Person: YILMAZ, MUSTAFA SERTAÇ
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YILMAZ
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MUSTAFA SERTAÇ
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Publication The effect of histamine on acetylcholine and choline releases from the posterior hypothalamus and nucleus tractus solitarius of hypotensive rats(Wiley, 2015-09-01) Altınbaş, Burçin; Güvenç, Göken; Erkan, Leman Gizem; Yılmaz, Mustafa Sertaç; Avşar, Özge Avşar; Yalçın, Murat Yalçın; Altınbaş, Burçin; Güvenç, Göken; Erkan, Leman Gizem; YILMAZ, MUSTAFA SERTAÇ; Avşar, Özge Avşar; YALÇIN, MURAT; Uludağ Üniversitesi/Tıp Fakültesi/Fizyoloji Bölümü; 0000-0001-9496-1475; 0000-0002-5600-8162; 0000-0002-9534-736X; AAG-6956-2021; IYS-2646-2023; AAH-1571-2021; CTA-3293-2022; CNS-3398-2022; CCB-6768-2022Publication The OVLT initiates the fall in arterial pressure evoked by high dose lipopolysaccharide: Evidence that dichotomous, dose-related mechanisms mediate endotoxic hypotension(Elsevier, 2015-05-27) Feleder, Carlos; Yılmaz, M. Sertaç; Peng, Jianya; Göktalay, Gökhan; Millington, William R.; YILMAZ, MUSTAFA SERTAÇ; GÖKTALAY, GÖKHAN; Uludağ Üniversitesi/Tıp Fakültesi/Tıbbi Farmakoloji Anabilim Dalı.; 0000-0001-9496-1475; 0000-0002-2617-3626; AAH-1448-2021; AAH-1571-2021This study tested the hypothesis that lipopolysaccharide (LPS) lowers arterial pressure through two different mechanisms depending on the dose. Previously, we found that a low hypotensive dose of LPS (1 mg/kg) lowers arterial pressure by activating vagus nerve afferents. Here we report that hypotension evoked by high dose LPS (15 mg/kg) can be prevented by injecting lidocaine into the OVLT but not by vagotomy or inactivation of the NTS. The hypotension produced by both LPS doses was correlated with elevated extracellular norepinephrine concentrations in the POA and prevented by blocking alpha-adrenergic receptors. Thus, initiation of endotoxic hypotension is dose-related, mechanistically. (C) 2015 Elsevier B.V. All rights reserved.Publication Central histaminergic system mediates prostaglandin cascade induced cardiovascular effects(Federation Amer, 2013-04-01) Yalçın, Murat; Altınbaş, Burçin; Topuz, Bora Burak; Yılmaz, Mustafa Sertaç; Savcı, Vahide; Aydın, Sami; YALÇIN, MURAT; Altınbaş, Burçin; Topuz, Bora Burak; YILMAZ, MUSTAFA SERTAÇ; SAVCI, VAHİDE; Aydın, Sami; Uludağ Üniversitesi/Fen-Edebiyat Fakültesi/Fizik Bölümü; 0000-0002-5600-8162; 0000-0001-9496-1475; AAG-6956-2021; IYS-2646-2023; KHD-9454-2024; AAH-1571-2021; EBJ-3864-2022; CCT-7508-2022Publication CDP-choline protects against sepsis-induced acute tissue injury in rats(Federation Amer, 2013-04-01) Yılmaz, Mustafa Sertaç; Sevim, Çiğdem; Altınbaş, Burçin; Özyiğit, Musa Özgür; Savcı, Vahide; Yalçın, Murat; YILMAZ, MUSTAFA SERTAÇ; Sevim, Çiğdem; Altınbaş, Burçin; ÖZYİĞİT, MUSA ÖZGÜR; SAVCI, VAHİDE; YALÇIN, MURAT; Uludağ Üniversitesi/Veteriner Fakültesi/Fizyoloji Bölümü; Uludağ Üniversitesi/Veteriner Fakültesi/Patholoji Bölümü; 0000-0001-9496-1475; 0000-0002-5600-8162; 0000-0002-9534-736X; 0000-0002-0575-3090; AAG-6956-2021; IYS-2646-2023; AAH-2873-2021; AAH-1571-2021; AAR-6478-2021; KHD-9454-2024; JED-7015-2023Publication Blockade of a-adrenergic receptors in the preoptic area/anterior hypothalamus prevents lipopolysaccharide evoked hypotension(Federation Amer Soc Exp Biol, 2008-04-01) Myer, Brian S.; Feleder, Carlos; Millington, William R.; Yılmaz, Mustafa Sertaç; YILMAZ, MUSTAFA SERTAÇ; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Kalp ve Damar Cerrahisi Anabilim Dalı.; 0000-0001-9496-1475; AAH-1571-2021