Prognostic value of pretreatment tumor-to-blood Standardized Uptake Ratio (SUR) in rectal cancer
dc.contributor.author | Kandemirli, Sedat Giray | |
dc.contributor.buuauthor | Belge, Gökçe | |
dc.contributor.buuauthor | Bilgin, Cem | |
dc.contributor.buuauthor | Özkaya, Güven | |
dc.contributor.buuauthor | Alper, Eray | |
dc.contributor.department | Uludağ Üniversitesi/Tıp Fakültesi/Radyoloji Bölümü | tr_TR |
dc.contributor.department | Uludağ Üniversitesi/Tıp Fakültesi/Nükleer Tıp Bölümü | tr_TR |
dc.contributor.department | Uludağ Üniversitesi/Tıp Fakültesi/Biyoistatistik Bölümü | tr_TR |
dc.contributor.orcid | 0000-0003-0297-846X | |
dc.contributor.researcherid | CFT-6124-2022 | |
dc.contributor.researcherid | A-4421-2016 | |
dc.contributor.researcherid | EJU-2547-2022 | |
dc.contributor.scopusid | 57216409186 | |
dc.contributor.scopusid | 57200617643 | |
dc.contributor.scopusid | 16316866500 | |
dc.contributor.scopusid | 7006827670 | |
dc.date.accessioned | 2024-05-13T13:23:46Z | |
dc.date.available | 2024-05-13T13:23:46Z | |
dc.date.issued | 2020-06 | |
dc.description.abstract | Objectives: The prognostic value of SUV on pretreatment F-18 FDG PET/CT imaging in patients with rectal cancer is a matter of debate. SUR is of prognostic value for survival in different cancers. In this study, we aimed to examine the potential prognostic value of SUR and other parameters in pretreatment F-18 FDG PET/CT for non-metastatic rectal cancer. Methods: One hundred four non-metastatic rectal cancer patients who underwent pretreatment PET/CT between March 2012 and January 2018 were included in the study. Firstly, SUVmax, SUVmean, MTV, and TLG were calculated semi-automatically at the workstation. SUR was calculated as the ratio of tumor SUVmax to thoracic aorta blood SUVmean. Univariate Cox regression and Kaplan–Meier analysis were used to evaluate overall survival (OS), progression free survival (PFS), and local recurrence (LR). Then, multivariate Cox regression analysis, which included the parameters that were significant in the univariate analysis, was performed. Results: Multivariate Cox regression analysis revealed that SUR was a prognostic factor for PFS. Age and T stage were prognostic factors for both OS and PFS. MTV was found to be independent risk factors for OS. Conclusions: In our study, SUR was the only F-18 FDG PET/CT parameter found to be significant for PFS. The development of new parameters can increase the prognostic value of F-18 FDG PET/CT. | en_US |
dc.identifier.citation | Belge, G. vd. (2020). Prognostic value of pretreatment tumor-to-blood Standardized Uptake Ratio (SUR) in rectal cancer". Annals of nuclear medicine, 34(6), 432-440 | en_US |
dc.identifier.doi | https://doi.org/10.1007/s12149-020-01465-8 | |
dc.identifier.endpage | 440 | |
dc.identifier.issn | 0914-7187 | |
dc.identifier.issue | 6 | |
dc.identifier.pubmed | 32297136 | |
dc.identifier.scopus | 2-s2.0-85083445957 | |
dc.identifier.startpage | 432 | |
dc.identifier.uri | https://link.springer.com/article/10.1007/s12149-020-01465-8 | |
dc.identifier.uri | https://hdl.handle.net/11452/41425 | |
dc.identifier.volume | 34 | tr_TR |
dc.identifier.wos | 000526293600001 | tr_TR |
dc.indexed.pubmed | PubMed | en_US |
dc.indexed.scopus | Scopus | en_US |
dc.language.iso | en | en_US |
dc.publisher | Springer | en_US |
dc.relation.collaboration | Yurt dışı | tr_TR |
dc.relation.collaboration | Yurt içi | tr_TR |
dc.relation.journal | Annals of Nuclear Medicine | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi | tr_TR |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Fluorodeoxyglucose f18 | en_US |
dc.subject | Positron-emission tomography | en_US |
dc.subject | Prognosis | en_US |
dc.subject | Rectal cancer | en_US |
dc.subject | Sur | en_US |
dc.subject | Survival | en_US |
dc.subject | Positron-emission-tomography | en_US |
dc.subject | Brain transfer constants | en_US |
dc.subject | Cell lung-canger | en_US |
dc.subject | Colorectal-cancer | en_US |
dc.subject | F-18-fdg pet | en_US |
dc.subject | Fdg-pet/ct | en_US |
dc.subject | Volumetric parameters | en_US |
dc.subject | Graphical evaluation | en_US |
dc.subject | Renal-failure | en_US |
dc.subject | Survival | en_US |
dc.subject.emtree | Capecitabine | en_US |
dc.subject.emtree | Capecitabine plus oxaliplatin | en_US |
dc.subject.emtree | Fluorodeoxyglucose f 18 | en_US |
dc.subject.emtree | Fluoropyrimidine | en_US |
dc.subject.emtree | Fluorouracil | en_US |
dc.subject.emtree | Folinic acid | en_US |
dc.subject.emtree | Oxaliplatin | en_US |
dc.subject.emtree | Fluorodeoxyglucose f 18 | en_US |
dc.subject.emtree | Adult | en_US |
dc.subject.emtree | Age | en_US |
dc.subject.emtree | Article | en_US |
dc.subject.emtree | Cancer prognosis | en_US |
dc.subject.emtree | Cancer recurrence | en_US |
dc.subject.emtree | Cancer staging | en_US |
dc.subject.emtree | Cancer survival | en_US |
dc.subject.emtree | Female | en_US |
dc.subject.emtree | Glycolysis | en_US |
dc.subject.emtree | Human | en_US |
dc.subject.emtree | Major clinical study | en_US |
dc.subject.emtree | Male | en_US |
dc.subject.emtree | Maximum standardized uptake value | en_US |
dc.subject.emtree | Mean standardized uptake value | en_US |
dc.subject.emtree | Metabolic tumor volume | en_US |
dc.subject.emtree | Middle aged | en_US |
dc.subject.emtree | Overall survival | en_US |
dc.subject.emtree | Positron emission tomography-computed tomography | en_US |
dc.subject.emtree | Priority journal | en_US |
dc.subject.emtree | Progression free survival | en_US |
dc.subject.emtree | Rectum cancer | en_US |
dc.subject.emtree | Rectum carcinoma | en_US |
dc.subject.emtree | Risk factor | en_US |
dc.subject.emtree | Standardized uptake value ratio | en_US |
dc.subject.emtree | Survival analysis | en_US |
dc.subject.emtree | Thoracic aorta | en_US |
dc.subject.emtree | Blood | en_US |
dc.subject.emtree | Disease free survival | en_US |
dc.subject.emtree | Metabolism | en_US |
dc.subject.emtree | Pathology | en_US |
dc.subject.emtree | Rectum tumor | en_US |
dc.subject.emtree | Recurrent disease | en_US |
dc.subject.emtree | Standard | en_US |
dc.subject.emtree | Transport at the cellular level | en_US |
dc.subject.mesh | Biological transport | en_US |
dc.subject.mesh | Disease-free survival | en_US |
dc.subject.mesh | Female | en_US |
dc.subject.mesh | Fluorodeoxyglucose f18 | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Male | en_US |
dc.subject.mesh | Middle aged | en_US |
dc.subject.mesh | Positron emission tomography computed tomography | en_US |
dc.subject.mesh | Rectal neoplasms | en_US |
dc.subject.mesh | Recurrence | en_US |
dc.subject.mesh | Reference standards | en_US |
dc.subject.scopus | Fluorodeoxyglucose F 18; Tumor Burden; Dice | en_US |
dc.subject.wos | Radiology | en_US |
dc.subject.wos | Nuclear medicine & Medical imaging | en_US |
dc.title | Prognostic value of pretreatment tumor-to-blood Standardized Uptake Ratio (SUR) in rectal cancer | en_US |
dc.type | Article | en_US |
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