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Solid pseudopapillary neoplasms of the pancreas: Is there a factor determining the prognosis? Experience of a single institution

dc.contributor.buuauthorKILIÇTURGAY, SADIK AYHAN
dc.contributor.buuauthorKılıçturgay, Sadık Ayhan
dc.contributor.buuauthorTaşar, Pınar
dc.contributor.buuauthorTAŞAR, PINAR
dc.contributor.departmentBursa Uludağ Üniversitesi/Tıp Fakültesi/Genel Cerrahi Anabilim Dalı.
dc.date.accessioned2024-10-04T13:12:47Z
dc.date.available2024-10-04T13:12:47Z
dc.date.issued2022-08-26
dc.description.abstractSolid pseudopapillary neoplasms (SPNs) are frequently seen in young women. Although the behavior pattern varies, these rare lesions generally have a low malignant potential. In this study, the aim was to investigate the effect of clinicopathological features of lesions on the recurrence in and survival of patients. In this study, patients of our clinic who were pathologically diagnosed with SPN after pancreatic surgery between July 2008 and December 2020 were evaluated retrospectively. Patients' age, gender, comorbidities, symptoms at the time of application, preoperative CA 19-9, CEA value, preoperative cross-sectional diagnostic imaging method and lesion characteristics, surgery, postoperative complications, length of hospital stay, and histopathological features were evaluated. Early and late mortality, overall survival, disease-free survival, and recurrence rate were determined. Four of the 23 patients diagnosed with SPN were male and the median age was 29 (23-47) years. Of the study patients, 69.56% experienced pain symptoms and 30.43% were asymptomatic. The median tumor size was 4 cm (1.5-15). The most common surgical procedure was distal pancreatectomy (56.5%). The median length of hospital stays was 5 (3-120) days and morbidity was observed in 9 cases (39.13%). The mortality rate was 4.35%. The mean follow-up period in the series was 53 (8-132) months and none of the patients developed recurrence. In this study, no significant difference was found regarding recurrence in patients with SPN with histopathologically aggressive biological behavior. The overall survival rate was 95.7%. SPNs are rare lesions with low malignant potential. SPNs are associated with longer-term survival after surgical resection.
dc.identifier.doi10.1097/MD.0000000000030101
dc.identifier.issn0025-7974
dc.identifier.issue34
dc.identifier.urihttps://doi.org/10.1097/MD.0000000000030101
dc.identifier.urihttps://hdl.handle.net/11452/45905
dc.identifier.volume101
dc.identifier.wos000847532100055
dc.indexed.wosWOS.SCI
dc.language.isoen
dc.publisherLippincott Williams & Wilkins
dc.relation.journalMedicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectSurgical outcomes
dc.subjectFeatures
dc.subjectTumors
dc.subjectMortality
dc.subjectPrognosis
dc.subjectRecurrence
dc.subjectSolid pseudopapillary neoplasia
dc.subjectSurgery
dc.subjectScience & technology
dc.subjectLife sciences & biomedicine
dc.subjectMedicine, general & internal
dc.subjectGeneral & internal medicine
dc.titleSolid pseudopapillary neoplasms of the pancreas: Is there a factor determining the prognosis? Experience of a single institution
dc.typeArticle
dspace.entity.typePublication
relation.isAuthorOfPublicationc44cb84a-5b92-4f00-b59f-f1b243f1171c
relation.isAuthorOfPublicationa197cfe6-cc32-482e-b3af-f80d106d2f1f
relation.isAuthorOfPublication.latestForDiscoverya197cfe6-cc32-482e-b3af-f80d106d2f1f

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