Riskli yenidoğanların nöromotor açıdan bir yıllık prognozu
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Date
1993-06-16
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Uludağ Üniversitesi
Abstract
Uludağ Üniversitesi Tıp Fakültesi Pediatri klini'ne Ocak 1989-0cak 1990 tarihleri arasında yaşamının ilk 7 gününde yatırılan riskli 105 yeni doğan bebek çalışmaya alındı. Riskli yeni doğanların 1 yıl süreli nöromotor gelişimlerinin incelenmesi ve serebral palsi gibi nörolojik sekelleri erken dönemde saptanabilmesi için prospektif bir çalışma planlandı. Olgular prematüre (% I9), neonatal sepsis(% 29) neonatal menenjit (% I8) ve hipoksik iskemik ensefalopati olmak üzere 4 grupta incelenir. 1 yıl sonra, % 21 olguda serebral palsi dahil ciddi nörolojik sekel gelişti, % 27 olguda nöromotor yönden gerilik saptandı. % 52 olgunun gelişimi normal olarak değerlendirildi. En yüksek sekel oranı hipoksik iskemik ensefalopati grubunda rasiandı (p<O. 0001). Nörolojik sekel ve nöromotor geriliği oluşmasında ortalama 3.5±2.I ayda şüphelenildi ve ortalama 8± 2.5 ayda anı konuldu.
A consecutive series of 105 infants at risk, aged 1-7 days, coming to out clinic from January 1989 to January 1990 were studied. To investigate ne uromotor outcome for one year and early detection of cerebral palsy and other significant neurologic sequelae in the infants at risk during their first week after birth we performed a prospective clinical study. Patients were initially classified into four groups as premature infants (19 %), neonatal sepsis (29 %), neonatal meningitis (I 8 %) and hypoxic ischemic encepha/opathy (34 %). After one year significant sequelae including cerebral palsy occurred in 21 % and neuro-motor retardation in 27 % survivors. 52 percent of cases were evaluated as normally. The highest rate of sequelae and neuro-motor retardation was in the hypoxic ischemic encephalopathy group. The average sequa/e and neuro-motor retardation was initia/ly suspected at 3. 5 ±2.1 months and diagnosed at 8±2.5 months.
A consecutive series of 105 infants at risk, aged 1-7 days, coming to out clinic from January 1989 to January 1990 were studied. To investigate ne uromotor outcome for one year and early detection of cerebral palsy and other significant neurologic sequelae in the infants at risk during their first week after birth we performed a prospective clinical study. Patients were initially classified into four groups as premature infants (19 %), neonatal sepsis (29 %), neonatal meningitis (I 8 %) and hypoxic ischemic encepha/opathy (34 %). After one year significant sequelae including cerebral palsy occurred in 21 % and neuro-motor retardation in 27 % survivors. 52 percent of cases were evaluated as normally. The highest rate of sequelae and neuro-motor retardation was in the hypoxic ischemic encephalopathy group. The average sequa/e and neuro-motor retardation was initia/ly suspected at 3. 5 ±2.1 months and diagnosed at 8±2.5 months.
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Keywords
Riskli yenidoğan, Nöromotor gelişim, Serebral palsi, At risk infant, Neuro-motor outcome, Cerebral palsy
Citation
Eralp, Ö. vd. (1993). ''Riskli yenidoğanların nöromotor açıdan bir yıllık prognozu''. Uludağ Üniversitesi Tıp Fakültesi Dergisi, 20(3), 265-271.