Familyal periodik paraliziler (8 olgunun analizi)
Date
1992
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Uludağ Üniversitesi
Abstract
Familyal periyodik paralizi (FPP), birkaç saatten, birkaç güne kadar süren flask parezi atakları ile karakterize nadir bir kas hastalığıdır. Ataklar anında serum K + değerlerine göre hipokalemik, normokalemik ve hiperkalemik FPP tanımlanmıştır. Hastalık patogenezi bilinmemekle birlikte kas hücre membranında sodyum potasyum iyon transport mekanizmasında tutulum olabilir. Bu çalışmada 1973-1991 yılları arasında 8 FPP'li hasta değerlendirildi. Bu hastaların 7'si hipokalemik,1'i normokalemik idi. Kas biyopsisinde, 2 hastada tipik vakuoller görüldü.
Familial periodic paralysis (FPP) is a rare muscle disease characterised by attacks of flaccid paresis lasting from a few hours to several days. FPPs have been defined as hypokalemic, hypokalemic and hyperkalemic according to serum K+ levels during attacks. The pathogenesis of the disorder is unknown but may involve sodium-potassium ion transport mechanism across the muscle cell membrane. In this study we have evaluated 8 patients with FPP between 1973 and 1991. One of them was normokalemic and seven were hypokalemic. The muscle biopsy showed typical vacuoles in 2 patients.
Familial periodic paralysis (FPP) is a rare muscle disease characterised by attacks of flaccid paresis lasting from a few hours to several days. FPPs have been defined as hypokalemic, hypokalemic and hyperkalemic according to serum K+ levels during attacks. The pathogenesis of the disorder is unknown but may involve sodium-potassium ion transport mechanism across the muscle cell membrane. In this study we have evaluated 8 patients with FPP between 1973 and 1991. One of them was normokalemic and seven were hypokalemic. The muscle biopsy showed typical vacuoles in 2 patients.
Description
Keywords
Familyal periodik paraliziler, Paraliziler, Kas hastalıkları, Muscular diseases
Citation
Turan, Ö. F. vd. (1992). ''Familyal periodik paraliziler (8 olgunun analizi) ''. Uludağ Üniversitesi Tıp Fakültesi Dergisi, 19(2), 241-247.