Publication: Comparison of esmolol to nitroglycerine in controlling hypotension during nasal surgery
dc.contributor.author | Güney, Ayla | |
dc.contributor.author | Kaya, Fatma Nur | |
dc.contributor.author | Yavaşcaoğlu, Belgin | |
dc.contributor.author | Gurbet, Alp | |
dc.contributor.author | Selmi, Nazan Has | |
dc.contributor.author | Kaya, Şener | |
dc.contributor.author | Kutlay, Oya | |
dc.contributor.buuauthor | Güney, Ayla | |
dc.contributor.buuauthor | KAYA, FATMA NUR | |
dc.contributor.buuauthor | GURBET, ALP | |
dc.contributor.buuauthor | YAVAŞCAOĞLU, BELGİN | |
dc.contributor.buuauthor | Selmi, Nazan Has | |
dc.contributor.buuauthor | Kaya, Şener | |
dc.contributor.buuauthor | Kutlay, Oya | |
dc.contributor.department | Uludağ Üniversitesi/Tıp Fakültesi/Anesteziyoloji ve Reanimasyon Anabilim Dalı. | |
dc.contributor.orcid | 0000-0003-4820-2288 | |
dc.contributor.orcid | 0000-0002-6503-8232 | |
dc.contributor.researcherid | EXO-4828-2022 | |
dc.contributor.researcherid | HPG-2667-2023 | |
dc.contributor.researcherid | AAG-9356-2021 | |
dc.contributor.researcherid | A-7994-2018 | |
dc.contributor.researcherid | FVA-4074-2022 | |
dc.contributor.researcherid | CYU-8986-2022 | |
dc.contributor.researcherid | FFP-7118-2022 | |
dc.date.accessioned | 2024-10-01T13:17:33Z | |
dc.date.available | 2024-10-01T13:17:33Z | |
dc.date.issued | 2012-08-01 | |
dc.description.abstract | Objective: The aim of this study was to compare esmolol to nitroglycerine in terms of effectiveness in controlling hypotension during nasal surgery.Materials and Methods: After approval by our institutional Ethics Committee, 40 patients were recruited and randomized into two drug groups: esmolol (Group E) and nitroglycerine (Group N). In group E, a bolus dose of 500 mu g/kg esmolol was administered over 30 sec followed by continuous administration at a dose of 25-300 mu g/kg/min to maintain systolic arterial pressure at 80 mmHg. In group N, nitroglycerine was administered at a dose of 0.5-2 mu g/kg/min.Results: During the hypotensive period, systolic arterial pressure, diastolic arterial pressure, mean arterial pressure, and heart rate were decreased 24%, 33%, 27% and 35%, respectively, in group E (p<0.001, p<0.001, p<0.001, p<0.001) and were decreased 30%, 33%, 34% and 23%, respectively, in group N (p<0.001, p<0.001, p<0.001, p<0.001). The decrease in heart rate was higher in group E during the hypotensive period (p=0.048). During the recovery period, diastolic arterial pressure and heart rate were decreased 9% and 18%, respectively, in group E (p=0.044, p<0.001). Systolic arterial pressure, diastolic arterial pressure, and mean arterial pressure were decreased 7%, 3% and 7%, respectively, in group N (p=0.049, p=0.451, p=0.045).Conclusion: Esmolol provides hemodynamic stability and good surgical field visibility and should be considered as an alternative to nitroglycerine. | |
dc.identifier.doi | 10.5152/eajm.2012.23 | |
dc.identifier.endpage | 105 | |
dc.identifier.issn | 1308-8734 | |
dc.identifier.issue | 2 | |
dc.identifier.startpage | 99 | |
dc.identifier.uri | https://doi.org/10.5152/eajm.2012.23 | |
dc.identifier.uri | https://www.eajm.org//en/comparison-of-esmolol-to-nitroglycerine-in-controlling-hypotension-during-nasal-surgery-132588 | |
dc.identifier.uri | https://hdl.handle.net/11452/45606 | |
dc.identifier.volume | 44 | |
dc.identifier.wos | 000420428900008 | |
dc.indexed.wos | WOS.ESCI | |
dc.language.iso | en | |
dc.publisher | Aves | |
dc.relation.journal | Eurasian Journal of Medicine | |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi | |
dc.rights | info:eu-repo/semantics/openAccess | |
dc.subject | Anesthesia | |
dc.subject | Controlled hypotension | |
dc.subject | Esmolol hydrochloride | |
dc.subject | Nitroglycerin | |
dc.subject | General & internal medicine | |
dc.title | Comparison of esmolol to nitroglycerine in controlling hypotension during nasal surgery | |
dc.type | Article | |
dspace.entity.type | Publication | |
relation.isAuthorOfPublication | 9e72832d-356c-409c-a2b1-16a2bfe825c3 | |
relation.isAuthorOfPublication | 22870513-5f1d-4e85-9a57-284c8900e112 | |
relation.isAuthorOfPublication | fc04310c-770b-4b0f-89a3-3ed0ffafbc66 | |
relation.isAuthorOfPublication.latestForDiscovery | 9e72832d-356c-409c-a2b1-16a2bfe825c3 |
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