Covid-19 hastalarının tedavisinde moleküler hidrojen inhalasyonunun potansiyel uygulaması
Date
2022-07-02
Journal Title
Journal ISSN
Volume Title
Publisher
Bursa Uludağ Üniversitesi
Abstract
COVID-19 (Corona Virüs Hastalığı 2019), SARS-CoV-2 (Şiddetli akut solunum yolu sendromu koronavirüs 2) suşunun yol açtığı akut solunum sendromu hastalığıdır. İlk COVID-19 vakası Aralık 2019'da ortaya çıkmış ve aylar içinde tüm dünyada görülen salgın haline gelmiştir. Moleküler hidrojen (H₂); reaktif oksijen türlerini seçici olarak süpürmesi, inflamatuar sitokinlerin inaktivasyonu, antiapoptotik özelliği sayesinde birçok hastalık üzerinde etkili bir tedavi yöntemi olarak kullanılmaktadır. Özellikle inflamatuar akciğer hasarı tedavisinde H₂'nin terapötik etkileri, COVID-19 hastalığını hafifletebileceği görüşünü desteklemektedir. Aynı zamanda, H₂ SARS-CoV-2'nin neden olduğu yıkıcı sitokin fırtınasını ve akciğer hasarını azaltabilir. Bu nedenle moleküler hidrojen tedavisi, COVID-19 için yeni ve etkili bir yardımcı tedavi yöntemi olma potansiyeline sahiptir. Fakat bu hipotezin doğrulanması için daha fazla klinik denemelere ihtiyaç vardır.
COVID-19 (Corona Virus Disease 2019) is an acute respiratory syndrome disease caused by the SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2) strain. The first case of COVID-19 appeared in December 2019 and within several months it became a worldwide epidemic. Molecular hydrogen (H₂) was used as an effective treatment method for many diseases thanks to its selective scavenging of reactive oxygen species, inactivation of inflammatory cytokines, and anti-apoptotic properties. The therapeutic effects of H₂, especially in the treatment of inflammatory lung injuries, support the point of view that it can alleviate COVID-19 disease. At the same time, H₂ can reduce the devastating cytokine storm and lung damage caused by SARS-CoV-2. Therefore, molecular hydrogen therapy has the potential to be a new and effective adjunctive therapy for COVID-19. However, further clinical trials are needed to confirm this hypothesis.
COVID-19 (Corona Virus Disease 2019) is an acute respiratory syndrome disease caused by the SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2) strain. The first case of COVID-19 appeared in December 2019 and within several months it became a worldwide epidemic. Molecular hydrogen (H₂) was used as an effective treatment method for many diseases thanks to its selective scavenging of reactive oxygen species, inactivation of inflammatory cytokines, and anti-apoptotic properties. The therapeutic effects of H₂, especially in the treatment of inflammatory lung injuries, support the point of view that it can alleviate COVID-19 disease. At the same time, H₂ can reduce the devastating cytokine storm and lung damage caused by SARS-CoV-2. Therefore, molecular hydrogen therapy has the potential to be a new and effective adjunctive therapy for COVID-19. However, further clinical trials are needed to confirm this hypothesis.
Description
Keywords
COVID-19, Moleküler hidrojen, SARS-CoV-2, Sitokin fırtınası, Molecular hydrogen, Cytokine storm
Citation
Alwazeer, D. vd. (2022). "Covid-19 hastalarının tedavisinde moleküler hidrojen inhalasyonunun potansiyel uygulaması". Uluslararası Biyosistem Mühendisliği Dergisi, 3(1), 58-66.