Publication:
Is there a change in the treatment of T1 glottic cancer after CO₂ laser? A comparative study with cold steel

dc.contributor.authorDemir, Uygar Levent
dc.contributor.authorÇevik, Turgut
dc.contributor.authorKasapoğlu, Fikret
dc.contributor.buuauthorDEMİR, UYGAR LEVENT
dc.contributor.buuauthorÇEVİK, TURGUT
dc.contributor.buuauthorKASAPOĞLU, FİKRET
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Kulak Burun Boğaz Anabilim Dalı.
dc.contributor.researcheridAAI-3877-2021
dc.contributor.researcheridCNQ-7672-2022
dc.contributor.researcheridERB-8467-2022
dc.date.accessioned2024-10-07T08:03:04Z
dc.date.available2024-10-07T08:03:04Z
dc.date.issued2018-06-01
dc.description.abstractObjective: Carbon dioxide (CO2) laser provides high local control and disease-specific survival rates with minor morbidity and good quality of life in transoral cordectomy. We aimed to compare the oncological outcome and survival between cold steel and CO2 laser in the treatment of early glottic cancer.Methods: In this retrospective study, the participants were divided into two groups. The first group comprised patients who were operated upon between 2001 and 2007 using cold steel (group 1, n=38), and the second group comprised patients who were operated upon between 2008 and 2016 using CO2 laser (group 2, n=88). Both groups were compared regarding age, gender, pathological grade, T stage, type of cordectomy, margin status, anterior commissure involvement, follow-up, locoregional recurrence, and disease- free survival (DFS).Results: The overall survival rate and DFS were similar between the two groups (94.7% vs. 98.9% and 100% vs. 98.9%, respectively), and no association was found between surgical margin positivity and local recurrence. However, a significant association between the presence of anterior commissure involvement and recurrence was found in all 126 patients (p=0.016). Local recurrence was significantly higher in the group 2 (p=0.024), but it did not affect overall survival and DFS in these patients (100% vs. 94.1%).Conclusion: Although CO2 laser excision is considered to be superior to cold steel regarding surgical time and bleeding control, the local recurrence rates were found to be higher with the laser than the cold steel. Thus, we argue that cases should be selected more carefully concerning the anterior commissure, depth of tumor invasion lateral to vocal muscle, difficulty at endoscopic exposure for lesions with anterior commissure involvement, and reliability of surgical margins at frozen sections.
dc.identifier.doi10.5152/tao.2018.3053
dc.identifier.endpage69
dc.identifier.issn2667-7466
dc.identifier.issue2
dc.identifier.startpage64
dc.identifier.urihttps://doi.org/10.5152/tao.2018.3053
dc.identifier.urihttps://turkarchotolaryngol.net/articles/doi/tao.2018.3053
dc.identifier.urihttps://hdl.handle.net/11452/45946
dc.identifier.volume56
dc.identifier.wos000443089700002
dc.indexed.wosWOS.ESCI
dc.language.isoen
dc.publisherGalenos Yayıncılık
dc.relation.journalTurkish Archives of Otorhinolaryngology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAnterior commissure
dc.subjectLaser-surgery
dc.subjectMargin-status
dc.subjectCordectomy
dc.subjectRecurrence
dc.subjectCarcinoma
dc.subjectScalpel
dc.subjectElectrocautery
dc.subjectInvolvement
dc.subjectResection
dc.subjectGlottic cancer
dc.subjectCo2 laser
dc.subjectCold steel
dc.subjectSurvival
dc.subjectOncological results
dc.subjectOtorhinolaryngology
dc.titleIs there a change in the treatment of T1 glottic cancer after CO₂ laser? A comparative study with cold steel
dc.typeArticle
dspace.entity.typePublication
relation.isAuthorOfPublicationa6f4de0e-11ee-445b-93cd-4e9efb21b490
relation.isAuthorOfPublication42165666-3068-46db-be77-29e26dfc103f
relation.isAuthorOfPublicationcfa6b56d-ac29-4916-8f7c-c5e51b793f11
relation.isAuthorOfPublication.latestForDiscoverya6f4de0e-11ee-445b-93cd-4e9efb21b490

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