Lornoxicam injection is inferior to betamethasone in the treatment of subacromial impingement syndrome: A prospective randomized study of functional outcomes
dc.contributor.author | Aksakal, Murat | |
dc.contributor.author | Ermutlu, Cenk | |
dc.contributor.author | Özkan, Yüksel | |
dc.contributor.buuauthor | Özkaya, Güven | |
dc.contributor.department | Uludağ Üniversitesi/Tıp Fakültesi/İstatistik Anabilim Dalı. | tr_TR |
dc.contributor.orcid | 0000-0003-0297-846X | tr_TR |
dc.contributor.researcherid | A-4421-2016 | tr_TR |
dc.contributor.scopusid | 16316866500 | tr_TR |
dc.date.accessioned | 2023-02-23T07:40:46Z | |
dc.date.available | 2023-02-23T07:40:46Z | |
dc.date.issued | 2017-02 | |
dc.description.abstract | Subacromial impingement syndrome (SIS) is one of the most frequent shoulder pathologies. Initial treatment is conservative. Subacromial injection of drugs achieves a high concentration at the pathologic site with less drug use and fewer systemic side effects. Glucocorticoids are most frequently injected. One concern with steroid use is the wide array of potential systemic and local complications. Nonsteroidal anti-inflammatory drugs (NSAIDs) are also peripherally acting and can be used locally. Although intraarticular (IA) use of NSAIDs is common in orthopedic practice, it is mostly restricted to the knee joint. Reports of local NSAID for joint pathologies are relatively rare. This study compared the efficacy of single-dose subacromial injections of betamethasone and lornoxicam for treatment of SIS. Subacromial injections of either 7.0 mg betamethasone or 8 mg lornoxicam were received by 70 patients with mean age 53 (46-68) years. Treatment outcome was assessed with Constant-Murley and UCLA questionnaires before injection and at 2aEuro, 4aEuro, and 6aEuroweek follow-ups. The change in outcome scores compared to pretreatment was higher in the steroid group at all follow-ups (p < 0.001). Patients in the steroid group showed a significant improvement at all follow-ups compared to pretreatment (p < 0.001) and previous follow-ups (p < 0.05) at all times. Patients in the lornoxicam group showed a significant functional improvement in week 2 (p < 0.001), which was not evident in the following weeks (p > 0.05). Although functional recovery halted after week 2, outcome scores remained significantly higher than the pretreatment values at all weeks (p < 0.001). Although a single subacromial lornoxicam injection provides rapid functional recovery, which partially extends into the intermediate term, its results are inferior to betamethasone and it may be an alternative only in patients where corticosteroids are contraindicated. | en_US |
dc.identifier.citation | Aksakal, M. vd. (2017). ''Lornoxicam injection is inferior to betamethasone in the treatment of subacromial impingement syndrome: A prospective randomized study of functional outcomes''. Orthopade, 46(2), 179-185. | en_US |
dc.identifier.endpage | 185 | tr_TR |
dc.identifier.issn | 0085-4530 | |
dc.identifier.issn | 1433-0431 | |
dc.identifier.issue | 2 | tr_TR |
dc.identifier.pubmed | 27468823 | tr_TR |
dc.identifier.scopus | 2-s2.0-84980049417 | tr_TR |
dc.identifier.startpage | 179 | tr_TR |
dc.identifier.uri | https://doi.org/10.1007/s00132-016-3302-5 | |
dc.identifier.uri | https://link.springer.com/article/10.1007/s00132-016-3302-5 | |
dc.identifier.uri | http://hdl.handle.net/11452/31161 | |
dc.identifier.volume | 46 | tr_TR |
dc.identifier.wos | 000394313700010 | tr_TR |
dc.indexed.pubmed | PubMed | en_US |
dc.indexed.scopus | Scopus | en_US |
dc.indexed.wos | SCIE | en_US |
dc.language.iso | en | en_US |
dc.publisher | Springer | en_US |
dc.relation.collaboration | Sanayi | tr_TR |
dc.relation.journal | Orthopade | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi | tr_TR |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Orthopedics | en_US |
dc.subject | Complications | en_US |
dc.subject | Nonsteroidal anti-inflammatory drugs | en_US |
dc.subject | Questionnaires | en_US |
dc.subject | Shoulder | en_US |
dc.subject | Steroids | en_US |
dc.subject | Arthroscopic knee surgery | en_US |
dc.subject | Double-blind | en_US |
dc.subject | Corticosteroid injections | en_US |
dc.subject | Controlled-trial | en_US |
dc.subject | Articular-cartilage | en_US |
dc.subject | Intraarticular application | en_US |
dc.subject | Painful shoulder | en_US |
dc.subject | Trigger finger | en_US |
dc.subject | Tenoxicam | en_US |
dc.subject | Efficacy | en_US |
dc.subject.emtree | Antiinflammatory agent | en_US |
dc.subject.emtree | Betamethasone | en_US |
dc.subject.emtree | Lornoxicam | en_US |
dc.subject.emtree | Piroxicam | en_US |
dc.subject.emtree | Aged | en_US |
dc.subject.emtree | Analogs and derivatives | en_US |
dc.subject.emtree | Bursitis | en_US |
dc.subject.emtree | Controlled study | en_US |
dc.subject.emtree | Convalescence | en_US |
dc.subject.emtree | Dose response | en_US |
dc.subject.emtree | Drug effects | en_US |
dc.subject.emtree | Female | en_US |
dc.subject.emtree | Human | en_US |
dc.subject.emtree | Intraarticular drug administration | en_US |
dc.subject.emtree | Joint characteristics and functions | en_US |
dc.subject.emtree | Male | en_US |
dc.subject.emtree | Middle aged | en_US |
dc.subject.emtree | Randomized controlled trial | en_US |
dc.subject.emtree | Shoulder impingement syndrome | en_US |
dc.subject.emtree | Tendinopathy | en_US |
dc.subject.emtree | Treatment outcome | en_US |
dc.subject.mesh | Aged | en_US |
dc.subject.mesh | Anti-Inflammatory agents | en_US |
dc.subject.mesh | Betamethasone | en_US |
dc.subject.mesh | Bursitis | en_US |
dc.subject.mesh | Dose-response relationship, drug | en_US |
dc.subject.mesh | Female | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Injections, intra-articular | en_US |
dc.subject.mesh | Male | en_US |
dc.subject.mesh | Middle aged | en_US |
dc.subject.mesh | Piroxicam | en_US |
dc.subject.mesh | Range of motion, articular | en_US |
dc.subject.mesh | Recovery of function | en_US |
dc.subject.mesh | Shoulder impingement syndrome | en_US |
dc.subject.mesh | Tendinopathy | en_US |
dc.subject.mesh | Treatment outcome | en_US |
dc.subject.scopus | Postoperative Pain; Arthroscopy; Local Anesthetic Agent | en_US |
dc.subject.wos | Orthopedics | en_US |
dc.title | Lornoxicam injection is inferior to betamethasone in the treatment of subacromial impingement syndrome: A prospective randomized study of functional outcomes | en_US |
dc.title.alternative | Unterlegenheit der Lornoxicaminjektion gegenüber Betamethason in der Therapie des subakromialen Impingementsyndroms: Prospektive randomisierte Studie zu funktionellen Ergebnissen. | de |
dc.type | Article | |
dc.wos.quartile | Q4 | en_US |
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