Publication:
Omental micrometastasis in endometrial cancer

dc.contributor.authorBayrak, Mehmet
dc.contributor.authorYılmaz, Alpay
dc.contributor.authorYılmaz, Fatih
dc.contributor.authorİlhan, Olcay
dc.contributor.authorAtalay, Fatma Öz
dc.contributor.authorOzan, Hakan
dc.contributor.buuauthorBayrak, Mehmet
dc.contributor.buuauthorYılmaz, Fatih
dc.contributor.buuauthorİlhan, Olcay
dc.contributor.buuauthorÖZ ATALAY, FATMA
dc.contributor.buuauthorOZAN, HAKAN
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentCerrahi Patoloji Kliniği
dc.contributor.orcid0000-0002-9910-8032
dc.contributor.orcid0000-0002-5820-3754
dc.contributor.researcheridDUU-5336-2022
dc.contributor.researcheridC-5252-2015
dc.contributor.researcheridCXA-2700-2022
dc.contributor.researcheridJHC-4482-2023
dc.contributor.researcheridDKZ-4159-2022
dc.date.accessioned2024-07-22T05:19:09Z
dc.date.available2024-07-22T05:19:09Z
dc.date.issued2019-01-01
dc.description.abstractIntroduction: Although there are several reports on omentum metastasis, limited studies have evaluated omental micrometastases, particularly isolated microscopic metastases in endometrial cancer (EC). We performed this study to assess the frequency of omental micrometastasis in EC, especially when the omentum is the only site of extrauterine spread. Methods: A retrospective study was conducted to assess cases of EC with an omental sample during primary surgical treatment for EC at the Gynecological Oncology Unit, Uludag University Hospital, Bursa, Turkey, between January 2005 and May 2018. Results: In total, 435 patients fulfilled the inclusion criteria, which comprised a complete surgical staging. The prevalence of omental metastases was 5.3% (n = 23), regardless of the subtype or clinical stage. Omental micrometastasis was detected in four cases (17.4%). In half of these patients, the omentum was the only site of disease outside the uterus, with an estimated 0.46% of isolated omental involvement. The grade of the endometrioid tumor was found to be statistically correlated with omental metastases (p = 0.01). There was a significant correlation between omental metastasis and positive peritoneal cytology, as well as adnexal involvement (p = 0.001 and p = 0.03, respectively). Conclusion: We recommend omentectomy routinely in serous EC. In addition, we suggest selective omentectomy in patients with EC who have concomitant adnexal involvement or grade 3 tumors.
dc.identifier.doi10.1159/000501727
dc.identifier.eissn2296-5262
dc.identifier.endpage469
dc.identifier.issn2296-5270
dc.identifier.issue9
dc.identifier.startpage466
dc.identifier.urihttps://doi.org/10.1159/000501727
dc.identifier.urihttps://karger.com/ort/article/42/9/466/263579/Omental-Micrometastasis-in-Endometrial-Cancer
dc.identifier.urihttps://hdl.handle.net/11452/43350
dc.identifier.volume42
dc.identifier.wos000484667500005
dc.indexed.wosWOS.SCI
dc.language.isoen
dc.publisherKarger
dc.relation.journalOncology Research and Treatment
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectOmentectomy
dc.subjectBiopsy
dc.subjectAppendectomy
dc.subjectMetastasis
dc.subjectEndometrial cancer
dc.subjectMicrometastases
dc.subjectOmentectomy
dc.subjectScience & technology
dc.subjectLife sciences & biomedicine
dc.subjectOncology
dc.titleOmental micrometastasis in endometrial cancer
dc.typeArticle
dspace.entity.typePublication
local.contributor.departmentTıp Fakültesi/Jinekolojik Onkoloji Kliniği
local.contributor.departmentTıp Fakültesi/Cerrahi Patoloji Kliniği
relation.isAuthorOfPublication1ce7be89-9690-438f-b756-18b50aad8607
relation.isAuthorOfPublication9dfbd47f-e25c-496c-ad06-d28af10bd48c
relation.isAuthorOfPublication.latestForDiscovery1ce7be89-9690-438f-b756-18b50aad8607

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