Person: DOĞAN, ŞEREF
Loading...
Email Address
Birth Date
Research Projects
Organizational Units
Job Title
Last Name
DOĞAN
First Name
ŞEREF
Name
6 results
Search Results
Now showing 1 - 6 of 6
Publication Mr imaging in the detection of diffuse axonal injury with mild traumatic brain injury(Maney Publishing, 2008-11-01) Topal, Naile Bolca; Hakyemez, Bahattin; Erdoğan, Cüneyt; Bulut, Mehtap; Köksal, Özlem; Akköse, Şule; Doğan, Şeref; Parlak, Müfit; Özgüç, Halil; Korfalı, Ender; BOLCA TOPAL, NAİLE; HAKYEMEZ, BAHATTİN; Erdoğan, Cüneyt; Bulut, Mehtap; KÖKSAL, ÖZLEM; Akköse, Şule; DOĞAN, ŞEREF; PARLAK, MÜFİT; Özgüç, Halil; Korfalı, Ender; Tıp Fakültesi; Acil Tıp Ana Bilim Dalı; 0000-0002-3425-0740; 0000-0003-2271-5659; AAI-2327-2021; AAI-2318-2021; COE-1124-2022; AAX-5571-2021; AAK-8332-2020; JRG-1971-2023; AAI-6531-2021; AAG-8521-2021; FUL-4254-2022; FDB-4085-2022Purpose: To evaluate the occurrence and distribution of mild traumatic brain injury MTBI) caused by diffuse axonal injury DAI) using magnetic resonance MR) imaging and to attempt to correlate MR findings with post-concussion symptoms PCS).Patients and methods: Forty MTBI patients mean age: 32.5 years) with normal cranial computed tomography CT) findings were examined with standard MR protocol including T1-weighted, T(2)-weighted, fluid attenuated inversion recovery FLAIR), gradient echo GRE) and diffusion-weighted DW) sequences. MR imaging was performed within 24 hours of injury. The lesions were classified as DAI based on their location and morphologic appearance.Results: In MR imaging of five 12.5%) of the patients, the lesions compatible with DAI were observed. Four patients 10%) had the foci of low signal intensity compatible with hemorrhagic shear injury on the GRE sequence, and five 12.5%) patients had high signal intensity on FLAIR and DW sequence.Conclusion: MR imaging can be helpful in revealing DAI lesions in patients with normal CT scan findings after MTBI. FLAIR, GRE and DW sequences are superior to conventional spin-echo images in detecting DAI lesions. [Neurol Res 2008; 30: 974-978]Publication Posterior transdural discectomy for thoracic disc herniation(Turkish Neurosurgical Soc, 2023-01-01) Doğan, Şeref; Taşkapılıoğlu, Mevlüt Özgür; Eser, Pınar; Balçın, Rabia Nur; DOĞAN, ŞEREF; TAŞKAPILIOĞLU, MEVLÜT ÖZGÜR; Eser, Pınar; BALÇIN, RABİA NUR; Tıp Fakültesi; Beyin Cerrahi Ana Bilim Dalı; 0000-0003-0132-9927; AAI-2073-2021; GXV-3107-2022; AAI-6531-2021; IRO-2619-2023AIM: To evaluate the safety and efficacy of posterior transdural discectomy for thoracic disc herniation. MATERIAL and METHODS: The medical records of seven patients who underwent posterior transdural discectomy for thoracic disc herniation were retrospectively evaluated. RESULTS: Between 2012 and 2020, seven patients (five men and two women) who were aged between 17 and 74 years underwent posterior transdural discectomy. Numbness is the most common presenting symptom, and two patients complained of urinary incontinence. T10-11 was the most affected level. All patients underwent at least 6 months of follow-up. There were no postoperative cerebrospinal fluid leaks and neurological complications postoperatively. All patients maintained their baseline neurological status or improved after surgery. No patient had secondary neurological deterioration or need for further surgical treatment. CONCLUSION: The posterior transdural approach is a safe procedure that should be considered in lateral and paracentral thoracic disc herniations providing a more direct surgical intervention.Publication Statistical shape analyses of pediatric patients with scoliosis after surgical correction(Turkish Neurosurgical Soc, 2023-01-01) Ocakoğlu, Gökhan; Taşkapılıoğlu, Mevlüt Özgür; Kaya, İsmail Seçkin; Akesen, Burak; Doğan, Şeref; OCAKOĞLU, GÖKHAN; TAŞKAPILIOĞLU, MEVLÜT ÖZGÜR; KAYA, İSMAİL SEÇKİN; AKESEN, BURAK; DOĞAN, ŞEREF; Tıp Fakültesi; Biyoistatistik Ana Bilim Dalı; 0000-0002-1114-6051; HLG-6346-2023; IRO-2619-2023; ILC-4543-2023; AAH-9833-2021; AAI-6531-2021AIM: To investigate the preoperative and postoperative differences in the upper-body and spinal shapes of patients with scoliosis. MATERIAL and METHODS: Digitized two-dimensional X-ray images were used to obtain the shapes of the upper-body and spine. The preoperative and postoperative mean shapes were compared by using a Generalized Procrustes analysis. The thin plate spline (TPS) method was used to evaluate the spinal shape deformation between the preoperative and postoperative periods.RESULTS: The pre-and postoperative upper-body and spinal shape differences were significant. The TPS graphics showed high-level deformations between the pre-and postoperative periods. The left superior border of the L4 spinous process showed the highest deformation.CONCLUSION: The preoperative and postoperative upper-body and spinal shape differences and structural deformations that correlated with scoliosis were shown to be significant.Publication Effects of systemic and local interferon beta- 1a on epidural fibrosis(Korean Soc Spine Surgery, 2016-06-01) Taskapılıoğlu, Mevlüt Özgür; TAŞKAPILIOĞLU, MEVLÜT ÖZGÜR; Doğan, Seref; DOĞAN, ŞEREF; Işık, Semra; Ocakoğlu, Gökhan; OCAKOĞLU, GÖKHAN; Özgün, Gonca; Ugraş, Nesrin; UĞRAŞ, NESRİN; Tıp Fakültesi; Nöroşurji Ana Bilim Dalı; 0000-0001-5472-9065; 0000-0002-6929-7135; 0000-0002-1114-6051; AAH-5180-2021; AAW-5254-2020; ABB-8161-2020; HLG-6346-2023; AAH-2716-2021; K-6580-2015; AAI-6531-2021; KGL-6139-2024Study Design: Level 1 randomized controlled study.Purpose: To investigate the effects of systemic and local interferon-beta-1a (IFN-beta-1a) on prevention of epidural fibrosis using histopathological parameters.Overview of Literature: Epidural fibrosis involves fibroblastic invasion of nerve roots into the epidural space. Formation of dense fibrous tissue causes lumbar and radicular pain. Many surgical techniques and several materials have been proposed in the literature, but no study has assessed the effect of IFN-beta-1a on prevention of epidural fibrosis.Methods: Forty-eight adult female Sprague-Dawley rats were divided into six groups of eight: sham group, control group, systemic 44 mu g IFN-beta-1a group and 22 mu g IFN-beta-1a group (after laminectomy and discectomy, 0.28 mL and 0.14 mL IFN-beta-1a applied subcutaneously three times for a week, respectively), local 44 mu g IFN-beta-1a group (laminectomy and discectomy, followed by 0.28 mL IFN-beta-1a on the surgical area), and local 22 mu g IFN-beta-1a group (laminectomy and discectomy, followed by 0.14 mL IFN-beta-1a on the surgical area). All rats were sacrificed after 4 weeks and groups were evaluated histopathologically.Results: Compared with sham and control groups, significantly less epidural fibrosis, dural adhesion, and fibroblast cell density were observed in the local and systemic 44 mu g IFN-beta-1a groups. No other differences were evident between the local and systemic groups.Conclusions: IFN-beta-1a is effective in preventing epidural fibrosis with systemic and local application.Publication Leptomeningeal pneumocephalus and pneumorrhachis: Signs of pneumothorax in case of syringopleural shunting(Elsevier, 2021-09-11) Tonkaz, Mehmet; Özpar, Rıfat; Erkal, Duygu; Doğan, Şeref; Bayram, Ahmet Sami; Gökce, Serhat; Hakyemez, Bahattin; TONKAZ, MEHMET; ÖZPAR, RİFAT; ERKAL TONKAZ, DUYGU; DOĞAN, ŞEREF; BAYRAM, AHMET SAMİ; GÖKÇE, SERHAT; HAKYEMEZ, BAHATTİN; Tıp Fakültesi; Göğüs Cerrahisi Ana Bilim Dalı; 0000-0001-6649-9287; 0000-0002-8201-1568; 0000-0003-0684-0900; DZJ-5260-2022; AAH-5062-2021; EUK-9600-2022; AAI-6531-2021; ABB-7580-2020; CSN-2488-2022; AAI-2318-2021In this article, we present a case of leptomeningeal pneumocephalus and pneumorrhachis secondary to pneumothorax that occurred six years after syringopleural shunting.Publication Treatment strategies for unknown anatomic pathology ventriculus terminalis case series: single center experience(Bursa Uludağ Üniversitesi, 2024-08-06) Özmarasalı, Ali İmran; Yağubov, Fakhraddin; Eser, Pınar; Doğan, Şeref; YAGUBOV, FAKHRADDIN; Eser, Pınar; DOĞAN, ŞEREFThe ventriculus terminalis is a cavity in the conus medullaris, bounded by ependymal cells, associated with the central canal. It is an anatomical structure that is very rare in adults, with a limited number of surgical cases that have been reported in the literature. In children, it is regarded as a normal congenital variation, known to regress before five years of age, and very few symptomatic cases have been reported in both pediatric and adult populations. It is often asymptomatic in adults and is detected incidentally. Although potentially nonsignificant individually, symptoms can range from nonspecific low back pain to sphincter dysfunction and focal neurologic deficits. Our purpose is to discuss our management strategy in comparison to the existing literature. A retrospective review was conducted of all adult patients (aged 17 years and older) diagnosed with ventriculus terminalis who were referred to the hospital between 2010 and 2020. Clinical classification was made according to the classification defined by Batista. In addition, Ganau's classification was also used. Five patients were included in the study. The majority of these patients (n=4, 80%) were symptomatic at the time of diagnosis, with nonspecific back pain being the most common symptom (n=3, (60%). None of the patients required neurosurgical intervention during the follow-up period of 21.6±8.9 months, as there was no clinical deterioration observed. Ventriculus terminalis is a rare pathology that may develop de novo in adults, often remaining undiagnosed until the cyst enlarges, and can manifest with a wide spectrum of symptoms. When identified, it requires careful management, involving surgery when necessary and a conservative approach when appropriate.