Prevalence of and risk factors for cognitive impairment in patients with relapsing-remitting multiple sclerosis: Multi-center, controlled trial
dc.contributor.author | Özakbaş, Serkan | |
dc.contributor.author | Türkoğlu, Recai | |
dc.contributor.author | Tamam, Yusuf | |
dc.contributor.author | Terzi, Murat | |
dc.contributor.author | Yücesan, Canan | |
dc.contributor.author | Limoncu Baser, Hatice | |
dc.contributor.author | Gencer, Mehmet | |
dc.contributor.author | Akıl, Eşref | |
dc.contributor.author | Sen, Sedat | |
dc.contributor.author | Yiğit, Pınar | |
dc.contributor.buuauthor | Taşkapılıoğlu, Özlem | |
dc.contributor.buuauthor | Turan, Ömer Faruk | |
dc.contributor.buuauthor | Türkeş, Nevin | |
dc.contributor.department | Uludağ Üniversitesi/Tıp Fakültesi/Nöroloji Beyin ve Sinir Hastalıkları Anabilim Dalı. | tr_TR |
dc.contributor.orcid | 0000-0003-4436-3797 | tr_TR |
dc.contributor.researcherid | AAK-6623-2020 | |
dc.contributor.researcherid | JDI-6091-2023 | |
dc.contributor.researcherid | EAD-0629-2022 | |
dc.contributor.scopusid | 23037226400 | tr_TR |
dc.contributor.scopusid | 23037113500 | tr_TR |
dc.contributor.scopusid | 35886020700 | tr_TR |
dc.date.accessioned | 2024-01-26T06:23:24Z | |
dc.date.available | 2024-01-26T06:23:24Z | |
dc.date.issued | 2018-05 | |
dc.description.abstract | Background: Cognitive impairment (CI) is a common problem in multiple sclerosis (MS), may occur either in early or late phase of the disease, and impairs quality of life. Objectives: This study aimed to determine the prevalence of CI and related risk factors in relapsing-remitting MS (RRMS) patients in Turkey. Methods: The present cross-sectional, multi-center, and nationally representative study included RRMS patients. Sociodemographic characteristics, cognitive functions and additional outcomes were compared between patients with and without CI. Results: The analyses included 487 RRMS patients. According to the BRB-N battery results, CI prevalence was 53.7%. There was a negative significant correlation of BRB-N subtests with age, disease duration, and EDSS and MSNQ-patient rated scores. On the logistic regression analysis, increased age, living in village/rural area, high income level, and high EDSS score were significant increasing risk factors in the development of CI. Conclusions: This is the first national cognitive data obtained from MS in Turkey, which is a country between Europe and Asia and thus has characteristics of both continents. The similarity of the results of the present study obtained from Turkey to the Western-based data indicates that CI is universal in MS and the main factors affecting CI have not changed. | en_US |
dc.description.sponsorship | MS Research Association | en_US |
dc.identifier.citation | Özakbaş, S. vd. (2018). ''Prevalence of and risk factors for cognitive impairment in patients with relapsing-remitting multiple sclerosis: Multi-center, controlled trial''. Multiple Sclerosis and Related Disorders, 22, 70-76. | en_US |
dc.identifier.doi | https://doi.org/10.1016/j.msard.2018.03.009 | |
dc.identifier.endpage | 76 | tr_TR |
dc.identifier.issn | 2211-0348 | |
dc.identifier.issn | 2211-0356 | |
dc.identifier.pubmed | 29605801 | tr_TR |
dc.identifier.scopus | 2-s2.0-85044620700 | tr_TR |
dc.identifier.startpage | 70 | tr_TR |
dc.identifier.uri | https://www.sciencedirect.com/science/article/pii/S2211034818300968 | |
dc.identifier.uri | https://hdl.handle.net/11452/39333 | |
dc.identifier.volume | 22 | tr_TR |
dc.identifier.wos | 000433294800016 | tr_TR |
dc.indexed.pubmed | PubMed | en_US |
dc.indexed.scopus | Scopus | en_US |
dc.indexed.wos | SCIE | en_US |
dc.indexed.wos | SSCI | en_US |
dc.language.iso | en | en_US |
dc.publisher | Elsevier | en_US |
dc.relation.collaboration | Yurt içi | tr_TR |
dc.relation.collaboration | Sanayi | tr_TR |
dc.relation.journal | Multiple Sclerosis and Related Disorders | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi | tr_TR |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Neurosciences & neurology | en_US |
dc.subject | Multiple sclerosis | en_US |
dc.subject | Cognition | en_US |
dc.subject | Prognosis | en_US |
dc.subject | Prevalence | en_US |
dc.subject | Brief repeatable battery | en_US |
dc.subject | Qyality-of-life | en_US |
dc.subject | Follow-up | en_US |
dc.subject | Dysfunction | en_US |
dc.subject | Population | en_US |
dc.subject | Depression | en_US |
dc.subject | Disability | en_US |
dc.subject | MS | en_US |
dc.subject.emtree | Adult | en_US |
dc.subject.emtree | Age | en_US |
dc.subject.emtree | Article | en_US |
dc.subject.emtree | Cognition | en_US |
dc.subject.emtree | Cognitive defect | en_US |
dc.subject.emtree | Cognitive function test | en_US |
dc.subject.emtree | Comparative study | en_US |
dc.subject.emtree | Controlled study | en_US |
dc.subject.emtree | Cross-sectional study | en_US |
dc.subject.emtree | Demography | en_US |
dc.subject.emtree | Disease association | en_US |
dc.subject.emtree | Disease duration | en_US |
dc.subject.emtree | Disease predisposition | en_US |
dc.subject.emtree | Expanded disability status scale | en_US |
dc.subject.emtree | Female | en_US |
dc.subject.emtree | Highest income group | en_US |
dc.subject.emtree | Human | en_US |
dc.subject.emtree | Major clinical study | en_US |
dc.subject.emtree | Male | en_US |
dc.subject.emtree | Multicenter study | en_US |
dc.subject.emtree | Multiple sclerosis | en_US |
dc.subject.emtree | Multiple sclerosis neuropsychological questionnaire | en_US |
dc.subject.emtree | Prevalence | en_US |
dc.subject.emtree | Risk factor | en_US |
dc.subject.emtree | Rural population | en_US |
dc.subject.emtree | Social status | en_US |
dc.subject.emtree | Turkey (republic) | en_US |
dc.subject.emtree | Clinical trial | en_US |
dc.subject.emtree | Cognitive defect | en_US |
dc.subject.emtree | Complication | en_US |
dc.subject.emtree | Disability | en_US |
dc.subject.emtree | Educational status | en_US |
dc.subject.emtree | Multiple sclerosis | en_US |
dc.subject.emtree | Neuropsychological test | en_US |
dc.subject.emtree | Prevalence | en_US |
dc.subject.emtree | Psychology | en_US |
dc.subject.emtree | Risk factor | en_US |
dc.subject.emtree | Time factor | en_US |
dc.subject.emtree | Turkey (bird) | en_US |
dc.subject.mesh | Adult | en_US |
dc.subject.mesh | Age factors | en_US |
dc.subject.mesh | Cognitive dysfunction | en_US |
dc.subject.mesh | Cross-sectional studies | en_US |
dc.subject.mesh | Disability evaluation | en_US |
dc.subject.mesh | Educational status | en_US |
dc.subject.mesh | Female | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Male | en_US |
dc.subject.mesh | Multiple sclerosis, relapsing-remitting | en_US |
dc.subject.mesh | Neuropsychological tests | en_US |
dc.subject.mesh | Prevalence | en_US |
dc.subject.mesh | Risk factors | en_US |
dc.subject.mesh | Time factors | en_US |
dc.subject.mesh | Turkey | en_US |
dc.subject.scopus | Multiple Sclerosis; Neuropsychological Tests; Cognition | en_US |
dc.subject.wos | Clinical neurology | en_US |
dc.title | Prevalence of and risk factors for cognitive impairment in patients with relapsing-remitting multiple sclerosis: Multi-center, controlled trial | en_US |
dc.type | Article | en_US |
dc.wos.quartile | Q2 | en_US |
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