Publication:
Oxidative stress and antioxidants-a critical review on in vitro antioxidant assays

dc.contributor.authorKotha, Raghavendhar R. R.
dc.contributor.authorTareq, Fakir Shahidullah
dc.contributor.authorLuthria, Devanand L. L.
dc.contributor.buuauthorYıldız, Elif
dc.contributor.buuauthorYILDIZ, ELİF
dc.contributor.departmentBursa Uludağ Üniversitesi/Keleş Meslek Yüksek Okulu.
dc.contributor.orcid0000-0003-1356-9012
dc.contributor.researcheridAAG-6424-2021
dc.date.accessioned2024-09-23T05:22:17Z
dc.date.available2024-09-23T05:22:17Z
dc.date.issued2022-12-01
dc.description.abstractAntioxidants have been widely studied in the fields of biology, medicine, food, and nutrition sciences. There has been extensive work on developing assays for foods and biological systems. The scientific communities have well-accepted the effectiveness of endogenous antioxidants generated in the body. However, the health efficacy and the possible action of exogenous dietary antioxidants are still questionable. This may be attributed to several factors, including a lack of basic understanding of the interaction of exogenous antioxidants in the body, the lack of agreement of the different antioxidant assays, and the lack of specificity of the assays, which leads to an inability to relate specific dietary antioxidants to health outcomes. Hence, there is significant doubt regarding the relationship between dietary antioxidants to human health. In this review, we documented the variations in the current methodologies, their mechanisms, and the highly varying values for six common food substrates (fruits, vegetables, processed foods, grains, legumes, milk, and dairy-related products). Finally, we discuss the strengths and weaknesses of the antioxidant assays and examine the challenges in correlating the antioxidant activity of foods to human health.
dc.identifier.doi10.3390/antiox11122388
dc.identifier.issue12
dc.identifier.urihttps://doi.org/10.3390/antiox11122388
dc.identifier.urihttps://hdl.handle.net/11452/45001
dc.identifier.volume11
dc.identifier.wos000900321800001
dc.indexed.wosWOS.SCI
dc.language.isoen
dc.publisherMdpi
dc.relation.journalAntioxidants
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectRadical scavenging activity
dc.subjectPhenolic-compounds
dc.subjectSuperoxide-dismutase
dc.subjectLipid-peroxidation
dc.subjectSpectrophotometric assay
dc.subjectCardiovascular health
dc.subjectBioactive compounds
dc.subjectReactive oxygen
dc.subjectCapacity assays
dc.subjectNitric-oxide
dc.subjectOxidative stress
dc.subjectAntioxidants
dc.subjectFoods
dc.subjectAntioxidant assays limitations
dc.subjectChallenges in correlating with health benefits
dc.subjectScience & technology
dc.subjectLife sciences & biomedicine
dc.subjectBiochemistry & molecular biology
dc.subjectChemistry, medicinal
dc.subjectFood science & technology
dc.subjectBiochemistry & molecular biology
dc.subjectPharmacology & pharmacy
dc.subjectFood science & technology
dc.titleOxidative stress and antioxidants-a critical review on in vitro antioxidant assays
dc.typeReview
dspace.entity.typePublication
relation.isAuthorOfPublication8d3e9e4f-0858-4a7a-9b20-6a16e47ea408
relation.isAuthorOfPublication.latestForDiscovery8d3e9e4f-0858-4a7a-9b20-6a16e47ea408

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