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Browsing by BUU Author "Akesen, Burak"

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    Comparative results of percutaneous cannulated screws, dynamic compression type plate and screw for the treatment of femoral neck fractures
    (Türk Travma ve Acil Cerrahi Dergisi, 2012-01) Kaplan, Tolga; Akesen, Burak; Demirağ, Burak; Bilgen, Sadık; Durak, Kemal; Uludağ Üniversitesi/Tıp Fakültesi/Ortopedi ve Travmatoloji Anabilim Dalı.; AAI-1638-2021; AAH-9833-2021; 23102160500; 56019156900; 15061239900; 6602850051
    BACKGROUND The purpose of this study was to compare the period of union, functional outcomes and complications of patients with femoral neck fracture treated with percutaneous cannulated screws versus dynamic hip screw (DHS). METHODS Sixty-six patients with femoral neck fracture were treated with percutaneous cannulated screws (n=33) or with DHS (n=33) between August 1999 and October 2003. Functional outcome was measured using Harris Hip Score, and period of union, amount of bleeding and complications were also recorded. RESULTS The period of union and functional outcomes were not different between the two groups. Risk of avascular necrosis (AVN) was associated mainly with the grade of fracture displacement. In the percutaneous cannulated screw group, duration of surgery was shorter and blood loss was less than in the other group. CONCLUSION There was no superiority between cannulated screws and DHS according to union times and functional results. Risk of AVN is related to the degree of displacement. However, a prospective randomized study is needed to determine the outcome of each technique for patients suffering similar displacement rates.
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    Evaluation of intraarticular collagenase, TIMP-1, and TNF-α levels before and after anterior cruciate ligament reconstruction
    (Türk Ortopedi ve Travmatoloji Birliği Derneği, 2009) Akesen, Burak; Demirağ, Burak; Budak, Ferah; Uludağ Üniversitesi/Tıp Fakültesi/Ortopedi ve Travmatoloji Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Enfeksiyon Hastalıkları ve Mikrobiyoloji Anabilim Dalı.; AAH-9833-2021; F-4657-2014; 23102160500; 56019156900; 6701913697
    Objectives: We investigated intra-articular levels of collagenase, which presumably promotes bone-tendon healing, and collagenase mediators involved in its production (tumor necrosis factor-alpha, TNF-alpha) and inhibition (TIMP-1 enzyme) in patients following anterior cruciate ligament (ACL) reconstruction. Methods: The study included 16 patients (15 males, 1 female; mean age 27 years; range 17 to 40 years) who underwent arthrocentesis due to effusion that developed following reconstruction of isolated ACL injuries. Intra-articular levels of collagenase, TNF-alpha, and TIMP-1 were measured using appropriate activity assay and immunoassay kits in synovial fluid samples obtained intraoperatively and during arthrocentesis. The mean time from ACL injury to surgical repair was 21 +/- 10 months (range 1 to 72 months). Arthrocentesis was performed in a mean of 18 hours (range 12 to 36 hours) following ACL repair. Results: Measurements in synovial fluid samples obtained intra- and postoperatively yielded 1.49 +/- 0.06 ng/ml and 1.45 +/- 0.05 ng/ml for collagenase, 12 +/- 5 ng/ml and 22 +/- 9.5 ng/ml for TIMP-1, and 10.4 +/- 7.1 pr/ml and 14.11 +/- 6.1 pr/ml for TNF-alpha, respectively. Postoperative changes in the levels of collagenase (p=0.098) and TNF-alpha (p=0.069) were not significant, whereas increase in the TIMP-1 level was significant (p=0.026). Conclusion: This study showed elevated levels of TNF-alpha, collagenase, and TIMP-1 due to the presence of ruptured ACL. Our findings showed how these levels changed in the acute postoperative period.
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    Long-term outcome of unreamed intramedullary nails in femur diaphyseal fractures
    (Türk Travma ve Acil Cerrahi Derneği, 2012-03) Özdemir, Bülent; Akesen, Burak; Demirağ, Burak; Bilgen, Muhammed Sadık; Durak, Kemal; Uludağ Üniversitesi/Tıp Fakültesi/Ortopedi ve Travmatoloji Anabilim Dalı.; AAH-9833-2021; 7004168959; 23102160500; 56019156900; 35723877700; 6602850051
    BACKGROUND: We evaluated the results of patients with traumatic femur diaphyseal fracture who had undergone biologic fixation with unreamed intramedullary nailing. METHODS: Twenty-five adults with 29 traumatic femur diaphyseal fractures who had undergone unreamed intramedullary nailing at Uludag University School of Medicine, Department of Orthopedics and Traumatology were included in the study between January 1997 and December 2007. Gender, age, cause of injury, fracture type, operation length, time lapse till surgery, blood loss, fluoroscopy duration, early and late complications, time until union, and functional results were noted. Functional results were evaluated with Klemm-Borner and Thoresen systems and Short Form (SF)-36 health survey questions. RESULTS: The mean follow-up of the patients was 65.1 +/- 31.6 months (26-138). There was no statistically significant difference between operation length, blood loss and time until union of simple and complex fractures (p>0.05). Furthermore, the SF-36 questionnaire revealed no statistically significant difference between pain scores (p>0.05). CONCLUSION: Sparing of the endosteal and periosteal circulation, low infection and high union rates, and good functional outcomes of unreamed intramedullary nailing fixation make it the treatment of choice for simple and comminuted fractures of the femur shaft, especially for multi-trauma patients and patients with cardiopulmonary comorbidities.
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    Omurga kırıklı hastalarda görsel analog skala omurga skoru Türkçe versiyonunun geçerliliği
    (Türk Ortopedi ve Travmatoloji Birliği Derneği, 2011) Yaray, Osman; Akesen, Burak; Ocaklıoǧlu, Gökhan; Aydınlı, Ufuk; Uludağ Üniversitesi/Tıp Fakültesi/Ortopedi ve Travmatoloji Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Biyoistatistik Anabilim Dalı.; AAH-9833-2021; 36538242000; 23102160500; 53983054000; 6602800134
    Objective: The visual analog scale spine score (VASSS) is a valid and reliable instrument for outcome assessment of patients with thoracic and lumbar spine fractures. The aim of this study was to prepare a Turkish version of the VASSS and to validate its use for assessing treatment outcomes in Turkish patients with spinal trauma. Methods: The German version of the VASSS was blindly and independently translated into Turkish by three translators and modified by a team. Fifty patients who had been surgically treated for thoracic or lumbar fracture and a group of 50 healthy controls were evaluated using the VASSS, Oswestry Disability Index (ODI), Roland-Morris Disability Questionnaire (RMDQ), and Short Form 36 (SF-36). The Cronbach's alpha was performed to test the internal consistency of the score. Results: The Cronbach's alpha coefficient was calculated as 0.965 in the overall assessment of the scale. Criterion validity measured by comparing the VASSS responses with the results of ODI, RMDQ, and SF-36 physical component (for ODI r=0.881, p<0.001; for RMDQ r=0.882, p<0.001; for SF-36 r=0.824, p<0.001). Construct validity tested by factor analysis yielded a factorial structure of the questionnaire with 64.7% of cumulative percentage of explained variance, and Turkish version of the VASSS showed a similar structure than the original version. Conclusion: The Turkish version of the VASSS is a reliable and valid instrument to assess the outcome in patients with thoracic or lumbar spinal fractures in the Turkish population.