys) were included in the analyses. Analytic comparisons were created between the controls and children with CI and between subgroups of CI users by univariate and multivariate analysis. The effects of age of hearing aid use, age of CI surgery, duration of CI use, language scores and the presence of risk factors, early rehabilitation with hearing aid and CI on the ToM development were analyzed.Results: The Sally-Anne test success rates of 67.1% were significantly higher in controls than that of children with CI (49.4%) (p < 0.05). The mean age difference of the children, who were successful in Sally-Anne test was 5.33 months in favor of healthy controls. The ToM task success rates were 57.1% (24/42) and 40% (14/35) in children with early CI and late CI respectively. The children, who were good at language, were also better in Sally-Anne tests, but the mean Peabody Picture Vocabulary test scores were indifferent in the same age group with respect to the presence of CI use (p > 0.05). However, multivariate analysis presented the higher language scores as the only significant independent variable that has impact on the success in Sally-Anne test (p < 0.05).Conclusion: The results revealed that among all children, who did better in ToM were older in age and better in language skills. Children with CI also performed better in false-belief test depending on their language scores. Early CI surgery, older age, and hence longer CI use can provide a well-developed ToM for children with CI.