Effects of neuronotrophic factors on adrenal medulla grafts implanted into adult rat brains

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dc.contributor.authorRakunt, Cemil
dc.contributor.buuauthorKorfalı, Ender
dc.contributor.buuauthorDoygun, Muammer
dc.contributor.buuauthorUlus, İsmail Hakkı
dc.contributor.buuauthorAksoy, Kaya
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Beyin Cerrahisi Anabilim Dalı.tr_TR
dc.contributor.researcheridD-5340-2015tr_TR
dc.date.accessioned2021-07-05T05:27:50Z
dc.date.available2021-07-05T05:27:50Z
dc.date.issued1988-06-01
dc.description.abstractThe effects of neuronotrophic factors (NFs) on adult adrenal medulla grafts transplanted into the rat caudate nucleus after the destruction of the nigrostriatal dopaminergic pathways were investigated. Two months after implantation, all of the adrenal medulla grafts treated with NFs, but only 45% of the untreated grafts, had survived. The levels of tyrosine hydroxylase activity in the caudate nucleus however, were not significantly different between the sham-operated control and either NF-treated or untreated grafted groups. These results indicate that treatment with NFs significantly enhances the survival rate of the grafts.en_US
dc.identifier.citationKorfalı, E. vd. (1988). ''Effects of neuronotrophic factors on adrenal medulla grafts implanted into adult rat brains''. Neurosurgery, 22(6), 994-998.en_US
dc.identifier.endpage998tr_TR
dc.identifier.issn0148-396X
dc.identifier.issue6tr_TR
dc.identifier.pubmed2901688tr_TR
dc.identifier.scopus2-s2.0-0023765544tr_TR
dc.identifier.startpage994tr_TR
dc.identifier.urihttps://doi.org/10.1227/00006123-198806010-00003
dc.identifier.urihttps://academic.oup.com/neurosurgery/article-abstract/22/6P1-P2/994/2746110
dc.identifier.urihttp://hdl.handle.net/11452/21018
dc.identifier.volume22tr_TR
dc.identifier.wosA1988P465900003
dc.indexed.pubmedPubmeden_US
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherOxford Univ Pressen_US
dc.relation.collaborationYurt içitr_TR
dc.relation.journalNeurosurgerytr_TR
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectNeurosciences & neurologyen_US
dc.subjectSurgeryen_US
dc.subjectCorpus striatumen_US
dc.subjectTyrosine hydroxylaseen_US
dc.subjectAdrenal medullaen_US
dc.subjectTransplantationen_US
dc.subjectReinnervationen_US
dc.subjectBrain graften_US
dc.subject.wosClinical neurologyen_US
dc.subject.wosSurgeryen_US
dc.titleEffects of neuronotrophic factors on adrenal medulla grafts implanted into adult rat brainsen_US
dc.typeArticle

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