5′ MLL gene deletion in a case with childhood acute lymphoblastic leukemia

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dc.contributor.buuauthorGülten, Tuna
dc.contributor.buuauthorYakut, Tahsin
dc.contributor.buuauthorGüneş, Adalet Meral
dc.contributor.buuauthorDemirkaya, Metin
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Tıbbi Genetik Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Çocuk Sağlığı ve Hastalıkları Anabilim Dalı.tr_TR
dc.contributor.scopusid6505944216tr_TR
dc.contributor.scopusid6602802424tr_TR
dc.contributor.scopusid24072843300tr_TR
dc.contributor.scopusid24331130000tr_TR
dc.date.accessioned2022-03-16T11:43:18Z
dc.date.available2022-03-16T11:43:18Z
dc.date.issued2010-02
dc.description.abstractMyeloid/lymphoid leukemia (MLL) gene rearrangements are high risk cytogenetic characteristics of acute lymphoblastic leukemia (ALL). Translocations of this gene are well defined, and their impact on the patient's prognosis is well known, but deletions of the same region are rare, and little is known about their prognostic significance and the significance of their accompanying translocations. Here we present a case of childhood ALL with a deletion of the 5' region of the MILL gene detected by fluorescence in situ hybridization (FISH) analysis, This result also confirmed the sensitivity and efficiency of FISH analysis.en_US
dc.identifier.citationGülten, T. vd. (2010). "5′ MLL gene deletion in a case with childhood acute lymphoblastic leukemia". Laboratory Medicine, 41(2), 83-86.en_US
dc.identifier.endpage86tr_TR
dc.identifier.issn0007-5027
dc.identifier.issue2tr_TR
dc.identifier.scopus2-s2.0-77951949544tr_TR
dc.identifier.startpage83tr_TR
dc.identifier.urihttps://doi.org/10.1309/LMC5LW0IMKNG5LCN
dc.identifier.urihttps://academic.oup.com/labmed/article/41/2/83/2504871
dc.identifier.urihttp://hdl.handle.net/11452/25089
dc.identifier.volume41tr_TR
dc.identifier.wos000273940800003
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherOxford Universityen_US
dc.relation.journalLaboratory Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMLL gene deletionen_US
dc.subjectAcute Lymphoblastic Leukemiaen_US
dc.subjectFISH analysisen_US
dc.subjectHemotological malignanciesen_US
dc.subjectRearrangementen_US
dc.subjectTranslocationsen_US
dc.subjectIdentificationen_US
dc.subjectAbnormalitiesen_US
dc.subjectAberrationsen_US
dc.subjectApoptosisen_US
dc.subject11Q23en_US
dc.subjectProbeen_US
dc.subjectFishen_US
dc.subjectMedical laboratory technologyen_US
dc.subject.emtreeAcute lymphocytic leukemiaen_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeCase reporten_US
dc.subject.emtreeChilden_US
dc.subject.emtreeChildhood leukemiaen_US
dc.subject.emtreeCytogeneticsen_US
dc.subject.emtreeFluorescence in situ hybridizationen_US
dc.subject.emtreeGene deletionen_US
dc.subject.emtreeGene rearrangementen_US
dc.subject.emtreeGene translocationen_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeMaleen_US
dc.subject.emtreeMll geneen_US
dc.subject.emtreeOncogeneen_US
dc.subject.emtreePreschool childen_US
dc.subject.emtreePrognosisen_US
dc.subject.emtreeSensitivity and specificityen_US
dc.subject.scopusEPZ-5676; Myeloid-Lymphoid Leukemia Protein; Acute Lymphoblastic Leukemiaen_US
dc.subject.wosMedical laboratory technologyen_US
dc.title5′ MLL gene deletion in a case with childhood acute lymphoblastic leukemiaen_US
dc.typeArticle

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