Publication:
Guillain-barre syndrome and human immunodeficiency virus

dc.contributor.authorGirgin, Nermin Kelebek
dc.contributor.authorİsçimen, Remzi
dc.contributor.authorYılmaz, Emel
dc.contributor.authorKahveci, S. Ferda
dc.contributor.authorKutlay, Oya
dc.contributor.buuauthorKELEBEK GİRGİN, NERMİN
dc.contributor.buuauthorİŞÇİMEN, REMZİ
dc.contributor.buuauthorYILMAZ, EMEL
dc.contributor.buuauthorKAHVECİ, FERDA ŞÖHRET
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Anesteziyoloji ve Reanimasyon Anabilim Dalı/Yoğun Bakım Ünitesi.
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Enfeksiyon Hastalıkları ve Mikrobiyoloji Anabilim Dalı.
dc.contributor.orcid0000-0003-4820-2288
dc.contributor.researcheridAAG-9356-2021
dc.contributor.researcheridAAH-7250-2019
dc.contributor.researcheridHKP-2533-2023
dc.contributor.researcheridAAI-8104-2021
dc.date.accessioned2024-10-01T12:46:04Z
dc.date.available2024-10-01T12:46:04Z
dc.date.issued2014-04-01
dc.description.abstractGuillain-Barre syndrome (GBS) is an acute disease characterised by symmetrical muscle weakness, loss of sensation and reflex. There is usually a viral infection at the beginning of the disease. Here, we report a GBS case which did not respond to any treatment strategy at first and was diagnosed as Human Immunodeficiency Virus positive (HIV+) during the search for the aetiology. A 32-year-old male patient who presented to a medical centre with symptoms of gait disturbance and arm and leg numbness was found to have albuminocytologic dissociation upon cerebrospinal fluid examination. After the diagnosis of GBS, immunoglobulin G (IVIG) therapy (400 mg kg(-1) day-1 5 days) was started as a standard therapy. This therapy was repeated due to a lack of improvement of symptoms. During this therapy, the patient was sent to our clinic with symptoms of respiratory failure and tetraplegia. He was conscious, cooperative, haemodynamically stable and his arterial blood gas analyses were: pH: 7.28, PaO2 : 74.4 mmHg, PCO2 : 63.8 mmHg. He was intubated, mechanically ventilated and underwent plasmapheresis. After the investigation of aetiology, HIV(+), CD4/ CD8: 0.17, absolute CD4: 71 cells mL(-1) were detected and antiretroviral therapy was started. The patient died from multiple organ failure due to sepsis on day 35. In conclusion, HIV infection should be kept in mind in GBS patients, especially those not responding to routine treatment. As a result, not only could the patient receive early and adequate treatment, but also HIV infection transmission would be avoided.
dc.identifier.doi10.5152/TJAR.2013.51
dc.identifier.endpage102
dc.identifier.issn2667-677X
dc.identifier.issue2
dc.identifier.startpage100
dc.identifier.urihttps://doi.org/10.5152/TJAR.2013.51
dc.identifier.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894156/
dc.identifier.urihttps://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC4894156&blobtype=pdf
dc.identifier.urihttps://hdl.handle.net/11452/45605
dc.identifier.volume42
dc.identifier.wos000218632700008
dc.indexed.wosWOS.ESCI
dc.language.isoen
dc.publisherAves
dc.relation.journalTurkish Journal of Anaesthesiology and Reanimation
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectInfection
dc.subjectPhase
dc.subjectGuillain-barre syndrome
dc.subjectHuman immunodeficiency virus
dc.subjectIntensive care
dc.subjectAnesthesiology
dc.titleGuillain-barre syndrome and human immunodeficiency virus
dc.typeArticle
dspace.entity.typePublication
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relation.isAuthorOfPublication.latestForDiscoverya457eb47-d4c0-448f-92d1-9b122c063bb0

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