Publication:
Perforation of the small intestine caused by enteropathy-associated t cell lymphoma

dc.contributor.buuauthorKabul, Selva
dc.contributor.buuauthorKABUL, SELVA
dc.contributor.buuauthorUğras, Nesrin
dc.contributor.buuauthorUĞRAŞ, NESRİN
dc.contributor.buuauthorYerci, Ömer
dc.contributor.buuauthorYERCİ, ÖMER
dc.contributor.buuauthorÖztürk, Ersin
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentPatoloji Ana Bilim Dalı
dc.contributor.researcheridAAH-2716-2021
dc.contributor.researcheridCAF-3650-2022
dc.date.accessioned2024-09-25T05:57:20Z
dc.date.available2024-09-25T05:57:20Z
dc.date.issued2018-09-01
dc.description.abstractEnteropathy-associated T cell lymphoma is a rare lymphoma specific to the gastrointestinal system, arising from intraepithelial T lymphocytes, that is often associated with celiac disease. We report a 53-year-old female patient with no previous disease who presented with severe abdominal pain. Physical examination revealed diffuse abdominal tenderness and abdominal guarding and the patient underwent emergency surgery with a diagnosis of acute abdomen. During the operation, a 20-cm mass was found located on Treitz ligament, invading the duodenum and pancreatic head and perforating the jejunum. Histologically, medium-sized monomorphic atypical lymphocyte infiltration with dark nucleus and narrow cytoplasm was seen in the layers of mucosa, submucosa, muscular wall, and serosa of the duodenum. The final pathological diagnosis was "enteropathy-associated T cell lymphoma type 2" based on immunohistochemical and serological findings. Based on the World Health Organization 2008 criteria, enteropathy-associated T cell lymphoma has two subtypes. Type 1 enteropathy-associated T cell lymphoma is associated with celiac disease and has HLA DQ2 and HLA DQ8 genotype. Enteropathy-associated T cell lymphoma 2 enteropathy-associated T cell lymphoma seldom occurs and is not associated with celiac disease.
dc.identifier.doi10.5152/turkjsurg.2017.3278
dc.identifier.endpage255
dc.identifier.issn2564-6850
dc.identifier.issue3
dc.identifier.startpage253
dc.identifier.urihttps://doi.org/10.5152/turkjsurg.2017.3278
dc.identifier.urihttps://hdl.handle.net/11452/45178
dc.identifier.volume34
dc.identifier.wos000446227800021
dc.indexed.wosWOS.ESCI
dc.language.isoen
dc.publisherAves
dc.relation.journalTurkish Journal Of Surgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.subjectLymphoma
dc.subjectEnteropathy
dc.subjectSmall intestine
dc.subjectScience & technology
dc.subjectLife sciences & biomedicine
dc.subjectSurgery
dc.titlePerforation of the small intestine caused by enteropathy-associated t cell lymphoma
dc.typeArticle
dspace.entity.typePublication
local.contributor.departmentTıp Fakültesi/Patoloji Ana Bilim Dalı
local.contributor.departmentTıp Fakültesi/Genel Cerrahi Ana Bilim Dalı
relation.isAuthorOfPublication76775155-c27b-4421-bb7b-b154db42aac3
relation.isAuthorOfPublicationdd613ef2-8621-4e20-8c27-0393f7c8e632
relation.isAuthorOfPublication559e3ec8-742a-46d4-bf58-8bb138ca553d
relation.isAuthorOfPublication.latestForDiscovery76775155-c27b-4421-bb7b-b154db42aac3

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