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Rapid emergence of colistin resistance and its impact on fatality among healthcare-associated infections

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dc.contributor.buuauthorYılmaz, Emel
dc.contributor.buuauthorAkalın, Halis
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentEnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Ana Bilim Dalı
dc.contributor.orcid0000-0002-3894-1231
dc.contributor.researcheridAAU-8952-2020
dc.contributor.scopusid22037135100
dc.contributor.scopusid57207553671
dc.date.accessioned2024-03-05T11:36:42Z
dc.date.available2024-03-05T11:36:42Z
dc.date.issued2018-03
dc.descriptionÇalışmada 31 yazar bulunmaktadır. Bu yazarlardan sadece Bursa Uludağ Üniversitesi mensuplarının girişleri yapılmıştır
dc.description.abstractThis article describes the emergence of resistance and predictors of fatality for 1556 cases of healthcare-associated Gram-negative bloodstream infection in 2014 and 2015. The colistin resistance rate in Klebsiella pneumoniae was 16.1%, compared with 6% in 2013. In total, 660 (42.4%) cases were fatal. The highest fatality rate was among patients with Acinetobacter baumannii bacteraemia (58%), followed by Pseudomonas aeruginosa (45%), Klebsiella pneumoniae (41%), Enterobacter cloacae (32%) and Escherichia coli (28%). On multi-variate analysis, the minimum inhibitory concentrations for carbapenems [odds ratio (OR) 1.02, 95% confidence interval (CI) 1.01-1.04; P = 0.002] and colistin (OR 1.1, 95% CI 1.03-1.17; P = 0.001) were found to be significantly associated with fatality.
dc.identifier.citationAydın, M. vd. (2018). ''Rapid emergence of colistin resistance and its impact on fatality among healthcare-associated infections''. Journal of Hospital Infection, 98(3), 260-263.
dc.identifier.doihttps://doi.org/10.1016/j.jhin.2017.11.014
dc.identifier.endpage263
dc.identifier.issn0195-6701
dc.identifier.issn1532-2939
dc.identifier.issue3
dc.identifier.pubmed29248504
dc.identifier.scopus2-s2.0-85044363955
dc.identifier.startpage260
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S0195670117306412
dc.identifier.urihttps://hdl.handle.net/11452/40219
dc.identifier.volume98
dc.identifier.wos000426316700011
dc.indexed.scopusScopus
dc.indexed.wosSCIE
dc.language.isoen
dc.publisherW.B. Saunders
dc.relation.collaborationYurt içi
dc.relation.collaborationSanayi
dc.relation.journalJournal of Hospital Infection
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectPublic, environmental & occupational health
dc.subjectInfectious diseases
dc.subjectBloodstream
dc.subjectGram-negative
dc.subjectHealth care
dc.subjectColistin MIC
dc.subject.emtreeCarbapenem derivative
dc.subject.emtreeColistin
dc.subject.emtreeAntiinfective agent
dc.subject.emtreeCarbapenem derivative
dc.subject.emtreeColistin
dc.subject.emtreeAcinetobacter baumannii
dc.subject.emtreeAdult
dc.subject.emtreeAntibiotic resistance
dc.subject.emtreeArticle
dc.subject.emtreeBacteremia
dc.subject.emtreeBloodstream infection
dc.subject.emtreeDrug effect
dc.subject.emtreeEnterobacter cloacae
dc.subject.emtreeEscherichia coli
dc.subject.emtreeFatality
dc.subject.emtreeFemale
dc.subject.emtreeHealthcare associated infection
dc.subject.emtreeHuman
dc.subject.emtreeKlebsiella pneumoniae
dc.subject.emtreeMajor clinical study
dc.subject.emtreeMale
dc.subject.emtreeMinimum inhibitory concentration
dc.subject.emtreeMortality rate
dc.subject.emtreePseudomonas aeruginosa
dc.subject.emtreeRetrospective study
dc.subject.emtreeAged
dc.subject.emtreeClinical trial
dc.subject.emtreeCross infection
dc.subject.emtreeGram negative bacterium
dc.subject.emtreeGram negative infection
dc.subject.emtreeIsolation and purification
dc.subject.emtreeMicrobial sensitivity test
dc.subject.emtreeMicrobiology
dc.subject.emtreeMiddle aged
dc.subject.emtreeMortality
dc.subject.emtreeMulticenter study
dc.subject.emtreeVery elderly
dc.subject.meshAdult
dc.subject.meshAged
dc.subject.meshAged, 80 and over
dc.subject.meshAnti-bacterial agents
dc.subject.meshBacteremia
dc.subject.meshCarbapenems
dc.subject.meshColistin
dc.subject.meshCross infection
dc.subject.meshFemale
dc.subject.meshGram-negative bacteria
dc.subject.meshGram-negative bacterial infections
dc.subject.meshHumans
dc.subject.meshMale
dc.subject.meshMicrobial sensitivity tests
dc.subject.meshMiddle aged
dc.subject.meshRetrospective studies
dc.subject.scopusColistin; Escherichia Coli; Resistance Genes
dc.subject.wosPublic, environmental & occupational health
dc.subject.wosInfectious diseases
dc.titleRapid emergence of colistin resistance and its impact on fatality among healthcare-associated infections
dc.typeArticle
dc.wos.quartileN/A
dspace.entity.typePublication
local.contributor.departmentTıp Fakültesi/Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Ana Bilim Dalı
local.indexed.atPubMed
local.indexed.atWOS
local.indexed.atScopus

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