A short and efficient asymmetric synthesis of (±)-epi-cytoxazone from cis-(1R,2S,5R)-menthyl 4-methoxyphenylglycidates
dc.contributor.author | Er, Mustafa | |
dc.contributor.buuauthor | Coşkun, Necdet F. | |
dc.contributor.department | Uludağ Üniversitesi/Fen Edebiyat Fakültesi/Kimya Bölümü. | tr_TR |
dc.contributor.researcherid | B-1200-2012 | tr_TR |
dc.contributor.scopusid | 7004177880 | tr_TR |
dc.date.accessioned | 2024-01-16T06:46:45Z | |
dc.date.available | 2024-01-16T06:46:45Z | |
dc.date.issued | 2014-12 | |
dc.description.abstract | The racemic epi-cytoxazone was synthesized, starting from p-anisaldehyde, in five steps and 48% overall yield. An efficient synthesis of azido alcohols has been achieved by regioselective ring opening of glycidates using NaN3 in MeOH-H2O. The key step of the process is reductive cyclization of azide carbonates by Zn-TMSCl. | en_US |
dc.identifier.citation | Coşkun, N. F. ve Er, M. (2014). "A short and efficient asymmetric synthesis of (±)-epi-cytoxazone from cis-(1R,2S,5R)-menthyl 4-methoxyphenylglycidates". Chemistry of Natural Compounds, 50(6), 1071-1074. | en_US |
dc.identifier.endpage | 1074 | tr_TR |
dc.identifier.issn | 0009-3130 | |
dc.identifier.issn | 1573-8388 | |
dc.identifier.issue | 6 | tr_TR |
dc.identifier.scopus | 2-s2.0-84922105242 | tr_TR |
dc.identifier.startpage | 1071 | tr_TR |
dc.identifier.uri | https://doi.org/10.1007/s10600-014-1161-z | |
dc.identifier.uri | https://link.springer.com/article/10.1007/s10600-014-1161-z | |
dc.identifier.uri | https://hdl.handle.net/11452/39045 | |
dc.identifier.volume | 50 | tr_TR |
dc.identifier.wos | 000345771400023 | |
dc.indexed.pubmed | PubMed | en_US |
dc.indexed.wos | SCIE | |
dc.indexed.wos | IC | |
dc.language.iso | en | en_US |
dc.publisher | Springer | en_US |
dc.relation.collaboration | Yurt içi | tr_TR |
dc.relation.journal | Chemistry of Natural Compounds | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi | tr_TR |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | (±)-epi-cytoxazone | en_US |
dc.subject | Zn-TMSCl reduction | en_US |
dc.subject | 4-methoxyphenylglycidate | en_US |
dc.subject | Darzen epoxidation | en_US |
dc.subject | Azides | en_US |
dc.subject | Stereoselective-synthesis | en_US |
dc.subject | Cytokine modulator | en_US |
dc.subject | (+)-epi-cytoxazone | en_US |
dc.subject | Cytoxazone | en_US |
dc.subject | (-)-cytoxazone | en_US |
dc.subject | Pharmacology & pharmacy | en_US |
dc.subject | Chemistry | en_US |
dc.subject.scopus | Cytoxazone; Ester; Stereochemistry | en_US |
dc.subject.wos | Chemistry, medicinal | en_US |
dc.subject.wos | Chemistry, organic | en_US |
dc.title | A short and efficient asymmetric synthesis of (±)-epi-cytoxazone from cis-(1R,2S,5R)-menthyl 4-methoxyphenylglycidates | en_US |
dc.type | Article | en_US |
dc.wos.quartile | Q4 |
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