Anne sütüyle beslenmenin invitro lökosit fonksiyonlarına etkisi
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Date
1981
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Bursa Üniversitesi
Abstract
Süt çocuklarında anne sütüyle beslenmenin, invitro lökosit fonksiyanlarına etkisi ncelendi. Anne sütü alan ve almayan çocukların, serum opsonik aktivitesi, lökositlerin fagositoz indeksi, bakterisidal aktivitesi ve NBT boyasını indirgeme yeteneği araştırıldı. Anne sütü alan bebeklerde Staphylococcus aureus'a karşı opsonik aktivite yüksek bulundu. Lökositlerin fagositik ve bakterisidal aktivitesi ise, gerek anne sütüyle gerekse yapay beslenenlerde değişiklik göstermedi. Buna karşılık NBT-testi yapay sütle beslenen çocuklarda iki kat artmış olarak bulundu. Sonuç olarak; lökositlerin antibakteriyel fonksiyolarının anne sütü almayan çocuklarda azalmış olması: bu çocukların enfeksiyonlara duyarlılığının artmasına neden olabileceğini düşündürmüştür.
In infants the effect of feeding of colostrum and milk on their invitro leukocyte functions were determined. Serum opsonic activity, phagocytic and bactericidal activities of leukocytes of breast- fed and formula- fed infants were examined. NBT- dye reduction ability of leukocytes were also investigated in two groups. The opsonic activity againts Staphylococcus aureus had increased in breast - fed infants. There was no difference between two groups in phagocytic and killing activities of leukocytes. Bul NBT-test increased two fold positivity in formula - fed infants. This study indicates that leukocytic antibacteriel function decreased in formula - fed infants and this may be an addilional mechanism of infant's increased susceptibility to infection.
In infants the effect of feeding of colostrum and milk on their invitro leukocyte functions were determined. Serum opsonic activity, phagocytic and bactericidal activities of leukocytes of breast- fed and formula- fed infants were examined. NBT- dye reduction ability of leukocytes were also investigated in two groups. The opsonic activity againts Staphylococcus aureus had increased in breast - fed infants. There was no difference between two groups in phagocytic and killing activities of leukocytes. Bul NBT-test increased two fold positivity in formula - fed infants. This study indicates that leukocytic antibacteriel function decreased in formula - fed infants and this may be an addilional mechanism of infant's increased susceptibility to infection.
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Keywords
Anne sütüyle beslenme, İnvitro lökosit fonksiyonları, Human milk, Invitro leukocyte functions
Citation
Özcenk, N. ve Ildırım, İ. (1981). "Anne sütüyle beslenmenin invitro lökosit fonksiyonlarına etkisi". Bursa Tıp Fakültesi Dergisi, 8(2), 139-148.