Publication: Sd-oct assessment of macular and optic nerve alterations in patients recovered from covid-19
dc.contributor.author | Yıldız, Ayşegül Mavi | |
dc.contributor.author | Gündüz, Gamze Ucan | |
dc.contributor.author | Yalçınbayır, Özgür | |
dc.contributor.author | Öztürk, Nilüfer Aylin Acet | |
dc.contributor.author | Avcı, Remzi | |
dc.contributor.author | Coşkun, Funda | |
dc.contributor.buuauthor | UÇAN GÜNDÜZ, GAMZE | |
dc.contributor.buuauthor | YALÇINBAYIR, ÖZGÜR | |
dc.contributor.buuauthor | ACET ÖZTÜRK, NİLÜFER AYLİN | |
dc.contributor.buuauthor | COŞKUN, NECMİYE FUNDA | |
dc.contributor.department | Tıp Fakültesi | |
dc.contributor.department | Göğüs Hastalıkları Ana Bilim Dalı | |
dc.contributor.orcid | 0000-0003-3604-8826 | |
dc.contributor.orcid | 0000-0002-6375-1472 | |
dc.contributor.orcid | 0000-0002-7311-5277 | |
dc.contributor.researcherid | AAH-6661-2021 | |
dc.contributor.researcherid | IYJ-9408-2023 | |
dc.contributor.researcherid | Z-1424-2019 | |
dc.contributor.researcherid | AAD-1271-2019 | |
dc.date.accessioned | 2024-11-21T10:03:12Z | |
dc.date.available | 2024-11-21T10:03:12Z | |
dc.date.issued | 2022-03-28 | |
dc.description.abstract | Objective: To quantify microstructutal alterations in the macula and peripapillary retinal nerve fibre layer (RNFL) in patients recovered from coronavirus disease 2019 (COVID-19) using spectral domain optic coherence tomography (SD-OCT).Design: Retrospective, observational.Participants: This comparative, cross-sectional study included patients who recovered from COVID-19 (Group 1) and age- and sex-matched normal controls (Group 2).Methods: A comprehensive ophthalmic examination, including best-corrected visual acuity and biomicroscopic anterior and posterior segment examination was performed. SD-OCT analysis of the macula and peripapillary RNFL was obtained for each participant. In addition, patient demographics and comorbidities were recorded.Results: 238 eyes of 122 subjects (Group 1: n = 63; Group 2: n = 59) were included. The incidence of coexisting comorbidity was higher in Group 1 (n = 26/63, 41.3%) compared with Group 2 (n = 12/59, 20.3%) (p = 0.013). The central foveal thickness (CFT) was significantly higher in Group 1 (271.0 +/- 26.8 mu m) than Group 2 (263.2 +/- 22.0 mu m) (p = 0.015). The average outer nuclear layer (ONL) thickness at central fovea in Group 1 (85.4 +/- 13.3 mm) was significantly thicker than that in Group 2 (81.4 +/- 15.2 mu m) (p = 0.035). The mean peripapillary RNFL thickness of Group 1 (102.6 +/- 8.8 mu m) and Group 2 (100.9 +/- 8.3 mu m) were similar (p = 0.145). The mean choroidal thickness of groups at the fovea and at 1500 mu m nasal and temporal to the fovea were not significantly different (p> 0.05 for all).Conclusion: Significant thickness alterations in individual retinal layers and CFT was detected in post-COVID-19 patients. The increase in CFT and ONL thickness might be attributed to direct infection or viral-induced inflammatory response of retina. | |
dc.identifier.doi | 10.1016/j.jcjo.2021.06.019 | |
dc.identifier.endpage | 81 | |
dc.identifier.issn | 0008-4182 | |
dc.identifier.issue | 2 | |
dc.identifier.startpage | 75 | |
dc.identifier.uri | https://doi.org/10.1016/j.jcjo.2021.06.019 | |
dc.identifier.uri | https://www.sciencedirect.com/science/article/pii/S0008418221002453?via%3Dihub | |
dc.identifier.uri | https://hdl.handle.net/11452/48281 | |
dc.identifier.volume | 57 | |
dc.identifier.wos | 000775968000022 | |
dc.indexed.wos | WOS.SCI | |
dc.language.iso | en | |
dc.publisher | Canadian Ophthal Soc | |
dc.relation.journal | Canadian Journal of Ophthalmology-Journal Canadien D Ophtalmologie | |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi | |
dc.rights | info:eu-repo/semantics/openAccess | |
dc.subject | Microglia | |
dc.subject | Ophthalmology | |
dc.title | Sd-oct assessment of macular and optic nerve alterations in patients recovered from covid-19 | |
dc.type | Article | |
dspace.entity.type | Publication | |
local.contributor.department | Tıp Fakültesi/Göz Hastalıkları Ana Bilim Dalı | |
local.contributor.department | Tıp Fakültesi/Göğüs Hastalıkları Ana Bilim Dalı | |
relation.isAuthorOfPublication | fcd16549-6bb4-4c75-9919-689a032002f2 | |
relation.isAuthorOfPublication | e21cc14e-0a29-42c8-a7a0-93bd3c780b36 | |
relation.isAuthorOfPublication | 1fbb03ab-16d7-4784-86fd-239b055bc24f | |
relation.isAuthorOfPublication | 061153e8-bbd9-4c2a-97f6-dc51171a1143 | |
relation.isAuthorOfPublication.latestForDiscovery | fcd16549-6bb4-4c75-9919-689a032002f2 |
Files
Original bundle
1 - 1 of 1