Publication: Preemptive analgesic effects of intravenous paracetamol in total abdominal hysterectomy
dc.contributor.author | Arıcı, Semih | |
dc.contributor.author | Gurbet, Alp | |
dc.contributor.author | Türker, Gürkan | |
dc.contributor.author | Yavaşcaoğlu, Belgin | |
dc.contributor.author | Şahin, Şükran | |
dc.contributor.buuauthor | Arıcı, Semih | |
dc.contributor.buuauthor | GURBET, ALP | |
dc.contributor.buuauthor | TÜRKER, YUNUS GÜRKAN | |
dc.contributor.buuauthor | YAVAŞCAOĞLU, BELGİN | |
dc.contributor.buuauthor | Şahin, Şükran | |
dc.contributor.department | Uludağ Üniversitesi/Tıp Fakültesi/Anestezi ve Reanimasyon Anabilim Dalı. | |
dc.contributor.orcid | 0000-0002-6503-8232 | |
dc.contributor.orcid | 0000-0002-3019-581X | |
dc.contributor.orcid | 0000-0003-4820-2288 | |
dc.contributor.researcherid | A-7994-2018 | |
dc.contributor.researcherid | AAI-7914-2021 | |
dc.contributor.researcherid | JZE-5924-2024 | |
dc.contributor.researcherid | AAI-6642-2021 | |
dc.contributor.researcherid | AAG-9356-2021 | |
dc.date.accessioned | 2024-09-18T08:10:27Z | |
dc.date.available | 2024-09-18T08:10:27Z | |
dc.date.issued | 2009-04-01 | |
dc.description.abstract | Objectives: Paracetamol is primarily thought to be a cyclooxygenase inhibitor acting through the central nervous system. Indirect effects of paracetamol are through the serotoninergic system as a non-opioid analgesic. In this study, total abdominal hysterectomy patients were given intravenous (iv) paracetamol 1 g preoperatively or intraoperatively to assess its postoperative analgesic effects.Methods: 90 patients undergoing total abdominal hysterectomy were enrolled into the study. Patients were randomized into three groups: in Group I, iv paracetamol 1 g was given 30 minutes prior to induction. In Group II, iv paracetamol 1 g was given prior to skin closure. Group III served as the control group and received saline as placebo. Postoperatively, all patients received morphine via patient-controlled analgesia pump. Postoperatively, rest and activity pain scores, sedation scores, hemodynamic parameters, postoperative morphine consumption, side effects, patient satisfaction, and total hospital stay were recorded.Results: In the control group, at rest and movement pain scores and total morphine consumption via patient-controlled analgesia were higher than in Groups I and II. When Groups I and II were compared, total morphine consumption was much greater in Group II. Intravenous paracetamol intraoperatively and postoperatively did not result in any hemodynamic effects.Conclusion: In total abdominal hysterectomy, preemptive iv paracetamol 1 g provided good quality postoperative analgesia, with decreased consumption of morphine and minimal side effects. | |
dc.identifier.endpage | 61 | |
dc.identifier.issn | 1300-0012 | |
dc.identifier.issue | 2 | |
dc.identifier.startpage | 54 | |
dc.identifier.uri | https://hdl.handle.net/11452/44875 | |
dc.identifier.volume | 21 | |
dc.identifier.wos | 000421060300002 | |
dc.indexed.wos | WOS.ESCI | |
dc.language.iso | en | |
dc.publisher | Kare Publ | |
dc.relation.journal | Agri-The Journal of The Turkish Society of Algology | |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi | |
dc.rights | info:eu-repo/semantics/closedAccess | |
dc.subject | Laparotomy | |
dc.subject | Morphine | |
dc.subject | Paracetamol | |
dc.subject | Postoperative analgesia | |
dc.subject | General & internal medicine | |
dc.title | Preemptive analgesic effects of intravenous paracetamol in total abdominal hysterectomy | |
dc.type | Article | |
dspace.entity.type | Publication | |
relation.isAuthorOfPublication | fc04310c-770b-4b0f-89a3-3ed0ffafbc66 | |
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relation.isAuthorOfPublication | 22870513-5f1d-4e85-9a57-284c8900e112 | |
relation.isAuthorOfPublication.latestForDiscovery | fc04310c-770b-4b0f-89a3-3ed0ffafbc66 |