Acute effect of centrally injected Nesfatin-1 on some blood electrolytes and metabolites in rats

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dc.contributor.buuauthorBayram, Gökçen Güvenç
dc.contributor.buuauthorÜlger, Ebru Yalçın
dc.contributor.buuauthorYalçın, Murat
dc.contributor.departmentBursa Uludağ Üniversitesi/Veteriner Fakültesi/Fizyoloji Anabilim Dalı.tr_TR
dc.contributor.orcid0000-0002-1413-3651tr_TR
dc.contributor.orcid0000-0003-1756-1288tr_TR
dc.contributor.orcid0000-0002-5600-8162tr_TR
dc.date.accessioned2022-07-27T10:43:30Z
dc.date.available2022-07-27T10:43:30Z
dc.date.issued2020-11-18
dc.description.abstractNesfatin-1 is a newly found food and water intake regulatory neuropeptide. Because it can regulate nutrition and thirst, nesfatin-1 may also have the potential to affect levels of blood electrolytes and metabolites. The current study was intended to resolve the acute influence of intra- cerebroventricularly injected nesfatin-1 on the levels of some blood electrolytes and metabolites in rats. The experiments were conducted on Sprague Dawley male rats. Nesfatin-1 (200 pmol) or saline (5 μL) was given the rats intracerebroven- tricularly. Central nesfatin-1 treatment caused increases in the concentrations of blood glucose, lactate, hematocrit, and hemoglobin without changing the blood pH, creatine, Na, K, Ca, Cl, and HCO3 levels. In conclusion, our findings show that the central nesfatin-1 could affect the concentrations of blood glucose, lactate, hematocrit, and hemo- globin without altering the blood electrolytes. This could be interpreted as the secondary effect of nesfatin-1 as a consequence of centrally injected nesfatin-1-evoked activation of sympathetic nerves.tr_TR
dc.identifier.citationBayram, G. G. vd. (2020). "Acute effect of centrally injected Nesfatin-1 on some blood electrolytes and metabolites in rats". Veteriner Hekimlikte Araştırma Dergisi, 39(2), 149-152.tr_TR
dc.identifier.endpage152tr_TR
dc.identifier.issn1301-3173
dc.identifier.issue2tr_TR
dc.identifier.startpage149tr_TR
dc.identifier.urihttps://doi.org/10.30782/jrvm.735993
dc.identifier.urihttps://dergipark.org.tr/tr/download/article-file/1480620
dc.identifier.urihttp://hdl.handle.net/11452/28055
dc.identifier.volume39tr_TR
dc.language.isoenen_US
dc.publisherBursa Uludağ Üniversitesitr_TR
dc.relation.journalVeteriner Hekimlikte Araştırma Dergisi / Journal of Research in Veterinary Medicinetr_TR
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectNesfatin-1tr_TR
dc.subjectIntracerebroventriculartr_TR
dc.subjectBlood electrolytesen_US
dc.subjectBlood metabolitesen_US
dc.subjectHematocriten_US
dc.subjectHemoglobinen_US
dc.titleAcute effect of centrally injected Nesfatin-1 on some blood electrolytes and metabolites in ratsen_US
dc.typeArticleen_US

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2020 Cilt 39 Sayı 2