Publication:
Inflammation and oxidative stress markers and their relationship in kidney transplant recipients

dc.contributor.authorDirican, Melahat
dc.contributor.authorKırhan, Emine
dc.contributor.authorKoca, Nizameddin
dc.contributor.authorKacan, Selen Baloğlu
dc.contributor.authorErsoy, Alparslan
dc.contributor.authorSarandöl, Emre
dc.contributor.buuauthorDirican, Melahat
dc.contributor.buuauthorERSOY, ALPARSLAN
dc.contributor.buuauthorSARANDÖL, EMRE
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentBiyokimya Ana Bilim Dalı
dc.contributor.researcheridESK-6562-2022
dc.contributor.researcheridCPX-5894-2022
dc.contributor.researcheridDXM-3644-2022
dc.date.accessioned2024-11-18T09:28:54Z
dc.date.available2024-11-18T09:28:54Z
dc.date.issued2022-07-01
dc.description.abstractObjective: Inflammation and oxidative stress are the 2 well-known physiopathological processes involved in the onset and progression of atherosclerosis and can play role in the poor prognosis of kidney transplantation. However, there is no satisfactory evidence for their markers to be used for the diagnosis and/or follow-up of cardiovascular disease in daily practice. We aimed to investigate inflammation and oxidative stress markers in kidney transplant recipients long after transplantation.Methods: This study was carried out with 62 kidney transplant recipients (34 females and 28 males) who had received a successful transplant at least before 6 months. A group of 50 healthy individuals (28 females and 22 males) were selected as controls.Results: Homocysteine, advanced glycation end products, high sensitivity C-reactive protein, insulin-like growth factor-1, protein S-100B, and vitamin A levels were higher; vitamin E levels and paraoxonase and arylesterase activities were significantly lower in kidney transplant recipients.Conclusion: Kidney transplant recipients are exposed to inflammation and oxidative stress a long time after kidney transplantation. These processes initiated by the body in order to defend itself may damage the tissues after a certain stage, so further studies investigating treatment strategies for reducing inflammation and oxidative stress load and their effects on the prognosis of kidney transplant recipients are needed.
dc.identifier.doi10.5152/turkjnephrol.2022.21075
dc.identifier.endpage256
dc.identifier.issue3
dc.identifier.startpage250
dc.identifier.urihttps://doi.org/10.5152/turkjnephrol.2022.21075
dc.identifier.urihttps://turkjnephrol.org/en/inflammation-and-oxidative-stress-markers-and-their-relationship-in-kidney-transplant-recipients-137076
dc.identifier.urihttps://hdl.handle.net/11452/47997
dc.identifier.volume31
dc.identifier.wos000838716100010
dc.indexed.wosWOS.ESCI
dc.language.isoen
dc.publisherAves
dc.relation.journalTurkish Journal of Nephrology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectGlycation end-products
dc.subjectGrowth-factor-i
dc.subjectIgf-binding protein-3
dc.subjectBody-mass index
dc.subjectSerum paraoxonase
dc.subjectHormones
dc.subjectDisease
dc.subjectKidney transplantation
dc.subjectOxidative stress
dc.subjectInflammation
dc.subjectUrology & nephrology
dc.titleInflammation and oxidative stress markers and their relationship in kidney transplant recipients
dc.typeArticle
dspace.entity.typePublication
local.contributor.departmentTıp Fakültesi/Biyokimya Ana Bilim Dalı
local.contributor.departmentTıp Fakültesi/Nefroloji ve Transplantasyon Ana Bilim Dalı
relation.isAuthorOfPublication3b0ea0d7-f953-4c53-9e92-e260b04f90b4
relation.isAuthorOfPublication9529fb52-20cd-4fb3-9767-19121683aa62
relation.isAuthorOfPublication.latestForDiscovery3b0ea0d7-f953-4c53-9e92-e260b04f90b4

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