Person: ÖZDEMİR, BÜLENT
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ÖZDEMİR
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BÜLENT
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Publication Association between blood pressure, inflammation and spirometry parameters in chronic obstructive pulmonary disease(Korean Assoc Internal Medicine, 2019-01-01) Arslan, Sülhattin; Yıldız, Gürsel; Özdemir, Levent; Kaysoydu, Erdal; Özdemir, Bülent; ÖZDEMİR, BÜLENT; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Kardiyoloji Anabilim Dalı.; JHE-3353-2023Background/Aims: Many systems including the cardiovascular system (ischemic heart diseases, heart failure, and hypertension) may act as comorbidities that can be seen during the course of chronic obstructive pulmonary disease (COPD). Comorbidities affect the severity and prognosis of COPD negatively. Nearly 25% of patients with COPD die due to cardiovascular diseases. In this study, we aimed to evaluate the relationship between the blood pressure, inflammation, hypoxia, hypercapnia, and the severity of airway obstruction.Methods: We included 75 COPD patients in the study with 45 control cases. We evaluated age, sex, body mass index, smoking history, C-reactive protein levels, 24-hour ambulatory blood pressure Holter monitoring, arterial blood gas, and respiratory function tests of the patient and the control groups.Results: In COPD patients, the night time systolic, diastolic blood pressures and pulse per minute and the mean blood pressures readings were significantly elevated compared to the control group (p < 0.05). In the correlation analysis, night time systolic pressure was associated with all the parameters except forced expiratory volume in 1 second (FEV1%). Diastolic blood pressure was associated with pH and HCO3 levels. The mean night time, day time pulse pressures and 24-hour pulse per minute values were also associated with all the parameters except FEV1%.Conclusions: In this study we found that parameters of systolic and diastolic blood pressures and pulse pressures were significantly elevated in COPD patients compared to the control groups. Blood pressure was associated blood gas parameters and inflammation parameters in COPD patients. This, in turn, may cause understanding of the pathophysiology of COPD and its complications.Publication The relationship between Cardiotrophin-1 and Troponin-I in coronary arterial bypass grafting on the beating heart: A prospective study(Forum Multimedia Publishing, 2015-08-01) Çalışkan, Serhat; Beşli, Feyzullah; Yıldırım, Ahmet; Güngören, Fatih; Alışır, Mehmet Fethi; Polat, Ufuk; Özdemir, Bülent; Biçer, Murat; Çalışkan, Serhat; Yıldırım, Ahmet; Güngören, Fatih; Polat, Ufuk; ÖZDEMİR, BÜLENT; BİÇER, MURAT; Uludağ Üniversitesi/Tıp Fakültesi/Kardiyoloji Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Kalp Damar Cerrahisi Anabilim Dalı.; 0000-0003-4411-8185; 0000-0002-0815-9505; AAA-3163-2021; ABC-2231-2020; AAC-9352-2021; ERK-8925-2022; JTI-0902-2023; DLY-6718-2022Objective: Cardiotrophin-1 (CT-1) is closely associated with many cardiovascular diseases, such as hypertension, myocardial infarction (MI), and heart failure, and exhibits a cardioprotective effect in ischemia-reperfusion injury. The aim of this study was to evaluate the relationship between CT-1 and Troponin-I (Tn-I) in off-pump coronary artery bypass (OPCAB) grafting on the beating heart.Methods: Seventy-eight patients (mean age 60.8 +/- 9.7 years, 79.5% male) undergoing elective OPCAB surgery were included in this study undertaken between July 1, 2012 and July 1, 2013 in the Department of Cardiology and Cardiac Surgery, University School of Medicine Hospital. Venous blood samples were collected 5 minutes before OPCAB surgery and 6 hours after surgery. Plasma CT-1 levels were measured using the ELISA method.Results: Compared to the preoperative period, Tn-I and CT-1 values were higher in the postoperative period [0.255 ng/mL (0.030-0.430) versus 0.045 ng/mL (0.005-0.090), P < .001; and 33.7 pg/mL (15.8-98.5) versus 8.7 pg/mL (0.68-25.4), P <. 001]. There was also an elevation in white blood cells, aspartate aminotransferase, creatine kinase (CK), and creatine kinase MB (CK-MB) values, as well as a decrease in hemoglobin values (P < .001). When a correlation analysis for postoperative CT-1 was performed, there was a significant positive correlation between postoperative CK, CK-MB, and Tn-I levels (r = 0.250, P < .027; r = 0.270, P =.017; and r = 0.241, P < .034).Conclusion: CT-1 was found to be associated with Tn-I, which is used to detect myocardial damage after OPCAB surgery. CT-1 may also be used to detect myocardial damage.Publication Association of aortic diameters with coronary artery disease severity and albumin excretion(Hindawi, 2015-04-08) Özdemir, Bülent; Emul, Ali; Özdemir, Levent; Sağ, Saim; Biçer, Murat; Aydınlar, Ali; ÖZDEMİR, BÜLENT; Sağ, Saim; BİÇER, MURAT; AYDINLAR, ALİ; Uludağ Üniversitesi/Tıp Fakültesi/Kardiyoloji Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Kalp, Damar Cerrahisi Anabilim Dalı.; 0000-0002-8974-8837; 0000-0001-8404-8252; AAW-9185-2020; ABC-2231-2020; AAI-6632-2021; JHE-3353-2023Introduction. Aortic diameters, aortic distensibility, microalbuminuria, coronary artery disease which are all together related to vascular aging are investigated in this paper. Methods. Eighty consecutive nondiabetic patients undergoing elective coronary angiography were enrolled into the study. Systolic and diastolic aortic diameters, aortic distensibility, CAD severity by angiogram with the use of Gensini scoring, and albumin excretion rates were determined. Results. Cases with CAD had significantly larger systolic (30,72 +/- 3,21mm versus 34,19 +/- 4,03 mm for cases without and with CAD, resp.) and diastolic aortic diameters measured 3 cm above aortic valve compared to patients without CAD (33,56 +/- 4,07 mm versus 29,75 +/- 3,12 mm). The systolic and diastolic diameters were significantly higher in albuminuria positive patients compared to albuminuria negative patients (p = 0.017 and 0.008, resp., for systolic and diastolic diameters). Conclusion. In conclusion aortic diameters are increased in patients with coronary artery disease and in patients with microalbuminuria. In CAD patients, systolic blood pressure, pulse pressure, aortic systolic and diastolic pressure, and albumin excretion rate were higher and aortic distensibility was lower.Publication Attitudes of smoking and knowledge about substances in cigarette smoke in university students(Scibulcom, 2015-01-01) Özdemir, A.; Utkualp, N.; Özdemir, B.; Özdemir, L.; ÖZDEMİR, AYSEL; UTKUALP, NEVİN; ÖZDEMİR, BÜLENT; ÖZDEMİR, LEVENT; Uludağ Üniversitesi/Sağlık Bilimleri Fakültesi/Halk Sağlığı Hemşireliği Bölümü.; Uludağ Üniversitesi/Tıp Fakültesi/Kardiyoloji Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Halk Sağlığı Anabilim Dalı.; 0000-0002-0815-9505; 0000-0002-4330-8334; AAJ-1202-2021; C-7487-2018; AAC-9352-2021; FRF-3343-2022Smoking is a worldwide problem causing significant mortality. Due to the complications occurring later in life giving up is not intended for many users. Media, environment, family, friends, and cultural factors are effective in the onset and prolongation of this habit.In this study we aimed to determine the knowledge level of 188 students of the Institute of Health Sciences who gave informed consent and participated in the study. We gathered data with a questionnaire form and asked questions related to the diseases proven to be caused by smoking and the substances in the cigarette smoke. We used the Fagerstrom Nicotine Dependence Test to evaluate the nicotine dependence status of smoking students. The mean age of the students was 20.49 +/- 1.19 and the number of females was 144 (76.6%). The mean age of onset of smoking and alcohol consumption was 17.04 +/- 2.13 and 17.06 +/- 2.34, respectively. Overall rate of smoking was 11.7% (n = 22) and in females and males 7.6 and 25.0%, respectively (p < 0.003).It was concluded that the smoking rate in students of the Institute of Health Sciences is high, particularly in male students. The knowledge of substances in cigarette smoke did not affect the smoking pattern of students.Publication Association of epicardial adipose tissue thickness by echocardiography and heart rate recovery in metabolic syndrome(Elsevier, 2013-10-29) Böyük, Ferit; Özdemir, Bülent; Sağ, Saim; Şentürk, Tunay; Kaderli, Aysel Aydın; Güllülü, Sümeyye; Aydınlar, Ali; Böyük, Ferit; ÖZDEMİR, BÜLENT; Sağ, Saim; ŞENTÜRK, TUNAY; Kaderli, Aysel Aydın; GÜLLÜLÜ, NAZMİYE SÜMEYYE; AYDINLAR, ALİ; Uludağ Üniversitesi/Tıp Fakültesi/Kardiyoloji Bölümü; C-1517-2017; AAI-6632-2021; AAW-9185-2020; JIX-2728-2023; JHE-3353-2023; CXL-7581-2022; JGR-6552-2023Publication Serum fetuin-a levels for the detection and evaluation of the left ventricular systolic heart failure(Elsevier, 2013-10-29) Keçebaş, Mesut; Güllülü, Sümeyye; Sağ, Saim; Açıkgöz, Ebru; Besli, Feyzullah; Şentürk, Tunay; Kaderli, Aysel Aydın; Özdemir, Bülent; Baran, İbrahim; Sarandöl, Emre; Aydınlar, Ali; Keçebaş, Mesut; GÜLLÜLÜ, NAZMİYE SÜMEYYE; Sağ, Saim; Açıkgöz, Ebru; Besli, Feyzullah; ŞENTÜRK, TUNAY; Kaderli, Aysel Aydın; ÖZDEMİR, BÜLENT; Baran, İbrahim; SARANDÖL, EMRE; AYDINLAR, ALİ; Uludağ Üniversitesi/Tıp Fakültesi/Kardiyoloji Anabilim Dalı; Uludağ Üniversitesi/Tıp Fakültesi/Biyokimya Anabilim Dalı; 0000-0002-6206-8700; C-1517-2017; ABE-1716-2020; AAW-9185-2020; AAI-6632-2021; JKQ-3658-2023; JGR-6552-2023; CBS-6076-2022; DXE-4816-2022; CXL-7581-2022; JHE-3353-2023; CDA-1396-2022Publication Coronary risk factors and coronary angiography results of 12.257 patients(Elsevier, 2013-10-29) Günay, Şeyda; Serdar, Osman Akın; Özyılmaz, Sinem Özbay; Dereli, Seçkin; Aydınlar, Ali; Baran, İbrahim; Özdemir, Bülent; Yeşilbursa, Dilek; Güllülü, Sümeyye; GÜNAY POLATKAN, ŞEYDA; SERDAR, OSMAN AKIN; Özyılmaz, Sinem Özbay; Dereli, Seçkin; AYDINLAR, ALİ; Baran, İbrahim; ÖZDEMİR, BÜLENT; YEŞİLBURSA, DİLEK; GÜLLÜLÜ, NAZMİYE SÜMEYYE; Uludağ Üniversitesi/Tıp Fakültesi/Kardiyoloji Anabilim Dalı; 0000-0003-1744-8883; 0000-0002-7788-9739; 0000-0003-0090-3835; AAF-5116-2019; AAG-8709-2020; AAI-5350-2021; AAI-6632-2021; AAJ-3962-2020; AAB-5861-2021; CDA-1396-2022; JHE-3353-2023; EHA-0046-2022; JGR-6552-2023